IRIS
TONETTI, MICHELA
 Distribuzione geografica
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Continente #
EU - Europa 8.357
Totale 8.357
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Nazione #
IT - Italia 8.357
Totale 8.357
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Città #
Genova 6.158
Rapallo 819
Genoa 694
Vado Ligure 675
Bordighera 11
Totale 8.357
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Nome #
A novel dimeric fluoropyrimidine molecule behaves as a remote precursor of 5-Fluoro-2'-deoxyuridine in human erythrocytes. 144
Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses 134
Impairment of the Golgi GDP-L-fucose transport and unresponsiveness to fucose replacement therapy in LAD II patients 131
N-linked Glycans of Chloroviruses Sharing a Core Architecture without Precedent 127
The Autonomous Glycosylation of Large DNA Viruses 127
Fucose supplementation in LAD II 125
Identification of an L-rhamnose synthetic pathway in two nucleocytoplasmic large DNA viruses 125
Enhanced antitumor activity of adriamycin by encapsulation in mouse erythrocytes targeted to liver and lungs. 124
Leukocyte adhesion deficiency (LAD) type II/carbohydrate deficient glycoprotein (CDG)IIc-founder effect and genotype/phenotype correlation 123
Impairment of the Golgi GDP-L-fucose transport and unresponsiveness to fucose replacement therapy in LAD II patients 121
Encapsulation of doxorubicin in liver-targeted erythrocytes increases the therapeutic index of the drug in a murine metastatic model 121
Chloroviruses have a sweet tooth 121
Effects of microRNAs on fucosyltransferase 8 (FUT8) expression in hepatocarcinoma cells 119
Characterization of a UDP-N-acetylglucosamine biosynthetic pathway encoded by the giant DNA virus Mimivirus 117
Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses 116
Synthesis of GDP-L-Fucose by the Human FX protein 115
Multiple small molecular weight guanine nucleotide-binding proteins in human erythrocyte membranes 113
Synergistic Cytotoxicity of Carboplatin and Divicine on Murine Erythroleukemic Cells 112
Use of glutaraldehyde treated autologous human erythrocytes for hepatic targeting of doxorubicin. 112
Giant virus Megavirus chilensis encodes the biosynthetic pathway for uncommon acetamido sugars 112
Structure of N-linked oligosaccharides attached to chlorovirus PBCV-1 major capsid protein reveals unusual class of complex N-glycans 112
Enhanced intracellular activation of carboplatin in hemoglobin-synthesizing versus undifferentiated erythroleukemic cells 111
Giant DNA Virus Mimivirus Encodes Pathway for Biosynthesis of Unusual Sugar 4-Amino-4,6-dideoxy-D-glucose (Viosamine). 110
Core fucosylation of N-linked glycans in leukocytes adhesion deficiency/congenital disorder of glycosylation IIc fibroblasts 109
Enhanced formation of reactive species from cis- diammine (1,1-cyclobutane-dicarboxylato) platinum (II) (Carboplatin) in the presence of oxygen free radicals 109
Paramecium bursaria Chlorella Virus 1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose 109
Leukocyte Adhesion Deficiency 108
The rare sugar N-acetylated viosamine is a major component of Mimivirus fibers 108
Probing the catalytic mechanism of GDP-4-keto-6-deoxy-D-mannose epimerase/reductase by kinetic and crystallographic characterization of site specific mutants 106
Expression, Purification and Characterization of GDP-D-Mannose 4,6-Dehydratase from Escherichia Coli 104
Carbohydrates: Translation from sticky to sweet 103
The N-glycan structures of the antigenic variants of chlorovirus PBCV-1 major capsid protein help to identify the virus-encoded glycosyltransferases 102
Occurence in human cells of a metabolic pathway converting dTDP-D-glucose to 6-deoxyhexoses 100
Biophysical Approaches to Solve the Structures of the Complex Glycan Shield of Chloroviruses 98
