IRIS
RICCIARELLI, ROBERTA
 Distribuzione geografica
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Continente #
EU - Europa 11.586
Totale 11.586
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Nazione #
IT - Italia 11.586
Totale 11.586
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Città #
Genova 8.974
Rapallo 1.314
Genoa 1.018
Vado Ligure 265
Bordighera 15
Totale 11.586
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Nome #
Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma 187
PKCδ Sensitizes Neuroblastoma Cells to L-Buthionine-Sulfoximine and Etoposide Inducing Reactive Oxygen Species Overproduction and DNA Damage 160
Phosphodiesterase-4D: an enzyme to remember 158
Presynaptic GLP-1 receptors enhance the depolarization-evoked release of Glutamate and GABA in the mouse cortex and hippocampus 155
Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease. 153
Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors 148
New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment 145
Cholesterol and amyloid-beta: evidence for a cross-talk between astrocytes and neuronal cells 144
Vitamin E reduces the uptake of oxidized LDL by inhibiting CD36 scavenger receptor expression in cultured aortic smooth muscle cells 143
DNA oxidative damage of neoplastic rat liver lesions 140
Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism 139
Amyloid β: Walking on the dark side of the moon 138
The amyloid cascade hypothesis in Alzheimer’s disease: it’s time to change our mind 136
Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene. 133
3-Aminobenzamide inhibition of protein kinase C at a cellular level. 132
A novel PDE4D inhibitor increases amyloid-beta deposition in neuronal cultured cells and improves memory in rats 132
A physiological role for amyloid beta in the cyclic AMP-stimulated long term potentiation. 131
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. 128
The p38MAPK inhibition: A new combined approach to reduce neuroblastoma survival under etoposide treatment 127
GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses. 127
Protein kinase C: An attractive target for cancer therapy 126
Alpha-tocopherol as a modulator of smooth muscle cell proliferation. 124
Synthesis, Biological Evaluation, and Molecular Modeling of New 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-Dimethylmorpholino)-2-oxoethyl) Oxime (GEBR-7b) Related Phosphodiesterase 4D (PDE4D) Inhibitors. 124
Amyloid Beta and the Brain: Where Are We Now? 124
Modulation of proteasome activity by vitamin E in THP-1 monocytes. 123
Characterization of three human sec14p-like proteins: alpha-Tocopherol transport activity and expression pattern in tissues. 123
Scavenger receptor regulation and atherosclerosis. 122
Vitamin E inhibits CD36 scavenger receptor expression in hypercholesterolemic rabbits 122
Vitamin E: protective role of a Janus Molecule 121
Evidence against the overexpression of APP in Down Syndrome 121
A novel mechanism for cyclic adenosine monophosphate-mediated memory formation: role of amyloid beta 117
PDE4D inhibitors: a potential strategy for the treatment of memory impairment? 117
Vitamin E mediated response of smooth muscle cell to oxidant stress. 116
Novel 5' exon of scavenger receptor CD36 is expressed in cultured human vascular smooth muscle cells and atherosclerotic plaques 115
Cyclic adenosine monophosphate as an endogenous modulator of the amyloid-β precursor protein metabolism 115
Glucagon-Like Peptide 1, Neuroprotection and Neurodegenerative Disorders 115
Cholesterol and Alzheimer’s disease: a still poorly understood correlation 114
Amyloid-beta peptide is needed for cGMP-induced long-term potentiation and memory 113
Isoelectric point mobility shift assay for rapid screening of charged and uncharged ligands bound to proteins. 111
New compounds having a selective PDE4D inhibiting activity 111
Vitamins and regulation of gene expression 109
Oxidative stress and protein kinase C activity modulation 109
A physiological role for amyloid beta in the cyclic AMP-stimulated long term potentiation. 109
Role of glutathione in cancer progression and chemoresistance 108
Cholesterol and Amyloid-β: Evidence for a Cross-Talk between Astrocytes and Neuronal Cells. 106
Vitamin E 80th anniversary: a double life, not only fighting radicals. 105
Scavenger receptors and modified lipoproteins: fatal attractions? 100
Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages 100
Vitamin E and neurodegenerative diseases. 99
Microarray analysis in Alzheimer’s disease and normal aging 99
Amyloid Precursor Protein Processing: Role of Peroxisome Proliferator-Activated Receptor-Gamma. 99
N-Alkyl Carbazole Derivatives as New Tools for Alzheimer’s Disease: Preliminary Studies 99
cAMP, cGMP and Amyloid Beta: three ideal partners for memory formation 98
p38MAPK inhibition: a new combined approach to reduce neuroblastoma resistance under etoposide treatment 98
