Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. Update 2016

Antinori, Andrea; Di Biagio, Antonio; Marcotullio, Simone; Andreoni, Massimo; Chirianni, Antonio; d'Arminio Monforte, Antonella; Galli, Massimo; Mazzotta, Francesco; Mussini, Cristina; Puoti, Massimo; Lazzarin,; Adriano Andreoni, M; Chirianni, A; Antinori, A; Galli, M; Lazzarin, A; d'Arminio Monforte, A; Di Perri, G; Perno, Cf; Puoti, M; Vella, S; Marcotullio, S; Ammassari, A; Angarano, G; Antinori, A; Armignacco, O; Babudieri, S; Bini, T; Bonfanti, P; Bonora, S; Borderi, M; Breveglieri, M; Calza, L; Capobianchi, Mr; Cagarelli, R; Calcagno, A; Castagna, A; Castelli, F; Cattelan, Am; Cauda, R; Cingolani, A; Cinque, P; Corbelli, Gm; d'Arminio Monforte, A; D'Ettorre, G; De Carli, G; De Luca, A; Di Perri, G; Di Pietro, M; El Hamad, I; Errico, M; Gaeta, Gb; Galli, M; Gargiulo, M; Gervasoni, C; Giacomet, V; Giannini, A; Gianotti, N; Giaquinto, C; Girardi, E; Gori, A; Grossi, P; Guaraldi, G; Lichtner, M; Liuzzi, G; Lo Caputo, S; Maggi, P; Maggiolo, F; Marchetti, G; Marcotullio, S; Maserati, R; Mastroianni, C; Matteelli, A; Mazzotta, F; Menichetti, F; Mussini, C; Nozza, S; Oldrini, M; Parruti, G; Pascucci, Mg; Parrella, R; Perno, Cf; Prestileo, T; Puoti, M; Puro, V; Rancilio, L; Marina, R; Rezza, G; Rizzardini, G; Rusconi, S; Santoro, M; Sighinolfi, L; Stagnitta, M; Starnini, G; Tamburrini, E; Tambussi, G; Tavio, M; Torti, C; Vaccher, E; Viscoli, C; Visintini, R; Vullo, V; Zaccarelli, M; Zuccotti, Gv.

The Italian Society of Infectious and Tropical Diseases (SIMIT) of the Technical Health Committee, Ministry of Health (Sections L and M) of Italy have supported recommendations for the Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. This publication summarizes the latest updates to the 2016 version of the Italian Guidelines for the management of HIV-1 infected patients and the use of antiretroviral drugs. In particular, new recommendations were released concerning the following topics: estimate of the HIV continuum of care in Italy, optimal timing and preferred drug combinations for starting antiretroviral therapy, treatment optimization, and pre-exposure prophilaxis (PrEP). For a complete review of clinical and therapeutic relevant topics we refer the reader to the extended version of the Guidelines.