IRIS
SIGNORELLO, MARIA GRAZIA
 Distribuzione geografica
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Continente #
EU - Europa 4.856
Totale 4.856
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Nazione #
IT - Italia 4.856
Totale 4.856
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Città #
Genova 3.807
Rapallo 458
Genoa 438
Vado Ligure 147
Bordighera 6
Totale 4.856
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Nome #
Synthesis, in vitro antiplatelet activity and molecular modelling studies of 10-substituted 2-(1-piperazinyl)pyrimido[1,2-a]benzimidazol-4(10H)-ones 154
Homocysteine, reactive oxygen species and nitric oxide in type 2 diabetes mellitus 151
Hydrogen peroxide formation in platelets of patients with non-insulin-dependent diabetes mellitus 140
Extramitochondrial energy production in platelets 135
Mechanisms involved in the antiplatelet activity of 8-methyl-4-(1-piperazinyl)-7-(3-pyridinylmethoxy)-2H-1-benzopyran-2-one (RC414) 131
From pomegranate marcs to a potential bioactive ingredient: a recycling proposal for pomegranate squeezing marcs 128
Homocysteine decreases platelet NO level via protein kinase C activation 124
Hyperactivity and increased hydrogen peroxide formation in platelets of NIDDM patients 122
Activation of Human Platelets by 2-Arachidonoylglycerol: Role of PKC in NO/cGMP Pathway Modulation. 122
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation and comparative molecular field analysis 120
N-Ethylmaleimide inhibition of thrombin-induced platelet aggregation 119
N-Ethylmaleimide-stimulated arachidonic acid release in human platelets 118
Impaired L-arginine uptake in platelets from type 2 diabetic patients 117
Regulation of cAMP Intracellular Levels in Human Platelets Stimulated by 2-Arachidonoylglycerol 117
Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation 116
Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway 115
Effect of homocysteine on arachidonic acid release in human platelets 114
Activation of p38 MAPKinase / cPLA2 pathway in homocysteine treated platelets 114
Transport of L-arginine and nitric oxide formation in human platelets 113
Reactive oxygen species accumulation induced by homocysteine in human platelets 107
The molecular mechanisms involved in lectin-induced human platelet aggregation 107
The anandamide effect on NO/cGMP pathway in human platelets 106
In retinal vein occlusion platelet response to thrombin is increased 104
The L-arginine/NO pathway in the early phases of platelet stimulation by collagen 103
The arachidonic acid effect on platelet nitric oxide level 103
Modulation of L-arginine uptake and nitric oxide production by gabexate mesylate 98
Effect of 2-(1-Piperazinyl)-4H-pyrido[1,2-a] pyrimidin-4-one (AP155) on human platelets "in vitro" 97
Synthesis, antiplatelet activity and comparative molecular fields analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues 96
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site 96
The 2-arachidonoylglycerol effect on myosin light chain phosphorylation in human platelets 91
Microonde ed ultrasuoni: tecnologie green per lo sfruttamento e la valorizzazione degli scarti di produzione del succo di melograno 88
Effects of homocysteine on L-arginine transport and nitric oxide formation in human platelets 86
Mechanism of action of two new pyrimidoquinoline and isoquinoline derivatives in human platelets 86
Anandamide Induces Platelet Nitric Oxide Synthase through AMP-Activated Protein Kinase 85
Regulation of L-arginine uptake by Ca2+ in human platelets 84
Platelet activation by collagen is increased in retinal vein occlusion 81
Effect of 2-arachidonoylglycerol on myosin light chain phosphorylation and platelet activation: The role of phosphatidylinositol 3 kinase/AKT pathway 79
Reshaped as polyester-based nanoparticles, gallic acid inhibits platelet aggregation, reactive oxygen species production and multi-resistant Gram-positive bacteria with an efficiency never obtained 79
A role for PLCgamma2 in platelet activation by homocysteine 73
A recycling proposal for pomegranate marcs obtained after juice squeezing 67
Sinthesis in vitro inhibitory activity on human platelet aggregation of novel properly substituted 4-(1-piperazinyl)-coumarins 62
GREEN EXTRACTIONS FROM POMEGRANATE JUICE BY-PRODUCTS AND THEIR POTENTIAL USE AS NATURAL FOOD/COSMETIC PRESERVATIVES AND/OR BIOACTIVE INGREDIENTS 60
New Hybrid Pyrazole and Imidazopyrazole Antinflammatory Agents Able to Reduce ROS Production in Different Biological Targets 60
The Ca2+/calmodulin kinase/AMP-activated protein kinase pathway regulates the lectin phaseolus vulgaris agglutinin induced NO production in human platelets 58
Oxidative stress, homocysteine and platelet function in NIDDM patients 57
Activation of CaMKKbeta/AMPKalfa pathway by 2-AG in human platelets 57
FROM NANOTECHNOLOGY THE WAY TO IMPROVE THE MULTI-TARGET ACTIVITIES OF A NATURAL POLYPHENOL: A STUDY INVOLVING GALLIC ACID AND AN ESTER-TYPE BIODEGRADABLE DENDRIMER 55
Lectin-induced oxidative stress in human platelets 47
Insights into the Pharmacological Activity of the Imidazo-Pyrazole Scaffold 43
New series of pyrazoles and imidazo‐pyrazoles targeting different cancer and inflammation pathways 38
Synthesis and biological evaluation of new pyrazole carbohydrazides as antiproliferative and antioxidant agents. 37
Synthesis, Antiproliferative, and Antioxidant Properties of Highly Functionalized Pyrazoles 24
Scouting in silico different chemo-types of PDE4 inhibitors to guide the design of new anti-inflammatory/antioxidant agents 23
Investigations of Antioxidant and Anti-Cancer Activities of 5-Aminopyrazole Derivatives 19
Endocannabinoids effect on oxidative status of human platelets 12
Inside the Mechanism of Action of Three Pyrazole Derivatives in Human Platelets and Endothelial Cells 9
Erratum: Synthesis, antiplatelet activity and comparative molecular field analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues (Bioorganic and Medicinal Chemistry (2000) 8 (751) PII: S80968089600000109) 9
Modulation of L-arginine transport and nitric oxide production by gabexate mesylate 5
Synthesis, antiplatelet activity and comparative molecular field analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues 4
Platelet Metabolic Flexibility: A Matter of Substrate and Location 4
Oxidative Stress Induced by Cortisol in Human Platelets 1
The Remarkable and Selective In Vitro Cytotoxicity of Synthesized Bola-Amphiphilic Nanovesicles on Etoposide-Sensitive and -Resistant Neuroblastoma Cells 1
Totale 4.971
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Categoria #
all - tutte 14.477
article - articoli 13.082
book - libri 0
conference - conferenze 1.395
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.954
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.301 0 0 56 98 139 135 234 94 122 236 137 50
2020/2021461 32 46 24 33 21 91 24 41 49 48 17 35
2021/2022648 23 31 50 58 24 52 30 156 37 72 31 84
2022/2023550 44 51 3 69 71 86 3 44 95 7 64 13
2023/2024328 11 68 13 49 25 38 29 18 10 9 16 42
2024/2025191 76 91 24 0 0 0 0 0 0 0 0 0
Totale 4.971