The clinical features of 10 cases of primary neuroendocrine carcinoma of the skin (Merker cell tumor) are reported. This cancer arises in the dermis and subcutaneous tissues of elderly individuals. Natural history is characterized by local recurrences (30\%), regional lymph node metastases (65\%) and distant metastases (40\%). Surgery is elective treatment, chemotherapy and radiotherapy resulted only to short-term palliative response.
Merkel cell carcinoma of the skin. Treatment of primary, recurrent and metastatic disease: review of clinical cases.
E. Raposio;SERTOLI, MARIO ROBERTO;SANTI, PIERLUIGI;CAFIERO, FERDINANDO
1997-01-01
Abstract
The clinical features of 10 cases of primary neuroendocrine carcinoma of the skin (Merker cell tumor) are reported. This cancer arises in the dermis and subcutaneous tissues of elderly individuals. Natural history is characterized by local recurrences (30\%), regional lymph node metastases (65\%) and distant metastases (40\%). Surgery is elective treatment, chemotherapy and radiotherapy resulted only to short-term palliative response.
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