IRIS
MATTIOLI, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 10.335
Totale 10.335
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Nazione #
IT - Italia 10.335
Totale 10.335
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Città #
Genova 8.109
Rapallo 1.208
Genoa 987
Bordighera 30
Totale 10.334
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Nome #
An Artificial aqueous humor as a standard matrix to assess drug concentration in the anterior chamber by High Performance Liquid Chromatography methods 250
Effetto citotossico su fibroblasti L929 di estratti grezzi di alghe fitoplanctoniche (Chlorella minutissima e Pseudokirchneriella subcapitata). 188
Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects 157
1,5-Benzodiazepines IX. A new route to substituted 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amines with analgesic and/or anti-inflammatory activities 151
Splanchnic haemodynamic effects of ketanserin in anaesthetized cirrhotic rats. 146
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors 145
Formation of DNA-damaging N-nitroso compounds from the interaction of calcium-channel blockers with nitrite 142
Aromatic Schiff bases and 2,3-disubstituted-1,3-thiazolidin-4one derivatives as anti-inflammatory agents 139
HPLC determination of malondialdehyde as biomarker for oxidative stress: application in patients with alcohol dependence. 139
Population pharmacokinetics and probability of target attainment of meropenem in critically ill patients 138
Testing of metoclopramide and procainamide for their ability to induce genotoxic effects in cultured mammalian cells. 134
1-Phenyl-1H-Indazole derivatives with analgesic and anti-inflammatory activities. 132
DNA damage in peripheral blood lymphocytes of patients with cirrhosis related to alcohol abuse or to hepatitis B and C viruses 130
Determination of deferasirox plasma concentrations: do gender, physical and genetic differences affect chelation efficacy? 129
Heparin-induced acute adverse reaction - case report of a patient with acute trauma and a genetic predisposition to thrombotic events: a concurrence of events 129
Comparative study of DNA repair induced by cyproterone acetate, chlormadinone acetate and megestrol acetate in primary cultures of human and rat hepatocytes. 127
Studies on genotoxicity and carcinogenicity of antibacterial, antiviral, antimalarial and antifungal drugs. 127
Systemic absorption and pharmacokinetics of single-dose early intravesical mitomycin C after transurethral resection of non-muscle invasive bladder cancer. 127
Clinical experience about an unexpected adverse event during nalmefene treatment in two patients with alcohol use disorder 126
Bromfenac ophthalmic solution 0.09 %: human aqueous humor concentration detected by high-performance liquid chromatography 125
4-Dialkylamino-1-(5-substituted or unsubstituted 1-phenyl-1H-pyrazol-4-yl)butan-1-ols: synthesis and evaluation of analgesic, anti-inflammatory and platelet anti-aggregating activities 122
Measurement of sorafenib plasma concentration by high-performance liquid chromatography in patients with advanced hepatocellular carcinoma: is it useful the application in clinical practice? A pilot study 122
In Vitro culture of human thyroid cells: preliminary findings on the role of the pathological condition of the donors. 122
1,8-Naphthyridines IV. 9-substituted N,N-dialkyl-5-(alkylamino or cycloalkylamino) [1,2,4]triazolo[4,3-a][1, 8]naphthyridine-6-carboxamides, new compounds with anti-aggressive and potent anti-inflammatory activities 121
A case report on escitalopram-induced hyperglycaemia in a diabetic patient. 121
Synthesis of 5-substituted 1-aryl-1H-pyrazole-4-acetonitriles, 4-methyl-1-phenyl-1H-pyrazole-3-carbonitrile and pharmacologically active 1-aryl-1H-pyrazole-4-acetic acids. 120
A possible medium-term assay for detecting the effects of liver and colon carcinogens in rats. 120
Genotoxicity testing of chloramphenicol in rodent and human cells 119
Update of carcinogenicity studies in animals and humans of 535 marketed pharmaceuticals 118
Penetration of oral cefuroxime axetil into the human aqueous humor. 117
DNA repair synthesis and DNA fragmentation in primary cultures of human and rat hepatocytes exposed to cyproterone acetate. 117
