SIGNORELLO, MARIA GRAZIA
 Distribuzione geografica
Continente #
EU - Europa 5.204
Totale 5.204
Nazione #
IT - Italia 5.204
Totale 5.204
Città #
Genova 3.807
Vado Ligure 495
Rapallo 458
Genoa 438
Bordighera 6
Totale 5.204
Nome #
Homocysteine, reactive oxygen species and nitric oxide in type 2 diabetes mellitus 162
Synthesis, in vitro antiplatelet activity and molecular modelling studies of 10-substituted 2-(1-piperazinyl)pyrimido[1,2-a]benzimidazol-4(10H)-ones 158
Hydrogen peroxide formation in platelets of patients with non-insulin-dependent diabetes mellitus 147
Extramitochondrial energy production in platelets 141
Mechanisms involved in the antiplatelet activity of 8-methyl-4-(1-piperazinyl)-7-(3-pyridinylmethoxy)-2H-1-benzopyran-2-one (RC414) 137
From pomegranate marcs to a potential bioactive ingredient: a recycling proposal for pomegranate squeezing marcs 134
Activation of Human Platelets by 2-Arachidonoylglycerol: Role of PKC in NO/cGMP Pathway Modulation. 131
Homocysteine decreases platelet NO level via protein kinase C activation 128
Hyperactivity and increased hydrogen peroxide formation in platelets of NIDDM patients 127
N-Ethylmaleimide inhibition of thrombin-induced platelet aggregation 126
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation and comparative molecular field analysis 125
Impaired L-arginine uptake in platelets from type 2 diabetic patients 123
N-Ethylmaleimide-stimulated arachidonic acid release in human platelets 123
Regulation of cAMP Intracellular Levels in Human Platelets Stimulated by 2-Arachidonoylglycerol 122
Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation 122
Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway 120
Effect of homocysteine on arachidonic acid release in human platelets 118
Activation of p38 MAPKinase / cPLA2 pathway in homocysteine treated platelets 118
Transport of L-arginine and nitric oxide formation in human platelets 117
Reactive oxygen species accumulation induced by homocysteine in human platelets 112
The molecular mechanisms involved in lectin-induced human platelet aggregation 112
The arachidonic acid effect on platelet nitric oxide level 111
In retinal vein occlusion platelet response to thrombin is increased 110
The anandamide effect on NO/cGMP pathway in human platelets 110
The L-arginine/NO pathway in the early phases of platelet stimulation by collagen 107
Effect of 2-(1-Piperazinyl)-4H-pyrido[1,2-a] pyrimidin-4-one (AP155) on human platelets "in vitro" 103
Modulation of L-arginine uptake and nitric oxide production by gabexate mesylate 102
Synthesis, antiplatelet activity and comparative molecular fields analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues 101
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site 101
The 2-arachidonoylglycerol effect on myosin light chain phosphorylation in human platelets 96
Microonde ed ultrasuoni: tecnologie green per lo sfruttamento e la valorizzazione degli scarti di produzione del succo di melograno 96
Mechanism of action of two new pyrimidoquinoline and isoquinoline derivatives in human platelets 90
Anandamide Induces Platelet Nitric Oxide Synthase through AMP-Activated Protein Kinase 90
Effects of homocysteine on L-arginine transport and nitric oxide formation in human platelets 89
Regulation of L-arginine uptake by Ca2+ in human platelets 88
Reshaped as polyester-based nanoparticles, gallic acid inhibits platelet aggregation, reactive oxygen species production and multi-resistant Gram-positive bacteria with an efficiency never obtained 87
Platelet activation by collagen is increased in retinal vein occlusion 86
Effect of 2-arachidonoylglycerol on myosin light chain phosphorylation and platelet activation: The role of phosphatidylinositol 3 kinase/AKT pathway 84
A role for PLCgamma2 in platelet activation by homocysteine 79
A recycling proposal for pomegranate marcs obtained after juice squeezing 73
New Hybrid Pyrazole and Imidazopyrazole Antinflammatory Agents Able to Reduce ROS Production in Different Biological Targets 67
Sinthesis in vitro inhibitory activity on human platelet aggregation of novel properly substituted 4-(1-piperazinyl)-coumarins 65
GREEN EXTRACTIONS FROM POMEGRANATE JUICE BY-PRODUCTS AND THEIR POTENTIAL USE AS NATURAL FOOD/COSMETIC PRESERVATIVES AND/OR BIOACTIVE INGREDIENTS 65
Activation of CaMKKbeta/AMPKalfa pathway by 2-AG in human platelets 65
The Ca2+/calmodulin kinase/AMP-activated protein kinase pathway regulates the lectin phaseolus vulgaris agglutinin induced NO production in human platelets 63
Oxidative stress, homocysteine and platelet function in NIDDM patients 62
FROM NANOTECHNOLOGY THE WAY TO IMPROVE THE MULTI-TARGET ACTIVITIES OF A NATURAL POLYPHENOL: A STUDY INVOLVING GALLIC ACID AND AN ESTER-TYPE BIODEGRADABLE DENDRIMER 60
Lectin-induced oxidative stress in human platelets 55
Insights into the Pharmacological Activity of the Imidazo-Pyrazole Scaffold 52
New series of pyrazoles and imidazo‐pyrazoles targeting different cancer and inflammation pathways 42
Synthesis and biological evaluation of new pyrazole carbohydrazides as antiproliferative and antioxidant agents. 40
Synthesis, Antiproliferative, and Antioxidant Properties of Highly Functionalized Pyrazoles 37
Investigations of Antioxidant and Anti-Cancer Activities of 5-Aminopyrazole Derivatives 31
Scouting in silico different chemo-types of PDE4 inhibitors to guide the design of new anti-inflammatory/antioxidant agents 27
Inside the Mechanism of Action of Three Pyrazole Derivatives in Human Platelets and Endothelial Cells 17
Endocannabinoids effect on oxidative status of human platelets 16
Erratum: Synthesis, antiplatelet activity and comparative molecular field analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues (Bioorganic and Medicinal Chemistry (2000) 8 (751) PII: S80968089600000109) 13
Platelet Metabolic Flexibility: A Matter of Substrate and Location 8
Modulation of L-arginine transport and nitric oxide production by gabexate mesylate 8
Synthesis, antiplatelet activity and comparative molecular field analysis of substituted 2-amino-4H-pyrido[1,2-a]pyrimidin-4-ones, their congeners and isosteric analogues 7
Structure–Activity Relationship Studies on Highly Functionalized Pyrazole Hydrazones and Amides as Antiproliferative and Antioxidant Agents 7
The Remarkable and Selective In Vitro Cytotoxicity of Synthesized Bola-Amphiphilic Nanovesicles on Etoposide-Sensitive and -Resistant Neuroblastoma Cells 7
Oxidative Stress Induced by Cortisol in Human Platelets 5
Totale 5.325
Categoria #
all - tutte 15.879
article - articoli 14.326
book - libri 0
conference - conferenze 1.553
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.758


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.008 0 0 0 0 0 135 234 94 122 236 137 50
2020/2021461 32 46 24 33 21 91 24 41 49 48 17 35
2021/2022648 23 31 50 58 24 52 30 156 37 72 31 84
2022/2023550 44 51 3 69 71 86 3 44 95 7 64 13
2023/2024328 11 68 13 49 25 38 29 18 10 9 16 42
2024/2025545 76 91 31 71 165 111 0 0 0 0 0 0
Totale 5.325