IRIS
AVERNA, MONICA
 Distribuzione geografica
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Continente #
EU - Europa 6.900
Totale 6.900
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Nazione #
IT - Italia 6.900
Totale 6.900
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Città #
Genova 5.450
Rapallo 772
Genoa 668
Bordighera 10
Totale 6.900
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 154
Role of the calpain-calpastatin system in the density-dependent growth arrest 149
A2A-D2 heteromers on striatal astrocytes: Biochemical and biophysical evidence 147
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 146
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 145
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 143
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 142
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 138
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 138
Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle. 137
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 133
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 130
Pathological role of the calpain/calpastatin system in cystic fibrosis 126
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 126
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 125
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 125
Calpain-1 resident in lipid raft/caveolin-1 membrane microdomains plays a protective role in endothelial cells. 125
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 124
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 122
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 120
A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation 119
Acyl-CoA-binding protein is a potent m-calpain activator 115
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 112
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 111
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 111
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 110
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 110
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 110
Role of calpain-1 in the early phase of experimental ALS 109
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 108
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 105
“Susceptibility of NOS isoforms to calpain digestion is modulated by the expression levels of HSP90” 103
Changes in intracellular localization of calpastatin during calpain activation 101
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 96
Role of the regulatory domain of calpastatin in the autoproteolytic activation of calpain 96
Age-dependent degradation of calpastatin in kidney of hypertensive rats 96
Is the Expression of [-G93A(+)] human SOD1 a model to study neurodegenerations? 93
Phosphorylation of rat brain calpastatins by protein kinase C. 90
In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS-HSP90 heterocomplex 88
Calpain-mediated activation of NO synthase in human neuroblastoma SK-N-BE cells 86
"Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease?" 84
Modulation of rat brain calpastatin efficiency by post-translational modifications 82
Differential degradation of calpastatin by mu- and m-calpain in Ca(2+)-enriched human neuroblastoma LAN-5 cells. 81
Properties of calpastatin forms in rat brain 79
Cytosolic levels of calpastatin are regulated by limited proteolysis 79
Regulation of the calpain-calpastatin system in rat brain during alteration of Ca2+ homeostasis 78
“Involvement of the Calpain/Calpastatin System in Familial Amyotrophic Lateral Sclerosis” 75
Activation of calpain 1 and protein kinase C alpha promotes a constitutive expression and release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 75
Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis 73
"Cytosolic levels of calpastatin are regulated by limited proteolysis" 72
A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation 72
“How is alteration in Ca2+ homeostasis controlled in brain? A role for calpastatin” 71
Production and purification of recombinant calpastatin 71
“Regulation of calpain activity in brain following altered Ca2+ homeostasis” 69
A Novel signalling mechanism promoting Ca(2+) driven cell responses through high-mobility group box-1/NMDA receptor interaction. 68
Isolation of endogenous calpastatin 67
Bioactive molecules isolated from olive pomace extract protect cells from calcium mediated damages 66
"Intracellular calpastatin proteolysis: a salvage mechanism or a prelude to cell damage?" 61
Principi di biochimica 61
Specific role of calpain-1 associated to N-methy l-D-aspartate receptor in lipid rafts microdomains 59
Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease? 58
Interaction between catalitically inactive calpain and calpastatin: evidence for its occurrence in stimulated cells 56
Immunoblotting for calpastatin expression 56
Biochemical and biophysical evidence for the A2A-D2 heteroreceptors in striatal astrocytes 55
Biochimica 53
“Entry in the quiescent G0 cell state requires enhanced calpain activation” 52
Functional role of HSP90 complexes with endothelial nitric-oxide synthase (eNOS) and calpain on nitric oxide generation in endothelial cells 52
Heteromerization of Dopamine D2 and Oxytocin Receptor in Adult Striatal Astrocytes 51
Homozygous familial hypercholesterolemia in Italy: Clinical and molecular features 51
The calpain-calpastatin system in human central nervous system tumours: new insight on its prognostic value 50
Heterodimer of A2A and Oxytocin Receptors Regulating Glutamate Release in Adult Striatal Astrocytes 41
A2A-D2 heteromerization on striatal astrocytes: evidence and modulation of glutamate release 39
Identification of potential leukocyte biomarkers related to drug recovery of cftr: Clinical applications in cystic fibrosis 39
Reactive astrocytosis in a mouse model of chronic polyamine catabolism activation 39
Long-term efficacy of lipoprotein apheresis and lomitapide in the treatment of homozygous familial hypercholesterolemia (HoFH): a cross-national retrospective survey 27
Revisiting the role of leukocytes in cystic fibrosis 25
Reported muscle symptoms during statin treatment amongst Italian dyslipidaemic patients in the real-life setting: the PROSISA Study 20
The Involvement of Polyamines Catabolism in the Crosstalk between Neurons and Astrocytes in Neurodegeneration 17
A2A and Oxytocin receptor heteromers: exploring their role as modulators of glutamate release in adult striatal astrocytes 16
Dysmetabolism of Polyamines in a Transgenic Mouse Model Overexpressing Spermine Oxidase in Cerebrocortical Neurons: Reactive Astrocytosis and Neuronal Suffering 14
Reactive Astrocytosis in a Mouse Model of Chronic Polyamine Catabolism Activation 12
Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization 9
Temperature-Dependent Olive Pomace Extraction for Obtaining Bioactive Compounds Preventing the Death of Murine Cortical Neurons 8
Modulation of Plasmatic Matrix Metalloprotease 9: A Promising New Tool for Understanding the Variable Clinical Responses of Patients with Cystic Fibrosis to Cystic Fibrosis Transmembrane Conductance Regulator Modulators 7
OTR-D2 heterodimerization in striatal astrocytes: biochemical and biophysical evidence 5
Totale 7.059
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Categoria #
all - tutte 18.922
article - articoli 13.414
book - libri 376
conference - conferenze 4.686
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 446
Totale 37.844
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019406 0 0 0 0 0 0 0 0 0 78 173 155
2019/20202.025 105 58 107 141 190 205 272 142 169 315 248 73
2020/2021526 31 48 41 51 34 37 21 53 38 88 39 45
2021/2022951 30 55 82 71 39 58 63 219 48 98 41 147
2022/2023944 74 70 15 118 109 148 3 51 166 18 153 19
2023/2024528 33 65 17 94 66 148 30 26 40 9 0 0
Totale 7.059