IRIS
MATTIOLI, FRANCESCA
 Distribuzione geografica
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Continente #
EU - Europa 11.817
Totale 11.817
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Nazione #
IT - Italia 11.817
Totale 11.817
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Città #
Genova 8.109
Genoa 1.283
Rapallo 1.208
Vado Ligure 1.186
Bordighera 30
Totale 11.816
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Nome #
An Artificial aqueous humor as a standard matrix to assess drug concentration in the anterior chamber by High Performance Liquid Chromatography methods 265
Effetto citotossico su fibroblasti L929 di estratti grezzi di alghe fitoplanctoniche (Chlorella minutissima e Pseudokirchneriella subcapitata). 219
Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects 202
1,5-Benzodiazepines IX. A new route to substituted 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amines with analgesic and/or anti-inflammatory activities 161
Population pharmacokinetics and probability of target attainment of meropenem in critically ill patients 156
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors 156
Clinical experience about an unexpected adverse event during nalmefene treatment in two patients with alcohol use disorder 154
Aromatic Schiff bases and 2,3-disubstituted-1,3-thiazolidin-4one derivatives as anti-inflammatory agents 153
Splanchnic haemodynamic effects of ketanserin in anaesthetized cirrhotic rats. 152
HPLC determination of malondialdehyde as biomarker for oxidative stress: application in patients with alcohol dependence. 151
Meropenem for treating KPC-producing Klebsiella pneumoniae bloodstream infections: should we get to the PK/PD root of the paradox? 149
Formation of DNA-damaging N-nitroso compounds from the interaction of calcium-channel blockers with nitrite 148
1-Phenyl-1H-Indazole derivatives with analgesic and anti-inflammatory activities. 143
Determination of deferasirox plasma concentrations: do gender, physical and genetic differences affect chelation efficacy? 142
Testing of metoclopramide and procainamide for their ability to induce genotoxic effects in cultured mammalian cells. 141
Heparin-induced acute adverse reaction - case report of a patient with acute trauma and a genetic predisposition to thrombotic events: a concurrence of events 140
DNA damage in peripheral blood lymphocytes of patients with cirrhosis related to alcohol abuse or to hepatitis B and C viruses 140
Systemic absorption and pharmacokinetics of single-dose early intravesical mitomycin C after transurethral resection of non-muscle invasive bladder cancer. 136
Comparative study of DNA repair induced by cyproterone acetate, chlormadinone acetate and megestrol acetate in primary cultures of human and rat hepatocytes. 135
A case report on escitalopram-induced hyperglycaemia in a diabetic patient. 135
Bromfenac ophthalmic solution 0.09 %: human aqueous humor concentration detected by high-performance liquid chromatography 135
A possible medium-term assay for detecting the effects of liver and colon carcinogens in rats. 134
Studies on genotoxicity and carcinogenicity of antibacterial, antiviral, antimalarial and antifungal drugs. 134
4-Dialkylamino-1-(5-substituted or unsubstituted 1-phenyl-1H-pyrazol-4-yl)butan-1-ols: synthesis and evaluation of analgesic, anti-inflammatory and platelet anti-aggregating activities 133
Measurement of sorafenib plasma concentration by high-performance liquid chromatography in patients with advanced hepatocellular carcinoma: is it useful the application in clinical practice? A pilot study 132
1,8-Naphthyridines IV. 9-substituted N,N-dialkyl-5-(alkylamino or cycloalkylamino) [1,2,4]triazolo[4,3-a][1, 8]naphthyridine-6-carboxamides, new compounds with anti-aggressive and potent anti-inflammatory activities 130
DNA repair synthesis and DNA fragmentation in primary cultures of human and rat hepatocytes exposed to cyproterone acetate. 129
In Vitro culture of human thyroid cells: preliminary findings on the role of the pathological condition of the donors. 129
Synthesis of 5-substituted 1-aryl-1H-pyrazole-4-acetonitriles, 4-methyl-1-phenyl-1H-pyrazole-3-carbonitrile and pharmacologically active 1-aryl-1H-pyrazole-4-acetic acids. 127
