The title compds. I (NRR1 = NEt2, NMe2, pyrrolidino, NHEt, NAcEt; R2 = H, Cl, NO2) and II [X = HOCH(CH2)2, (CH2)3, (CH2)5] were prepd. from I (R2 = H). I and II have antiallergic activity, I (R = R2 = H, R1 = Et) giving 92% protection at 500 mg/kg orally in the passive cutaneous anaphylaxis test.
[Chemistry and pharmacology of pyran derivatives. 16. Derivatives of 2-(dialkylamino)-7-methoxychromone with antiallergic activity].
MAZZEI, MAURO;BALBI, ALESSANDRO;
1985-01-01
Abstract
The title compds. I (NRR1 = NEt2, NMe2, pyrrolidino, NHEt, NAcEt; R2 = H, Cl, NO2) and II [X = HOCH(CH2)2, (CH2)3, (CH2)5] were prepd. from I (R2 = H). I and II have antiallergic activity, I (R = R2 = H, R1 = Et) giving 92% protection at 500 mg/kg orally in the passive cutaneous anaphylaxis test.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