Defective intracellular activity of GDP-D-mannose 4,6 dehydratase in leukocytes adhesion deficiency Type II (LAD II) syndrome. 97
Kinetic and Crystallographic Analises Support a Sequential-ordered Bi Bi Catalytic Mechanism for Escherichia Coli Glucose-1-Thymidyltransferase. 95
Quartz dissolution by the sponge Chondrosia reniformis (Porifera, Demospongiae) 95
Human Red Blood Cells (RBC) as Bioreactors for the Production and the Release of Fluoropyrimidine Drugs from Encapsulated Pro-Drugs 94
Encapsulation of Glucose Oxidase in mouse erythrocytes :an experimental model of oxidant-induced cytotoxicity and a means for splenic targeting of carrier erythrocytes. 94
Cloning and expression of two enzymes involved in the de novo synthesis of GDP-L-fucose in PBCV-1 93
Cloning and expression of the human NADP(H)-binding protein FX 92
Engineered erythrocytes as carriers and bioreactors for biomedical research 91
Quaternary assembly and crystal structure of GDP-D-mannose 4,6 dehydratase from Paramencium bursaria Chlorella virus 89
In vitro reconstruction of the complete metabolic pathway that converts GDP-D-mannose to GDP-L-fucose in bacterial cells. 88
Effect of defective import of GDP-fucose into Golgi apparatus on glycoconjugates composition in cells from LAD II patient 87
Defective intracellular activity of GDP-D-mannose 4,6 dehydratase in leukocyte adhesion deficiency type II (LAD II) 85
In vivo liver and lung targeting of adriamycin encapsulated in glutaraldehyde-treated murine erythrocytes. 85
Identification of the molecular basis of leukocytes adhesion deficiency Type II (LAD II) syndrome 85
Characterization of the residual fucose-containing glycoconjugates in LAD II/CDGS IIc cells 84
Tissue Specific Transplantation Antigen P35B (= GDP-4-keto-6-D-Deoxymannose Epimerase-Reductase) (TSTA3) 84
Preliminary structural characterization of recombinant GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from E.coli 83
Core fucosylation of N-linked glycans in Lad II Cdg IIc fibroblasts 82
The glycosyaltion in nucleo-cytoplasmic large DNA viruses (NVLDV) 81
Use of mass spectrometry to characterize the products of two enzymes encoded by Chlorella Virus PBCV-1 80
Time -dependent normalization of defective Slex expression and GDP-mannose 4,6 dehydratase (GMD) activity in long-term culture of lymphocytes from a LAD II patients. 78
Primary structure,cDNA sequence and tissue localization of the human NADP-binding protein FX. 78
Engineered Erythrocytes as Biotechnological Tools for Advanced Therapies 78
Engineered erythrocytes as carriers and bioreactors. 78
Synthesis and characterization of a specific peptide nuclei acid that inhibits expression of inducible NO synthase 77
The Chlorella virus PBCV-1 encodes two enzymes involved in the de novo synthesis of GDP-L-fucose and GDP-D-rhamnose 77
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from E. coli, a key enzyme in the biosynthesis of GDP-L-fucose displays the strucutral characteristics of the RED protein homology superfamily 77
Extracellular ATP Potentiates Nitric Oxide Synthase Expression Induced by Lipopolysaccharide in Raw 264.7 Murine Macrophages 76
Effects of the murine L929 and L1210 cell lines on nitric oxide and TNFalfa production by RAW 264.7 murine macrophages. 74
Structural and enzymatic characterization of human recombinant GDP-D-mannose 4,6 dehydratase 74
The high resolution structure of GDP-4-keto-6-deoxy-D-mannose epimerase/reductase. 72
Differential terminal fucosylation of N-Linked glycans versus protein O-Fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc). 71
The NADP(H)-binding protein FX is an enzyme involved in the synthesis of GDP-L-fucose. 70
Liver targeting of autologous erythrocytes loaded with doxorubicin 70
