MUSUMECI, FRANCESCA MICHELA
MUSUMECI, FRANCESCA MICHELA
100006 - Dipartimento di Farmacia
A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant
2016-01-01 Radi, Marco; Schneider, Ralf; Fallacara, Anna Lucia; Botta, Lorenzo; Crespan, Emmanuele; Tintori, Cristina; Maga, Giovanni; Kissova, Miroslava; Calgani, Alessia; Richters, André; Musumeci, Francesca; Rauh, Daniel; Schenone, Silvia
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.
2013-01-01 Mori, M; Tintori, C; Christopher, Rs; Radi, M; Schenone, Silvia; Musumeci, Francesca; Brullo, Chiara; Sanità, P; Delle Monache, S; Angelucci, A; Kissova, M; Crespan, E; Maga, G; Botta, M.
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation.
2012-01-01 Radi, M; Evensen, L; Dreassi, E; Zamperini, C; Caporicci, M; Falchi, F; Musumeci, Francesca; Schenone, Silvia; Lorens, Jb; Botta, M.
A1 receptors ligands: past, present and future trends.
2010-01-01 Schenone, Silvia; Brullo, Chiara; Musumeci, Francesca; Bruno, Olga; Botta, M.
An update on dual Src/Abl inhibitors
2012-01-01 Musumeci, Francesca; Schenone, Silvia; Brullo, Chiara; Botta, M.
An Update on JAK Inhibitors
2019-01-01 Musumeci, Francesca; Greco, Chiara; Giacchello, Ilaria; Fallacara, Anna Lucia; Ibrahim, Munjed M; Grossi, Giancarlo; Brullo, Chiara; Schenone, Silvia
Analogs, formulations and derivatives of imatinib: A patent review
2015-01-01 Musumeci, Francesca; Schenone, Silvia; Grossi, Giancarlo; Brullo, Chiara; Sanna, Monica
Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells
2022-01-01 Monteleone, Lorenzo; Marengo, Barbara; Musumeci, Francesca; Grossi, Giancarlo; Carbone, Anna; Valenti, Giulia E.; Domenicotti, Cinzia; Schenone, Silvia
Applying molecular hybridization to design a new class of pyrazolo[3,4-d] pyrimidines as Src inhibitors active in hepatocellular carcinoma
2024-01-01 Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia
ATP-competitive inhibitors of mTOR: an update.
2011-01-01 Schenone, Silvia; Brullo, Chiara; Musumeci, Francesca; Radi, M; Botta, M.
Bcr-Abl tyrosine kinase inhibitors: A patent review
2015-01-01 Desogus, Andrea; Schenone, Silvia; Brullo, Chiara; Tintori, Cristina; Musumeci, Francesca
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
2023-01-01 Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Michela MUSUMECI, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena
Biologically driven synthesis of pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors: an old scaffold as a new tool for medicinal chemistry and chemical biology studies
2014-01-01 Schenone, Silvia; Radi, M; Musumeci, Francesca; Brullo, Chiara; Botta, M.
Click Chemistry, A Potent Tool in Medicinal Sciences
2015-01-01 Musumeci, Francesca; Schenone, Silvia; Desogus, Andrea; Nieddu, E.; Deodato, D.; Botta, L.
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma.
2015-01-01 Tintori, C; Fallacara, Al; Radi, M; Zamperini, C; Dreassi, E; Crespan, E; Maga, G; Schenone, Silvia; Musumeci, Francesca; Brullo, Chiara; Richters, A; Gasparrini, F; Angelucci, A; Festuccia, C; Delle Monache, S; Rauh, D; Botta, M.
CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction.
2014-01-01 Zamperini, C; Dreassi, E; Vignaroli, G; Radi, M; Dragoni, S; Schenone, Silvia; Musumeci, Francesca; Valoti, M; Antiochia, R; Botta, M.
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.
2013-01-01 Radi, M; Tintori, C; Musumeci, Francesca; Brullo, Chiara; Zamperini, C; Dreassi, E; Fallacara, Al; Vignaroli, G; Crespan, E; Zanoli, S; Laurenzana, I; Filippi, I; Maga, G; Schenone, Silvia; Angelucci, A; Botta, M.
Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.
2011-01-01 Radi, M; Dreassi, E; Brullo, Chiara; Crespan, E; Tintori, C; Bernardo, V; Valoti, M; Zamperini, C; Daigl, H; Musumeci, Francesca; Carraro, F; Naldini, A; Filippi, I; Maga, G; Schenone, Silvia; Botta, M.
Development of Pyrazolo[3,4- d]pyrimidine Kinase Inhibitors as Potential Clinical Candidates for Glioblastoma Multiforme
2020-01-01 Greco, C.; Taresco, V.; Pearce, A. K.; Vasey, C. E.; Smith, S.; Rahman, R.; Alexander, C.; Cavanagh, R. J.; Musumeci, F.; Schenone, S.
