Red wine is a widely consumed beverage with multiple beneficial effects on human health. In the present paper, the anticaries properties of red wine were studied in vitro and ex vivo. Our in vitro findings shows that dealcoholised red wine, besides exerting antibacterial activity. strongly interferes with Streptococcus mutans adhesion to saliva-coated hydroxyapatite (sHA) beads. promotes its detachment from sHA, and powerfully inhibits in vitro biofilm formation. The main components responsible for such activities were found to be proanthocyanidins. The ability of red wine to inhibit ex vivo S. mutans biofilm formation on the occlusal surface of natural human teeth also was demonstrated.
Isolation of red wine components with anti-adhesion and anti-biofilm activity against Streptococcus mutans
STAUDER, MONICA NELLY;PRUZZO, CARLA;
2010-01-01
Abstract
Red wine is a widely consumed beverage with multiple beneficial effects on human health. In the present paper, the anticaries properties of red wine were studied in vitro and ex vivo. Our in vitro findings shows that dealcoholised red wine, besides exerting antibacterial activity. strongly interferes with Streptococcus mutans adhesion to saliva-coated hydroxyapatite (sHA) beads. promotes its detachment from sHA, and powerfully inhibits in vitro biofilm formation. The main components responsible for such activities were found to be proanthocyanidins. The ability of red wine to inhibit ex vivo S. mutans biofilm formation on the occlusal surface of natural human teeth also was demonstrated.
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