Differential terminal fucosylation of N-Linked glycans versus protein O-Fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc) 69
Human and Murine Erythrocytes as Bioreactors releasing the antineoplastic drug 5-fluoro-2'-deoxyuridine. 69
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus 68
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus. 68
The defect of the Golgi GDP-L-fucose transporter IIc:effect on GDP-L-fucose metabolism. 68
Differential terminal fucosylation of N-Linked glycans versus protein O-Fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc) 68
Chlorella Virus PBCV-1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose 66
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus 66
Core fucosylation of glycoprotein in LAD II/CDGs IIc fibroblasts 65
Identification of a metabolic pathway able to convert dTDP-D-glucose to 6-deoxyhexoses in human cells 65
GDP-L-fucose metabolism in fibroblasts from LAD II/CDG IIc patients. 64
Interaction of carboplatin with carrier human erythrocytes 63
Le comunità di pratica presso l’Università di Genova: l’esperienza e le motivazioni dei partecipanti 63
The metabolism of 6-deoxhexoses in bacterial and animal cells 62
The chlorella virus PBCV-1 encodes two enzymes involved in the de novo synthesis of GDP-L-fucose. 61
Extracellular ATP enhances mRNA levels of nitric oxide synthase and TNF-a in lipopolysaccharide-treated RAW 264.7 murine macrophage 59
Glucose 6-phosphate dehydrogenase from human erythrocytes: identification of N-acetil-alanine at the N-terminus of the mature protein 59
Chlorovirus PBCV-1 protein A064R has three of the transferase activities necessary to synthesize its capsid protein N-linked glycans 58
Structural and enzymatic characterization of recombinant GDP-D-mannose dehydratase (GMD) from PBCV-1 virus. 57
Relationship between elevated FX expression and increased production of GDP-L-fucose, a common donor substrate for fucosylation in human hepatocellular carcinoma and hepatoma cell lines. 57
Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced b indoleamine 2,3-dioxgenase 57
Effects of microRNAs on fucosyltransferase 8 expressio in hepatocarcinoma cells 56
Analisi strutturale degli oligosaccaridi N-linked e O-linked contenenti fucoso nelle glicoproteine di pazienti affetti da sindrome LAD II 56
Interactions of carboplatin with human erythrocytes and murine erythroleukemic cells. 56
Identification of cis-diamminedichloroplatinum adducts with DNA by HPLC and mass Spectrometry 50
Il corso di formazione all’innovazione didattica universitaria (FOR.I.U.) dell’Università di Genova 43
Come avviare un programma di Faculty Development: l’esperienza dell’Università di Genova 38
Expanding the Occurrence of Polysaccharides to the Viral World: The Case of Mimivirus 28
Unraveling the pathogenic bases of Catel-Manzke syndrome using a zebrafish knock-out model 18
The L-Rhamnose Biosynthetic Pathway in Trichomonas vaginalis: Identification and Characterization of UDP-D-Glucose 4,6-dehydratase 15
Unveiling the GT114 family: Structural characterization of A075L, a glycosyltransferase from Paramecium bursaria chlorella virus-1 (PBCV-1) 1
The Astounding World of Glycans from Giant Viruses 1
Totale 8.436
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Categoria #
all - tutte 24.782
article - articoli 17.929
book - libri 0
conference - conferenze 4.882
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.971
Totale 49.564
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.328 0 0 0 0 0 0 288 96 174 395 250 125
2020/2021433 18 36 21 26 48 34 31 38 52 60 32 37
2021/20221.111 30 87 84 132 41 54 78 273 29 96 41 166
2022/20231.013 117 54 10 99 175 191 0 85 182 4 84 12
2023/2024471 27 89 17 48 38 91 25 27 15 8 17 69
2024/2025727 43 119 53 103 258 144 7 0 0 0 0 0
Totale 8.437