MUSUMECI, FRANCESCA MICHELA
MUSUMECI, FRANCESCA MICHELA
100006 - Dipartimento di Farmacia
3-Cyano-4,6-diphenyl-pyridine amino acid derivatives active as influenza A polymerase inhibitors
2018-01-01 Giacchello, I.; Trist, I. M. L; Musumeci, F.; Greco, C.; D’Agostino, I.; Deodato, D.; Loregian, A.; Grossi, G.; Schenone, S.
6-Substituted pyrazolo[3,4-d]pyrimidines: new promising compounds in the fight against Neuroblastoma
2014-01-01 Musumeci, F.; Desogus, A.; Schenone, S.; Brullo, C.; Fallacara, A. L.; Tintori, C.; Dreassi, E.; Zamperini, C.; Maga, G.; Angelucci, A.; Botta,
A family of nitrogen-containing heterocycles as sirtuin inhibitors: synthesis and invitro biological evaluation
2024-01-01 Falesiedi, M.; Scarano, N.; Grossi, G.; Carbone, A.; Brullo, C.; Musumeci, Francesca; Bruzzone, S.; Cichero, E.; Schenone, S.
Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors
2024-01-01 Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia.
Design and synthesis of a new series of pyrazolo[3,4- d]pyrimidines active as SGK1 inhibitors in ovarian cancer cell models
2022-01-01 Musumeci, F.; D’Antona, L.; Carbone, A.; Ortuso, F.; Alcaro, S.; Perrotti, N.; Schenone, S.
Design, synthesis, and biological evaluation of a new series of pyrazolo[3,4-d]pyrimidines active as SGK1 inhibitors. A lead optimization study.
2021-01-01 Musumeci, F.; D’Antona, L.; Carbone, A.; Ortuso, F.; Alcaro, S.; Perrotti, N.; Schenone, S.
Development of a new potential theranostic prodrug for targeting glioblastoma multiforme
2022-01-01 Carbone, A.; D’Agostino, I.; Cianciusi, A.; Musumeci, F.; Salis, A.; D’Antona, L.; Petroni, D.; Dreassi, E.; Menichetti, L.; Schenone, S.
Exploring SAR of a new generation of pyrazolo[3,4-d]pyrimidines as Fyn tyrosine kinase inhibitors
2018-01-01 Musumeci, F.; Greco, Chiara; Navarro Pinin, L.; Giacchello, Ilaria; Crespan, E.; Passannanti, R.; Trist, I. M. L.; Maga, G.; Schenone, S.; Botta, M.
Formulated pyrazolo[3,4-d]pyrimidines active on GBM cell lines
2019-01-01 Greco, C.; Cavanagh, R.; Taresco, V.; Petromilo, H.; Musumeci, F.; Rahman, R.; Alexander, C.; Schenone, S.
Formulation Of Pyrazolo[3,4-d]pyrimidines Kinase Inhibitors For The Treatment Of Glioblastoma Multiforme
2019-01-01 Greco, Chiara; Cavanagh, Robert; Taresco, Vincenzo; Vasey, Catherine; Musumeci, Francesca; Rahman, Ruman; Alexander, Cameron; Schenone, Silvia
Identification of a new family of pyrimidine and pyridine derivatives as disruptors of the viral RNA-dependent RNA polymerase
2019-01-01 Petromilo, H.; Giacchello, I.; Musumeci, F.; Greco, C.; D’Agostino, I.; Loregian, A.; Schenone, S.; Botta, M.
In silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists
2024-01-01 Scarano, Naomi; Di Palma, Francesco; Spinelli, Sonia; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena
IN SILICO INVESTIGATION OF LANCL-2 ACTIVATION MECHANISM: THE CASE OF BT-11 (OMILANCOR).
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena
Insight into Fyn and SGK1 kinases as new targets in medicinal chemistry: design and synthesis of pyrazolo[3,4-d]pyrimidine libraries
2017-01-01 Musumeci, F.; Schenone, S.; Fallacara, A. L.; Trist, I.; Perrotti, N.; Alcaro, S.; Ortuso, F.; Maga, G.
New potential anti-flu agents acting by disrupting the PA-PB1 interaction of viral polymerase.
2021-01-01 Cianciusi, A.; Musumeci, F.; D’Agostino, I.; Schenone, S.
One-pot synthesis of indolyl- pyrrolones as Pim1 inhibitors
2011-01-01 Musumeci, Francesca; Schenone, Silvia; Brullo, Chiara; M., Radi; M., Botta
Pyrazolo[3,4-d]pyrimidine active on neuroblastoma cells
2018-01-01 Greco, C.; Musumeci, F.; Giacchello, I.; Gorjòn de Pablo, G.; Molinari, A.; Fallacara, A. L.; Di Maria, S.; Marengo, B.; Domenicotti, C.; Botta, M.; Schenone, S.
PYRAZOLO[3,4-d]PYRIMIDINE DERIVATIVES AS SIRTUIN INHIBITORS: DESIGN, SYNTHESIS AND PRELIMINARY in vitro EVALUATION
2024-01-01 Falesiedi, Marta; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia
Pyrazolo[3,4-d]pyrimidines as tyrosine kinase inhibitors: synthesis and biological evaluation
2018-01-01 Musumeci, F.; Greco, C.; Giacchello, I.; Crespan, E.; Maga, G.; Schenone, S.; Fallacara, A. L.; Molinari, A.; Botta, M.