Interindividual variability in the absorption of ciprofloxacin and hydrocortisone from continent ileal reservoir for urine 117
Effects of reduced glutathione and n-acetylcysteine on lidocaine metabolism in cimetidine treated rats 115
Severe fluoropyrimidine-related toxicity: clinical implications of DPYD analysis and UH2/U ratio evaluation 114
Paliperidone for the treatment of ketamine-induced psychosis: a case report. 114
1,8-Naphthyridines II. 2,4-Disubstituted N,N-dialkyl-1,8-naphthyridine-3-carboxamides with anti-inflammatory and/or antiaggressive activities 112
Efficacy and tolerability of long-term oral cefaclor therapy in the prevention of urinary tract infections in infants and children 112
Use of human thyroid cell primary cultures for genotoxicity studies 111
Antiinflammatory and antinociceptive activities of some benzotriazolylalkanoic acids 110
Species, sex and inter-individual differences in DNA repair induced by nine sex steroids in primary cultures of rat and human hepatocytes 110
1,8-Naphthyridines VI. Synthesis and anti-inflammatory activity of 5-(alkylamino)-N,N-diethyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6 carboxamides with a new substitution pattern on the triazole ring 110
Approval rating and opinion of outpatients and general practitioners toward generic drugs: a questionnaire-based real-world study 108
Meropenem for treating KPC-producing Klebsiella pneumoniae bloodstream infections: should we get to the PK/PD root of the paradox? 107
Genotoxicity and carcinogenicity studies of antihistamines. 106
Studies on the mechanism of the carcinogenic activity of amitrole 106
What is known about deferasirox chelation therapy in pediatric HSCT recipients: two case reports of metabolic acidosis 105
Isfet-based biosensor modeling with spice. 104
DNA damage induced by 3,3’-dimethoxybenzidine in liver and urinary bladder cells of rats and humans 103
Genotoxicity testing of potassium canrenoate in cultured rat and human cells 102
A retrospective study showing the misuse of prophylactic antibiotics in patients undergoing appendicectomy and cholecystectomy 101
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid 99
Genotoxicity and carcinogenicity studies of bronchodilators and antiasthma drugs 99
Serum lamivudine levels in the presence of a lamivudine-resistant HBV mutant 98
Involvement of the mu-opioid receptor gene polymorphism A118G in the efficacy of detoxification of alcohol dependent patients. 98
Comparison of the sensitivity of human and rat hepatocytes to genotoxic effects of metronidazole 97
Low plasma cefaclor levels in cystectomized bladder cancer patients with various types of urinary diversion 96
Could Smokers’ Socio-Demographic and Housing Factors Affect and Influence the Choice Between Smoking Cessation Therapies? 96
Testing of p-dichlorobenzene and hexachlorobenzene for their ability to induce DNA damage and micronucleus formation in primary cultures of rat and human hepatocytes. 95
Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays 95
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by four rat thyroid carcinogens 95
Genotoxic and carcinogenic effects of gastrointestinal drugs 95
Intravesical gemcitabine in superficial bladder cancer: a phase II safety, efficacy and pharmacokinetic study 95
A silicon-based biosensor for real-time toxicity testing in normal versus cancer liver cells 95
A UHPLC–MS/MS method for the quantification of Δ9-tetrahydrocannabinol and cannabidiol in decoctions and in plasma samples for therapeutic monitoring of medical cannabis 92
Combined evaluation of genotype and phenotype of thiopurine S-methyltransferase (TPMT) in the clinical management of patients in chronic therapy with azathioprine 92
Codeine Precipitating Serotonin Syndrome in a Patient in Therapy with Antidepressant and Triptan 88
Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes 87
Introduzione alle colture cellulari 86
Uncommon Serum Creatine Phosphokinase and Lactic Dehydrogenase Increase during Diosmin Therapy 86
4-Substituted 1,5-diarylpyrazoles, analogues of celecoxib: synthesis and preliminary evaluation of biological properties 84
CT of the abdomen: Degree and quality of enhancement obtainedwith two concentrations of the same iodinated contrast medium withfixed iodine delivery rate and total iodine load 83