Effects of reduced glutathione and n-acetylcysteine on lidocaine metabolism in cimetidine treated rats 126
Use of human thyroid cell primary cultures for genotoxicity studies 126
Genotoxicity testing of chloramphenicol in rodent and human cells 125
Paliperidone for the treatment of ketamine-induced psychosis: a case report. 124
Interindividual variability in the absorption of ciprofloxacin and hydrocortisone from continent ileal reservoir for urine 124
Update of carcinogenicity studies in animals and humans of 535 marketed pharmaceuticals 124
1,8-Naphthyridines II. 2,4-Disubstituted N,N-dialkyl-1,8-naphthyridine-3-carboxamides with anti-inflammatory and/or antiaggressive activities 123
Severe fluoropyrimidine-related toxicity: clinical implications of DPYD analysis and UH2/U ratio evaluation 123
Penetration of oral cefuroxime axetil into the human aqueous humor. 122
Antiinflammatory and antinociceptive activities of some benzotriazolylalkanoic acids 121
Approval rating and opinion of outpatients and general practitioners toward generic drugs: a questionnaire-based real-world study 121
1,8-Naphthyridines VI. Synthesis and anti-inflammatory activity of 5-(alkylamino)-N,N-diethyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6 carboxamides with a new substitution pattern on the triazole ring 121
Efficacy and tolerability of long-term oral cefaclor therapy in the prevention of urinary tract infections in infants and children 117
Species, sex and inter-individual differences in DNA repair induced by nine sex steroids in primary cultures of rat and human hepatocytes 117
What is known about deferasirox chelation therapy in pediatric HSCT recipients: two case reports of metabolic acidosis 114
Studies on the mechanism of the carcinogenic activity of amitrole 113
A retrospective study showing the misuse of prophylactic antibiotics in patients undergoing appendicectomy and cholecystectomy 111
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid 111
Genotoxicity and carcinogenicity studies of antihistamines. 111
DNA damage induced by 3,3’-dimethoxybenzidine in liver and urinary bladder cells of rats and humans 110
Genotoxicity testing of potassium canrenoate in cultured rat and human cells 109
Isfet-based biosensor modeling with spice. 109
A silicon-based biosensor for real-time toxicity testing in normal versus cancer liver cells 108
Involvement of the mu-opioid receptor gene polymorphism A118G in the efficacy of detoxification of alcohol dependent patients. 107
Genotoxicity and carcinogenicity studies of bronchodilators and antiasthma drugs 107
Comparison of the sensitivity of human and rat hepatocytes to genotoxic effects of metronidazole 106
DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by four rat thyroid carcinogens 105
Serum lamivudine levels in the presence of a lamivudine-resistant HBV mutant 104
Genotoxic and carcinogenic effects of gastrointestinal drugs 104
Intravesical gemcitabine in superficial bladder cancer: a phase II safety, efficacy and pharmacokinetic study 104
Could Smokers’ Socio-Demographic and Housing Factors Affect and Influence the Choice Between Smoking Cessation Therapies? 104
Low plasma cefaclor levels in cystectomized bladder cancer patients with various types of urinary diversion 103
Codeine Precipitating Serotonin Syndrome in a Patient in Therapy with Antidepressant and Triptan 103
A UHPLC–MS/MS method for the quantification of Δ9-tetrahydrocannabinol and cannabidiol in decoctions and in plasma samples for therapeutic monitoring of medical cannabis 102
Combined evaluation of genotype and phenotype of thiopurine S-methyltransferase (TPMT) in the clinical management of patients in chronic therapy with azathioprine 102
Testing of p-dichlorobenzene and hexachlorobenzene for their ability to induce DNA damage and micronucleus formation in primary cultures of rat and human hepatocytes. 101
Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays 101
4-Substituted 1,5-diarylpyrazoles, analogues of celecoxib: synthesis and preliminary evaluation of biological properties 99
Uncommon Serum Creatine Phosphokinase and Lactic Dehydrogenase Increase during Diosmin Therapy 97
Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes 96
Introduzione alle colture cellulari 95
5-Substituted 4-Isoxazoleacetic acids with analgesic activity. 93