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling
2024-01-01 Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant | 1-gen-2016 | Radi, Marco; Schneider, Ralf; Fallacara, Anna Lucia; Botta, Lorenzo; Crespan, Emmanuele; Tintori, Cristina; Maga, Giovanni; Kissova, Miroslava; Calgani, Alessia; Richters, André; Musumeci, Francesca; Rauh, Daniel; Schenone, Silvia | |
| A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors. | 1-gen-2013 | Mori, M; Tintori, C; Christopher, Rs; Radi, M; Schenone, Silvia; Musumeci, Francesca; Brullo, Chiara; Sanità, P; Delle Monache, S; Angelucci, A; Kissova, M; Crespan, E; Maga, G; Botta, M. | |
| A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation. | 1-gen-2012 | Radi, M; Evensen, L; Dreassi, E; Zamperini, C; Caporicci, M; Falchi, F; Musumeci, Francesca; Schenone, Silvia; Lorens, Jb; Botta, M. | |
| A1 receptors ligands: past, present and future trends. | 1-gen-2010 | Schenone, Silvia; Brullo, Chiara; Musumeci, Francesca; Bruno, Olga; Botta, M. | |
| An update on dual Src/Abl inhibitors | 1-gen-2012 | Musumeci, Francesca; Schenone, Silvia; Brullo, Chiara; Botta, M. | |
| An Update on JAK Inhibitors | 1-gen-2019 | Musumeci, Francesca; Greco, Chiara; Giacchello, Ilaria; Fallacara, Anna Lucia; Ibrahim, Munjed M; Grossi, Giancarlo; Brullo, Chiara; Schenone, Silvia | |
| Analogs, formulations and derivatives of imatinib: A patent review | 1-gen-2015 | Musumeci, Francesca; Schenone, Silvia; Grossi, Giancarlo; Brullo, Chiara; Sanna, Monica | |
| Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells | 1-gen-2022 | Monteleone, Lorenzo; Marengo, Barbara; Musumeci, Francesca; Grossi, Giancarlo; Carbone, Anna; Valenti, Giulia E.; Domenicotti, Cinzia; Schenone, Silvia | |
| Applying molecular hybridization to design a new class of pyrazolo[3,4-d] pyrimidines as Src inhibitors active in hepatocellular carcinoma | 1-gen-2024 | Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia | |
| ATP-competitive inhibitors of mTOR: an update. | 1-gen-2011 | Schenone, Silvia; Brullo, Chiara; Musumeci, Francesca; Radi, M; Botta, M. | |
| Bcr-Abl tyrosine kinase inhibitors: A patent review | 1-gen-2015 | Desogus, Andrea; Schenone, Silvia; Brullo, Chiara; Tintori, Cristina; Musumeci, Francesca | |
| Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme | 1-gen-2023 | Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Michela MUSUMECI, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena | |
| Biologically driven synthesis of pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors: an old scaffold as a new tool for medicinal chemistry and chemical biology studies | 1-gen-2014 | Schenone, Silvia; Radi, M; Musumeci, Francesca; Brullo, Chiara; Botta, M. | |
| Click Chemistry, A Potent Tool in Medicinal Sciences | 1-gen-2015 | Musumeci, Francesca; Schenone, Silvia; Desogus, Andrea; Nieddu, E.; Deodato, D.; Botta, L. | |
| Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma. | 1-gen-2015 | Tintori, C; Fallacara, Al; Radi, M; Zamperini, C; Dreassi, E; Crespan, E; Maga, G; Schenone, Silvia; Musumeci, Francesca; Brullo, Chiara; Richters, A; Gasparrini, F; Angelucci, A; Festuccia, C; Delle Monache, S; Rauh, D; Botta, M. | |
| CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction. | 1-gen-2014 | Zamperini, C; Dreassi, E; Vignaroli, G; Radi, M; Dragoni, S; Schenone, Silvia; Musumeci, Francesca; Valoti, M; Antiochia, R; Botta, M. | |
| Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant. | 1-gen-2013 | Radi, M; Tintori, C; Musumeci, Francesca; Brullo, Chiara; Zamperini, C; Dreassi, E; Fallacara, Al; Vignaroli, G; Crespan, E; Zanoli, S; Laurenzana, I; Filippi, I; Maga, G; Schenone, Silvia; Angelucci, A; Botta, M. | |
| Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study. | 1-gen-2011 | Radi, M; Dreassi, E; Brullo, Chiara; Crespan, E; Tintori, C; Bernardo, V; Valoti, M; Zamperini, C; Daigl, H; Musumeci, Francesca; Carraro, F; Naldini, A; Filippi, I; Maga, G; Schenone, Silvia; Botta, M. | |
| Development of Pyrazolo[3,4- d]pyrimidine Kinase Inhibitors as Potential Clinical Candidates for Glioblastoma Multiforme | 1-gen-2020 | Greco, C.; Taresco, V.; Pearce, A. K.; Vasey, C. E.; Smith, S.; Rahman, R.; Alexander, C.; Cavanagh, R. J.; Musumeci, F.; Schenone, S. | |
| Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling | 1-gen-2024 | Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S. |