Fanconi anemia (FA) is a complex tumor-prone disease defined by an entangled genotype and phenotype. Despite enormous efforts in the last 20 years, a comprehensive and integrated view of the disease is still missing. The aim of this pilot study was to establish whether a global microRNA (miRNA) analysis approach could be helpful in defining aspects in FA phenotype, which might deserve future attention with the perspective to develop miRNA-based therapies.

A Global MicroRNA Profile in Fanconi Anemia: A Pilot Study

Degan, Paolo;Longobardi, MariaGrazia;Pulliero, Alessandra;Cuccarolo, Paola;Dufour, Carlo;Ravera, Silvia;Calzia, Daniela;Izzotti, Alberto
2019-01-01

Abstract

Fanconi anemia (FA) is a complex tumor-prone disease defined by an entangled genotype and phenotype. Despite enormous efforts in the last 20 years, a comprehensive and integrated view of the disease is still missing. The aim of this pilot study was to establish whether a global microRNA (miRNA) analysis approach could be helpful in defining aspects in FA phenotype, which might deserve future attention with the perspective to develop miRNA-based therapies.
File in questo prodotto:
File Dimensione Formato  
Metabolic Syndrome and Related Disorders_2019.pdf

accesso chiuso

Tipologia: Documento in versione editoriale
Dimensione 271.8 kB
Formato Adobe PDF
271.8 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11567/931281
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
social impact