IRIS
SPARATORE, BIANCA
 Distribuzione geografica
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Continente #
EU - Europa 12.021
Totale 12.021
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Nazione #
IT - Italia 12.021
Totale 12.021
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Città #
Genova 10.039
Rapallo 1.248
Genoa 722
Bordighera 12
Totale 12.021
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 154
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 146
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 143
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 142
The calpain-calpastatin system in mammalian cells: properties and possible functions 140
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 134
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 130
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 128
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 126
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 125
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 124
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 122
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 122
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 122
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 121
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 120
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 120
A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation 119
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 118
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 117
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 117
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 117
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 117
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 116
Acyl-CoA-binding protein is a potent m-calpain activator 115
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 115
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NK p30 115
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 114
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 113
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 112
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 112
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 112
High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo. 111
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 111
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 110
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 110
Introduction of beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells 109
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 109
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 109
The breakpoint identified in a balanced de novo translocation t(7;9)(p14.1;q31.3) disrupts the A-kinase (PRKA) anchor protein 2 gene (AKAP2) on chromosome 9 in a patient with Kallmann syndrome and bone anomalies 108
Modulation of the intracellular Ca2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells 108
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 107
NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy? 107
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 106
Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation 106
Endogenous inhibitors of lysosomal proteinases 106
18β-Glycyrrhetic Acid Inhibits Immune Activation Triggered by HMGB1, a Pro-inflammatory Protein Found in the Tear Fluid during Conjunctivitis and Blepharitis. 106
Regulation of the Ca2+-dependent neutral proteinases from rabbit liver by an endogenous inhibitor. 105
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 105
Limited proteolysis of liver aldolase and fructose 1,6-bisphosphatase by lysosomal proteinases: effect on complex formation. 104
Mechanism of action of a new component of the ca2+dependent proteolytic system in rat brain:the calpain activator 103
Isolation and characterization of calpain activator protein from bovine brain. 103
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor. 103
Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides. Biochem. Biophys. Res. Commun. 193, 941-947 102
In vitro correction of erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiency. 102
Stimulation of erythroleukaemia cell differentiation by extracellular high mobility group-box protein 1 is independent of receptor for advanced glycation end products. 100
Proteolysis of human reticulocyte membrane proteins: evidence for a physiological role of the acid endopeptidases. 100
Selective proinflammatory activation of astrocytes by high mobility group box 1 protein signaling 100
Differentiation of HL60 promyelocytic cells is promoted by a "differentiation enhancing factor" produced by erythroleukemia cells" 99
Human neuroblastoma cell differentiation requires protein kinase C-θ 99
Role of phospholipids in the activation of the Ca2+-dependent neutral proteinase of human erythrocytes. 99
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 99
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 99
Localization of two lysosomal proteinases on the external surface of the lysosomal membrane. 98
Decay of proteinase and peptidase activities of human and rabbit erythrocytes during cellular aging. 98
Comparative patterns of 'in vitro' oxidative hemolysis of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient erythrocytes. 97
Characterization of three rabbit liver lysosomal proteinases with fructose 1,6-bisphosphatase converting enzyme activity. 96
Functional role of the charge at the T538 residue in the control of protein kinase Ctheta 95
Evidence for an interaction between fructose 1,6-bisphosphatase and fructose 1,6-bisphosphate aldolase. 94
Identification of proteolytic activities in the cytosolic compartment of mature human erythrocytes. 94
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 93
Erythrocyte deficiency in calpain inhibitor activity in essential hypertension. 93
Identification of an endogenous activator of calpain in rat skeletal muscle. 93
Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material. 93
Decreased level of calpain inhibitor activity in red blood cells from Milan hypertensive rats. 92
Phosphorylation of proteins in human neutrophils activated with phorbol myristate acetate or with chemotactic factor. 92
Interaction of rabbit liver cathepsin M and fructose 1,6-bisphosphatase converting enzyme with their endogenous inhibitors. 92
Cytolytic effects of neutrophils: role for a membrane-bound neutral proteinase. 91
Cytosolic calcium dependent neutral proteinase of human erythrocytes: the role of calcium ions on the molecular and catalytic properties of the enzyme. 90
Modulation of inhibitory efficiency of rat skeletal muscle calpastatin by phosphorylation. 90
Cytosolic Ca2+-dependent neutral proteinases from rabbit liver: activation of the proenzymes by Ca2+ and substrate. 90
Differences and similarities among three acidic endopeptidases associated with human erythrocyte membranes. Molecular and functional studies. 89
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells 88
Phosphorylation by protein kinase C of a 20-kDa cytoskeletal polypeptide enhances its susceptibility to digestion by calpain. 88
Role of δ-pkc on the differentiation process of murine erythroleukemia cells 87
Effects of a monoclonal anti-calpain antibody on responses of stimulated human neutrophils. Evidence for a role for proteolytically modified protein kinase C. 86
The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid. 84
An endogenous activator of the Ca2+-dependent proteinase of human neutrophils that increases its affinity for Ca2+. 84
The reversible activation by Mn2+ ions of the Ca2+-requiring neutral proteinase of human erythrocytes. 84
Following association to the membrane, human erythrocyte procalpain is converted and released as fully active calpain. 84
Neuronal differentiation of PC12 cells involves changes in protein kinase C-θ distribution and molecular properties. Biochem. Biophys. Res. Commun. 275, 149-153 83
Participation of protein kinase C in the activation of human neutrophils by phorbol ester 83
Characterization of the single peptide generated from the amino-terminus end of alpha- and beta-hemoglobin chains by the Ca2+-dependent neutral proteinase. 82
Enhanced activation of the respiratory burst oxidase in neutrophils from hypertensive patients. 82
Properties of calpastatin forms in rat brain 79
ATP induces the release of a neutral serine proteinase and enhances the production of superoxide anion in membranes from phorbol ester-activated neutrophils. 79
Differential mechanisms of translocation of protein kinase C to plasma membranes in activated human neutrophils. 76
Protein kinase C mRNA levels and activity in reconstituted normal human epidermis: relationships to cell differentiation. 76
Rat brain contains multiple mRNAs for calpastatin 76
HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration. 76
Totale 10.440
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Categoria #
all - tutte 27.731
article - articoli 26.097
book - libri 363
conference - conferenze 663
curatela - curatele 0
other - altro 0
patent - brevetti 193
selected - selezionate 0
volume - volumi 415
Totale 55.462
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019664 0 0 0 0 0 0 0 0 0 0 350 314
2019/20203.572 148 97 193 242 331 374 499 233 323 605 398 129
2020/2021809 45 82 50 53 48 91 43 66 78 96 83 74
2021/20221.421 36 92 65 198 49 123 117 282 64 153 58 184
2022/20231.472 135 81 8 192 244 298 1 93 276 10 122 12
2023/2024510 34 86 5 64 86 142 22 28 37 6 0 0
Totale 12.107