IRIS
VILLA, VALENTINA
 Distribuzione geografica
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Continente #
EU - Europa 5.357
Totale 5.357
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Nazione #
IT - Italia 5.357
Totale 5.357
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Città #
Genova 3.952
Rapallo 554
Genoa 433
Vado Ligure 399
Bordighera 19
Totale 5.357
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Nome #
Amyloid precursor protein modulates ERK1/2 signaling 162
Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm 159
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death 157
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure 157
Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231 154
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells 154
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 152
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 151
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 149
Novel celecoxib analogues inhibit glial production of prostaglandinE2, nitric oxide, and oxygen radicals reverting the neuroinflammatoryresponses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide 132
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 130
Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants 128
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 127
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction 126
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons 126
p38 MAP Kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells 125
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells 125
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation 125
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment 124
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 123
Emerging targets in pituitary adenomas: role of the CXCL12/CXCR4-R7 system 121
Role of prion protein aggregation in neurotoxicity 119
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 119
High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein 119
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein 118
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation 113
The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development 109
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity 108
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization 102
Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity 100
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities” 99
Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide 97
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling 96
Aminoterminally truncated human Prion protein fragment 90-231 forms intracellular aggregates and causes lysosomal loss of impermeability 95
Molecular mechanisms involved in the aggregation and fibril formation of the recombinant human prion fragment PrP90-231 94
Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231 (hPrP90-231), as possible mechanism of its neurotoxic effects 92
Psychological treatments and psychotherapies in the neurorehabilitation of pain: Evidences and recommendations from the italian consensus conference on pain in neurorehabilitation 88
Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements 86
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE 81
Prion protein fragment 90-231 induces microglia activation: role of ERK1/2 and p38 MAP kinases in nitric oxide production and CCL5 secretion 79
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231 76
Somatostatinergic control of Kaposi’s sarcoma growth through the inhibition of angiogenesis 75
Expression of somatostatin receptors mRNA in human meningiomas and their implication in in vitro antiproliferative activity 69
Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform 67
Study of the Molecular Mechanism Responsible of the Conformational Changes Induced by E200K and D202N Pathological PrP Mutation 67
Molecular mechanisms mediating the neuroprotective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231) 67
Study of the molecular mechanisms responsible of the transition of the prion protein fragment 90-231 in a neurotoxic conformation. 61
Somatostatin receptor expression in patients with stromal tumors of the gastrointestinal tract 57
Somatostatin receptor expression in stromal tumors of the gastrointestinal 48
The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 44
Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro 21
Totale 5.473
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Categoria #
all - tutte 15.991
article - articoli 15.019
book - libri 0
conference - conferenze 763
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 209
Totale 31.982
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.125 0 0 0 0 129 157 208 97 110 216 165 43
2020/2021372 30 30 29 26 41 30 31 45 24 38 22 26
2021/2022672 16 75 35 68 20 52 61 149 20 54 32 90
2022/2023648 48 43 5 64 110 116 1 54 94 5 101 7
2023/2024346 22 33 7 48 22 87 28 20 17 6 24 32
2024/2025412 32 68 30 117 165 0 0 0 0 0 0 0
Totale 5.473