SGK1 as a new target for anticancer agents: a hit-to-lead study
2017-01-01 Musumeci, F.; Greco, C.; Alcaro, S.; Ortuso, F.; Perrotti, N.; Schenone, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3-Cyano-4,6-diphenyl-pyridine amino acid derivatives active as influenza A polymerase inhibitors | 1-gen-2018 | Giacchello, I.; Trist, I. M. L; Musumeci, F.; Greco, C.; D’Agostino, I.; Deodato, D.; Loregian, A.; Grossi, G.; Schenone, S. | |
| 6-Substituted pyrazolo[3,4-d]pyrimidines: new promising compounds in the fight against Neuroblastoma | 1-gen-2014 | Musumeci, F.; Desogus, A.; Schenone, S.; Brullo, C.; Fallacara, A. L.; Tintori, C.; Dreassi, E.; Zamperini, C.; Maga, G.; Angelucci, A.; Botta, | |
| A family of nitrogen-containing heterocycles as sirtuin inhibitors: synthesis and invitro biological evaluation | 1-gen-2024 | Falesiedi, M.; Scarano, N.; Grossi, G.; Carbone, A.; Brullo, C.; Musumeci, Francesca; Bruzzone, S.; Cichero, E.; Schenone, S. | |
| Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors | 1-gen-2024 | Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia. | |
| Design and synthesis of a new series of pyrazolo[3,4- d]pyrimidines active as SGK1 inhibitors in ovarian cancer cell models | 1-gen-2022 | Musumeci, F.; D’Antona, L.; Carbone, A.; Ortuso, F.; Alcaro, S.; Perrotti, N.; Schenone, S. | |
| Design, synthesis, and biological evaluation of a new series of pyrazolo[3,4-d]pyrimidines active as SGK1 inhibitors. A lead optimization study. | 1-gen-2021 | Musumeci, F.; D’Antona, L.; Carbone, A.; Ortuso, F.; Alcaro, S.; Perrotti, N.; Schenone, S. | |
| Development of a new potential theranostic prodrug for targeting glioblastoma multiforme | 1-gen-2022 | Carbone, A.; D’Agostino, I.; Cianciusi, A.; Musumeci, F.; Salis, A.; D’Antona, L.; Petroni, D.; Dreassi, E.; Menichetti, L.; Schenone, S. | |
| Exploring SAR of a new generation of pyrazolo[3,4-d]pyrimidines as Fyn tyrosine kinase inhibitors | 1-gen-2018 | Musumeci, F.; Greco, Chiara; Navarro Pinin, L.; Giacchello, Ilaria; Crespan, E.; Passannanti, R.; Trist, I. M. L.; Maga, G.; Schenone, S.; Botta, M. | |
| Formulated pyrazolo[3,4-d]pyrimidines active on GBM cell lines | 1-gen-2019 | Greco, C.; Cavanagh, R.; Taresco, V.; Petromilo, H.; Musumeci, F.; Rahman, R.; Alexander, C.; Schenone, S. | |
| Formulation Of Pyrazolo[3,4-d]pyrimidines Kinase Inhibitors For The Treatment Of Glioblastoma Multiforme | 1-gen-2019 | Greco, Chiara; Cavanagh, Robert; Taresco, Vincenzo; Vasey, Catherine; Musumeci, Francesca; Rahman, Ruman; Alexander, Cameron; Schenone, Silvia | |
| Identification of a new family of pyrimidine and pyridine derivatives as disruptors of the viral RNA-dependent RNA polymerase | 1-gen-2019 | Petromilo, H.; Giacchello, I.; Musumeci, F.; Greco, C.; D’Agostino, I.; Loregian, A.; Schenone, S.; Botta, M. | |
| In silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists | 1-gen-2024 | Scarano, Naomi; Di Palma, Francesco; Spinelli, Sonia; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena | |
| IN SILICO INVESTIGATION OF LANCL-2 ACTIVATION MECHANISM: THE CASE OF BT-11 (OMILANCOR). | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena | |
| Insight into Fyn and SGK1 kinases as new targets in medicinal chemistry: design and synthesis of pyrazolo[3,4-d]pyrimidine libraries | 1-gen-2017 | Musumeci, F.; Schenone, S.; Fallacara, A. L.; Trist, I.; Perrotti, N.; Alcaro, S.; Ortuso, F.; Maga, G. | |
| New potential anti-flu agents acting by disrupting the PA-PB1 interaction of viral polymerase. | 1-gen-2021 | Cianciusi, A.; Musumeci, F.; D’Agostino, I.; Schenone, S. | |
| One-pot synthesis of indolyl- pyrrolones as Pim1 inhibitors | 1-gen-2011 | Musumeci, Francesca; Schenone, Silvia; Brullo, Chiara; M., Radi; M., Botta | |
| Pyrazolo[3,4-d]pyrimidine active on neuroblastoma cells | 1-gen-2018 | Greco, C.; Musumeci, F.; Giacchello, I.; Gorjòn de Pablo, G.; Molinari, A.; Fallacara, A. L.; Di Maria, S.; Marengo, B.; Domenicotti, C.; Botta, M.; Schenone, S. | |
| PYRAZOLO[3,4-d]PYRIMIDINE DERIVATIVES AS SIRTUIN INHIBITORS: DESIGN, SYNTHESIS AND PRELIMINARY in vitro EVALUATION | 1-gen-2024 | Falesiedi, Marta; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia | |
| Pyrazolo[3,4-d]pyrimidines as tyrosine kinase inhibitors: synthesis and biological evaluation | 1-gen-2018 | Musumeci, F.; Greco, C.; Giacchello, I.; Crespan, E.; Maga, G.; Schenone, S.; Fallacara, A. L.; Molinari, A.; Botta, M. | |
| SGK1 as a new target for anticancer agents: a hit-to-lead study | 1-gen-2017 | Musumeci, F.; Greco, C.; Alcaro, S.; Ortuso, F.; Perrotti, N.; Schenone, S. |