A novel series of O-[2-hydroxy-3-(dialkylamino)propyl]ethers of (+)-camphor oxime was prepd. and tested for its cardiovascular, analgesic and anti-inflammatory properties. No significant anti-inflammatory and hypotensive activities were displayed by any of the compds., whereas several of them are reasonably active as antiarrhythmic and analgesic agents.
O-[2-Hydroxy-3-(dialkylamino)propyl]ethers of (+)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime (camphor oxime) with analgesic and antiarrhythmic activities
SCHENONE, SILVIA;BRUNO, OLGA;RANISE, ANGELO;BONDAVALLI, FRANCESCO;
2000-01-01
Abstract
A novel series of O-[2-hydroxy-3-(dialkylamino)propyl]ethers of (+)-camphor oxime was prepd. and tested for its cardiovascular, analgesic and anti-inflammatory properties. No significant anti-inflammatory and hypotensive activities were displayed by any of the compds., whereas several of them are reasonably active as antiarrhythmic and analgesic agents.
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