5-Substituted 4-Isoxazoleacetic acids with analgesic activity. 82
DNA damage induced by 4,4'-methylenedianiline in primary cultures of hepatocytes and thyreocytes from rats and humens 80
β-2 Agonists as Misusing Drugs? Assessment of both Clenbuterol- and Salbutamol-related European Medicines Agency Pharmacovigilance Database Reports 77
DNA fragmentation by 2-nitropropane in rat tissues, and effects of the modulation of biotransformation processes. 75
Studies on alpha-hexachlorocyclohexane cytotoxicity, genotoxicity and cytochrome P450 induction in primary hepatocytes and hepatoma cell lines from rodents and humans 75
Systemic Absorption and Pharmacokinetics of Single-dose Intravesical Gemcitabine After Transurethral Resection of the Bladder in Non-muscle-invasive Bladder Cancer 75
Co-Occurring Psychiatric and Substance Use Disorders: Clinical Survey Among a Rural Cohort of Italian Patients 74
Inhibitory properties of triethylphenosphine goldlupinylsulfide in adjuvant-induced arthritis in rats 73
Evaluation of auramine genotoxicity in primary rat and human hepatocytes and in the intact rat. 73
Active pharmacovigilance program in patients affected by psoriasis and inflammatory bowel diseases
 73
DNA fragmentation, DNA repair and apoptosis induced in primary rat hepatocytes by dienogest, dydrogesterone and 1,4,6-androstatriene-17beta-ol-3-one acetate 72
Safety and tolerability of deferasirox in pediatric hematopoietic stem cell transplant recipients: one facility's five years' experience of chelation treatment 72
Genotoxic and carcinogenic effects of antipsycotics and antidepressants 68
Genotoxicity and carcinogenicity testing of pharmaceuticals: Correlations between induction of DNA lesions and carcinogenic activity 68
Systemic Absorption and Pharmacokinetics of Single-Dose, Post-TURB (Trans-Urethral Resection of Bladder), Intravesical Gemcitabine, in Non-Muscle Invasive Bladder Cancer. 67
Assessment of Intestinal Permeability Using Sugar Probes: Influence of Urinary Volume 66
Introduzione alle colture cellulari. II edizione. 65
Cannabidiol determination on peripheral capillary blood using a microsampling method and ultra-high-performance liquid chromatography tandem mass spectrometry with on-line sample preparation 63
Pharmacokinetics and toxicity of an early single intravesical instillation of gemcitabine after endoscopic resection of superficial bladder cancer 62
α-Hexachlorocyclohexane: different frequency of DNA breaks in primary cultures and established line of human and rodent hepatocytes. 62
omega-Dialkylaminoalkil Ethers of Phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with Analgesic and Anti-inflammatory Activity 61
DNA damage in tissues of rat treated with potassium canrenoate 60
Pharmacokinetics of high-dose extended-infusion meropenem during pulmonary exacerbation in adult cystic fibrosis patients: a case series 59
1,8-Naphthyridines III. N,N-Dialkyl-5-chloro[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamides with anti-inflammatory activity 58
Genotoxic effects of alfa-hexachlorocyclohexane in primary cultures of rodents and human hepatocytes 54
In vitro and in vivo testing of hydralazine genotoxicity. 49
Intravesical Chemotherapy and Chemohyperthermia in Non-Muscle-Invasive Bladder Cancer; An Overview on Drug Administration Technologies and Pharmacokinetics 49
Shock emorragico in un politraumatizzato. Spunto per una proposta di linea guida per l’uso clinico di albumina 44
Evaluation of Pharmacokinetics and Pharmacodynamics of Deferasirox in Pediatric Patients 37
Totale 10.111
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Categoria #
all - tutte 28.762
article - articoli 27.595
book - libri 414
conference - conferenze 295
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 458
Totale 57.524
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019565 0 0 0 0 0 0 0 0 0 114 243 208
2019/20202.836 120 78 127 175 247 304 441 185 257 458 347 97
2020/2021818 49 101 63 80 43 70 25 77 63 119 57 71
2021/20221.444 49 133 111 125 61 70 94 331 92 129 78 171
2022/20231.480 145 108 15 176 215 228 4 135 240 24 161 29
2023/2024785 35 99 24 152 89 190 51 53 43 49 0 0
Totale 10.584