This work is focused on the hit optimization of previously identified dual Src/Abl inhibitors based on 1,3,4-thiadiazole and thiazole scaffolds.
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: from docking false positives to ATP-noncompetitive inhibitors.
SCHENONE, SILVIA;
2010-01-01
Abstract
This work is focused on the hit optimization of previously identified dual Src/Abl inhibitors based on 1,3,4-thiadiazole and thiazole scaffolds.File in questo prodotto:
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