Modulation of cAMP levels by high-fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression. 97
Investigating the amyloid-beta enhancing effect of cGMP in neuro2a cells 96
Role of peroxisome proliferator-activated receptor gamma in amyloid precursor protein processing and amyloid beta-mediated cell death 96
Cloning of novel human SEC14p-like proteins: ligand binding and functional properties. 96
Molecular basis of alpha-tocopherol control of smooth muscle cell proliferation. 94
Regulation and deregulation of vascular smooth muscle cells by reactive oxygen species and by alpha-tocopherol 93
Involvement of myosin II-B and protein kinase C in the processing of APP 93
p38MAPK inhibition: a new combined approach to reduce neuroblastoma resistance under etoposide treatment. 93
Neutrophil chemotaxis inhibitors: new tools against cancer metastasis? 91
alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state. 90
Molecular events of the inflammation process that are affected by alpha-tocopherol. Antioxidant and gene expression in the process of inflammation and wound repair. 89
Involvement of Myosin II-B and Protein Kinase C in the Processing of the Alzheimer Amyloid Precursor Protein 89
cAMP-induced Aβ production and its role in the expression of LTP. 88
Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D 88
Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages 87
Cell signaling: Regulation by tocopherols 86
Stimulation of the amyloid-β precursor protein metabolism by cAMP 86
Inhibition of p38MAPK: A Combined Strategy for Sensitizing Neuroblastoma Cells to Etoposide Through the Modulation of Pro-Inflammation Markers. 86
CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol. 86
Age-dependent increase of collagenase expression can be reduced by alpha-tocopherol via protein kinase C inhibition. 85
Alpha-tocopherol induces expression of connective tissue growth factor and antagonizes tumor necrosis factor-alpha-mediated downregulation in human smooth muscle cells 85
CD36 over-expression in ritonavir treated THP-1 cells is reversed by alpha-tocopherol 84
Protein kinase C-dependent {alpha}-secretory processing of the amyloid precursor protein is mediated by phosphorylation of myosin II-B 84
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes 83
Gebr-7b, a novel selective PDE4D inhibitor, increases beta amyloid secretion in neuronal cultured cells and improves cognitive function in rodents 83
Processing of the amyloid precursor protein: role pf protein kinase C and myosin II B 81
A novel cAMP/PKA/APP/Abeta pathway modulates hippocampal LTP 80
Protein kinase C inactivation by Fenton’s-reaction at discrete Cu++ binding sites 80
The 80th anniversary of vitamin E: beyond its antioxidant properties. Biol Chem. 2002 Mar-Apr;383(3-4):457-65. 79
PKC delta: a limiting kinase in DNA oxidative damage and apoptosis of neuroblastoma cells 79
Expression and activity of PKC isoforms in ethanol-treated rat hepatocytes 76
Inflammation and beta-amyloid in normal aging and Alzheimer disease 75
Vitamin E in cell signaling 74
Modulation of proteasome activity by vitamin E in THP-1 monocytes 73
Molecular basis of alpha-tocopherol action and its protective role against diabetic complications 72
Role of PKC in sensitivity and resistance of neuroblastoma cells to etoposide 72
Stimulation of the amyloid beta precursor protein metabolism by cAMP 71
CD36 overexpression in human brain correlates with beta-amyloid deposition but not with Alzheimer's disease 70
Effects of vitamin E on extracellular matrix components of the vascular wall: Non-antioxidant roles in the prevention of cardiovascular diseases. 70
Nonantioxidant functions of alpha-tocopherol in smooth muscle cells. 69
Specific cellular responses to alpha-tocopherol. 69
Control of cell proliferation by alpha-tocopherol 68
GEBR-32A, A NEW PROMISING PDE4D INHIBITOR FOR TREATMENT OF ALZHEIMER'S DISEASE 67
Regulation of recombinant PKC alpha activity by protein phosphatase 1 and protein phosphatase 2A. 67
Cyclic AMP modulates the metabolism of the amyloid beta precursor protein 67
HIV protease inhibitors-induced atherosclerosis: prevention by alpha-tocopherol. 63
Totale 10.418
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Categoria #
all - tutte 33.935
article - articoli 29.213
book - libri 0
conference - conferenze 3.488
curatela - curatele 0
other - altro 0
patent - brevetti 208
selected - selezionate 0
volume - volumi 1.026
Totale 67.870
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.716 0 0 163 170 241 289 411 165 237 524 402 114
2020/2021845 28 88 86 64 54 50 53 85 67 130 70 70
2021/20221.481 52 126 114 140 64 89 92 362 48 141 81 172
2022/20231.558 139 92 54 144 240 289 17 128 280 11 139 25
2023/2024804 45 123 20 102 73 152 48 29 25 31 51 105
2024/2025280 58 187 35 0 0 0 0 0 0 0 0 0
Totale 11.869