CT of the abdomen: Degree and quality of enhancement obtainedwith two concentrations of the same iodinated contrast medium withfixed iodine delivery rate and total iodine load 91
β-2 Agonists as Misusing Drugs? Assessment of both Clenbuterol- and Salbutamol-related European Medicines Agency Pharmacovigilance Database Reports 90
Co-Occurring Psychiatric and Substance Use Disorders: Clinical Survey Among a Rural Cohort of Italian Patients 86
Active pharmacovigilance program in patients affected by psoriasis and inflammatory bowel diseases
 85
DNA damage induced by 4,4'-methylenedianiline in primary cultures of hepatocytes and thyreocytes from rats and humens 84
Inhibitory properties of triethylphenosphine goldlupinylsulfide in adjuvant-induced arthritis in rats 83
Studies on alpha-hexachlorocyclohexane cytotoxicity, genotoxicity and cytochrome P450 induction in primary hepatocytes and hepatoma cell lines from rodents and humans 83
Safety and tolerability of deferasirox in pediatric hematopoietic stem cell transplant recipients: one facility's five years' experience of chelation treatment 83
DNA fragmentation, DNA repair and apoptosis induced in primary rat hepatocytes by dienogest, dydrogesterone and 1,4,6-androstatriene-17beta-ol-3-one acetate 81
Evaluation of auramine genotoxicity in primary rat and human hepatocytes and in the intact rat. 81
Systemic Absorption and Pharmacokinetics of Single-dose Intravesical Gemcitabine After Transurethral Resection of the Bladder in Non-muscle-invasive Bladder Cancer 81
Pharmacokinetics of high-dose extended-infusion meropenem during pulmonary exacerbation in adult cystic fibrosis patients: a case series 81
DNA fragmentation by 2-nitropropane in rat tissues, and effects of the modulation of biotransformation processes. 80
Pharmacokinetics and toxicity of an early single intravesical instillation of gemcitabine after endoscopic resection of superficial bladder cancer 80
Introduzione alle colture cellulari. II edizione. 78
Assessment of Intestinal Permeability Using Sugar Probes: Influence of Urinary Volume 78
Genotoxic and carcinogenic effects of antipsycotics and antidepressants 75
Genotoxicity and carcinogenicity testing of pharmaceuticals: Correlations between induction of DNA lesions and carcinogenic activity 73
Systemic Absorption and Pharmacokinetics of Single-Dose, Post-TURB (Trans-Urethral Resection of Bladder), Intravesical Gemcitabine, in Non-Muscle Invasive Bladder Cancer. 73
α-Hexachlorocyclohexane: different frequency of DNA breaks in primary cultures and established line of human and rodent hepatocytes. 71
1,8-Naphthyridines III. N,N-Dialkyl-5-chloro[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamides with anti-inflammatory activity 69
Cannabidiol determination on peripheral capillary blood using a microsampling method and ultra-high-performance liquid chromatography tandem mass spectrometry with on-line sample preparation 68
omega-Dialkylaminoalkil Ethers of Phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with Analgesic and Anti-inflammatory Activity 65
DNA damage in tissues of rat treated with potassium canrenoate 64
Intravesical Chemotherapy and Chemohyperthermia in Non-Muscle-Invasive Bladder Cancer; An Overview on Drug Administration Technologies and Pharmacokinetics 63
Genotoxic effects of alfa-hexachlorocyclohexane in primary cultures of rodents and human hepatocytes 59
In vitro and in vivo testing of hydralazine genotoxicity. 54
Shock emorragico in un politraumatizzato. Spunto per una proposta di linea guida per l’uso clinico di albumina 52
Erythrocytes cell wall defects correlate with the stage of liver cirrhosis 47
Totale 11.162
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Categoria #
all - tutte 38.235
article - articoli 36.418
book - libri 561
conference - conferenze 586
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 670
Totale 76.470
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.785 0 0 0 0 0 0 441 185 257 458 347 97
2020/2021818 49 101 63 80 43 70 25 77 63 119 57 71
2021/20221.444 49 133 111 125 61 70 94 331 92 129 78 171
2022/20231.480 145 108 15 176 215 228 4 135 240 24 161 29
2023/2024988 35 99 23 151 89 188 50 53 43 53 63 141
2024/20251.292 98 217 99 179 355 332 12 0 0 0 0 0
Totale 12.079