IRIS
AVERNA, MONICA
 Distribuzione geografica
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Continente #
EU - Europa 7.383
Totale 7.383
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Nazione #
IT - Italia 7.383
Totale 7.383
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Città #
Genova 5.450
Genoa 923
Rapallo 772
Vado Ligure 228
Bordighera 10
Totale 7.383
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 160
A2A-D2 heteromers on striatal astrocytes: Biochemical and biophysical evidence 153
Role of the calpain-calpastatin system in the density-dependent growth arrest 152
Clinical Severity of β-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System. 151
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 150
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 150
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 145
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 145
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 144
Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle. 141
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 139
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 135
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 132
Calpain-1 resident in lipid raft/caveolin-1 membrane microdomains plays a protective role in endothelial cells. 131
Pathological role of the calpain/calpastatin system in cystic fibrosis 130
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 129
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 129
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 128
A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation 126
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 125
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 124
Acyl-CoA-binding protein is a potent m-calpain activator 121
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 116
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 116
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 116
Cell protection from Ca2+-overloading by bioactive molecules extracted from olive pomace 115
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 114
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 113
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 113
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 112
Role of calpain-1 in the early phase of experimental ALS 111
“Susceptibility of NOS isoforms to calpain digestion is modulated by the expression levels of HSP90” 108
Role of the regulatory domain of calpastatin in the autoproteolytic activation of calpain 106
Changes in intracellular localization of calpastatin during calpain activation 105
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 102
Age-dependent degradation of calpastatin in kidney of hypertensive rats 100
Is the Expression of [-G93A(+)] human SOD1 a model to study neurodegenerations? 98
Phosphorylation of rat brain calpastatins by protein kinase C. 94
In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS-HSP90 heterocomplex 93
"Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease?" 92
Calpain-mediated activation of NO synthase in human neuroblastoma SK-N-BE cells 89
Modulation of rat brain calpastatin efficiency by post-translational modifications 85
Cytosolic levels of calpastatin are regulated by limited proteolysis 85
Regulation of the calpain-calpastatin system in rat brain during alteration of Ca2+ homeostasis 83
Differential degradation of calpastatin by mu- and m-calpain in Ca(2+)-enriched human neuroblastoma LAN-5 cells. 83
Properties of calpastatin forms in rat brain 82
"Cytosolic levels of calpastatin are regulated by limited proteolysis" 82
Activation of calpain 1 and protein kinase C alpha promotes a constitutive expression and release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 82
“Involvement of the Calpain/Calpastatin System in Familial Amyotrophic Lateral Sclerosis” 81
Adaptive modifications in the calpain/calpastatin system in brain cells after persistent alteration in Ca2+ homeostasis 81
A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation 78
“How is alteration in Ca2+ homeostasis controlled in brain? A role for calpastatin” 77
Production and purification of recombinant calpastatin 75
A Novel signalling mechanism promoting Ca(2+) driven cell responses through high-mobility group box-1/NMDA receptor interaction. 74
“Regulation of calpain activity in brain following altered Ca2+ homeostasis” 74
Isolation of endogenous calpastatin 71
Bioactive molecules isolated from olive pomace extract protect cells from calcium mediated damages 70
"Intracellular calpastatin proteolysis: a salvage mechanism or a prelude to cell damage?" 67
Principi di biochimica 67
Specific role of calpain-1 associated to N-methy l-D-aspartate receptor in lipid rafts microdomains 64
Association of calpastatin with inactive calpain: a novel mechanism to control the activation of the protease? 64
Interaction between catalitically inactive calpain and calpastatin: evidence for its occurrence in stimulated cells 62
Heteromerization of Dopamine D2 and Oxytocin Receptor in Adult Striatal Astrocytes 61
Biochemical and biophysical evidence for the A2A-D2 heteroreceptors in striatal astrocytes 61
Immunoblotting for calpastatin expression 60
Functional role of HSP90 complexes with endothelial nitric-oxide synthase (eNOS) and calpain on nitric oxide generation in endothelial cells 59
“Entry in the quiescent G0 cell state requires enhanced calpain activation” 57
Homozygous familial hypercholesterolemia in Italy: Clinical and molecular features 57
Biochimica 56
The calpain-calpastatin system in human central nervous system tumours: new insight on its prognostic value 54
Heterodimer of A2A and Oxytocin Receptors Regulating Glutamate Release in Adult Striatal Astrocytes 46
A2A-D2 heteromerization on striatal astrocytes: evidence and modulation of glutamate release 45
Reactive astrocytosis in a mouse model of chronic polyamine catabolism activation 42
Identification of potential leukocyte biomarkers related to drug recovery of cftr: Clinical applications in cystic fibrosis 41
Temperature-Dependent Olive Pomace Extraction for Obtaining Bioactive Compounds Preventing the Death of Murine Cortical Neurons 39
Long-term efficacy of lipoprotein apheresis and lomitapide in the treatment of homozygous familial hypercholesterolemia (HoFH): a cross-national retrospective survey 31
A2A and Oxytocin receptor heteromers: exploring their role as modulators of glutamate release in adult striatal astrocytes 27
Revisiting the role of leukocytes in cystic fibrosis 26
Reported muscle symptoms during statin treatment amongst Italian dyslipidaemic patients in the real-life setting: the PROSISA Study 23
The Involvement of Polyamines Catabolism in the Crosstalk between Neurons and Astrocytes in Neurodegeneration 21
Dysmetabolism of Polyamines in a Transgenic Mouse Model Overexpressing Spermine Oxidase in Cerebrocortical Neurons: Reactive Astrocytosis and Neuronal Suffering 21
Reactive Astrocytosis in a Mouse Model of Chronic Polyamine Catabolism Activation 18
Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization 16
Modulation of Plasmatic Matrix Metalloprotease 9: A Promising New Tool for Understanding the Variable Clinical Responses of Patients with Cystic Fibrosis to Cystic Fibrosis Transmembrane Conductance Regulator Modulators 16
The oxytocin receptor heteromers as regulators of glutamatergic transmission in striatal astrocytes 13
OTR-D2 heterodimerization in striatal astrocytes: biochemical and biophysical evidence 10
Expression of calpastatin hcast 3-25 and activity of the calpain/calpastatin system in human glioblastoma stem cells: possible involvement of hcast 3-25 in cell differentiation 6
Totale 7.546
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Categoria #
all - tutte 22.751
article - articoli 15.891
book - libri 457
conference - conferenze 5.836
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 567
Totale 45.502
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.862 0 0 107 141 190 205 272 142 169 315 248 73
2020/2021526 31 48 41 51 34 37 21 53 38 88 39 45
2021/2022951 30 55 82 71 39 58 63 219 48 98 41 147
2022/2023944 74 70 15 118 109 148 3 51 166 18 153 19
2023/2024702 33 65 17 94 66 148 30 26 40 24 51 108
2024/2025313 149 155 9 0 0 0 0 0 0 0 0 0
Totale 7.546