Influenza is a seasonal disease which affects millions of people every year and has a significant economic impact. Vaccines are the best strategy to fight this viral pathology, but they are not always available or administrable, prompting the search for antiviral drugs. RNA-dependent RNA polymerase (RdRp) recently emerged as a promising target, because of its key role in viral replication and its high conservation among viral strains.
Insights into RNA-dependent RNA Polymerase Inhibitors as Anti-influenza Virus Agents
Giacchello, Ilaria;Musumeci, Francesca;Greco, Chiara;Grossi, Giancarlo;Schenone, Silvia
2021-01-01
Abstract
Influenza is a seasonal disease which affects millions of people every year and has a significant economic impact. Vaccines are the best strategy to fight this viral pathology, but they are not always available or administrable, prompting the search for antiviral drugs. RNA-dependent RNA polymerase (RdRp) recently emerged as a promising target, because of its key role in viral replication and its high conservation among viral strains.
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