IRIS
SPARATORE, BIANCA
 Distribuzione geografica
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Continente #
EU - Europa 12.745
Totale 12.745
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Nazione #
IT - Italia 12.745
Totale 12.745
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Città #
Genova 10.039
Rapallo 1.248
Genoa 884
Vado Ligure 562
Bordighera 12
Totale 12.745
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 166
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 156
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 153
The calpain-calpastatin system in mammalian cells: properties and possible functions 151
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment 148
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 140
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 140
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 134
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 133
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 132
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 131
A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation 129
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 128
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain. 128
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 127
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 127
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes 126
Acyl-CoA-binding protein is a potent m-calpain activator 126
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 126
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 126
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 125
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 124
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NK p30 124
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 123
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 122
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 121
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 121
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 120
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 119
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 119
Selective Pro-Inflammatory Activation of Astrocytes by High Mobility Group Box 1 Protein Signaling 119
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 119
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 118
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 117
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 117
NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy? 117
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 116
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 116
High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo. 115
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 115
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 114
Introduction of beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells 112
The breakpoint identified in a balanced de novo translocation t(7;9)(p14.1;q31.3) disrupts the A-kinase (PRKA) anchor protein 2 gene (AKAP2) on chromosome 9 in a patient with Kallmann syndrome and bone anomalies 112
18β-Glycyrrhetic Acid Inhibits Immune Activation Triggered by HMGB1, a Pro-inflammatory Protein Found in the Tear Fluid during Conjunctivitis and Blepharitis. 112
Modulation of the intracellular Ca2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells 111
Endogenous inhibitors of lysosomal proteinases 111
Isolation and characterization of calpain activator protein from bovine brain. 110
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 109
Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation 109
Regulation of the Ca2+-dependent neutral proteinases from rabbit liver by an endogenous inhibitor. 108
Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides. Biochem. Biophys. Res. Commun. 193, 941-947 107
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor. 107
Limited proteolysis of liver aldolase and fructose 1,6-bisphosphatase by lysosomal proteinases: effect on complex formation. 107
Mechanism of action of a new component of the ca2+dependent proteolytic system in rat brain:the calpain activator 106
In vitro correction of erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiency. 106
Selective proinflammatory activation of astrocytes by high mobility group box 1 protein signaling 106
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 105
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 105
Differentiation of HL60 promyelocytic cells is promoted by a "differentiation enhancing factor" produced by erythroleukemia cells" 104
Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells 104
Stimulation of erythroleukaemia cell differentiation by extracellular high mobility group-box protein 1 is independent of receptor for advanced glycation end products. 104
Human neuroblastoma cell differentiation requires protein kinase C-θ 104
Proteolysis of human reticulocyte membrane proteins: evidence for a physiological role of the acid endopeptidases. 104
Localization of two lysosomal proteinases on the external surface of the lysosomal membrane. 104
Comparative patterns of 'in vitro' oxidative hemolysis of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient erythrocytes. 103
Role of phospholipids in the activation of the Ca2+-dependent neutral proteinase of human erythrocytes. 102
Decay of proteinase and peptidase activities of human and rabbit erythrocytes during cellular aging. 102
Functional role of the charge at the T538 residue in the control of protein kinase Ctheta 101
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 101
Interaction of rabbit liver cathepsin M and fructose 1,6-bisphosphatase converting enzyme with their endogenous inhibitors. 101
Characterization of three rabbit liver lysosomal proteinases with fructose 1,6-bisphosphatase converting enzyme activity. 100
Identification of proteolytic activities in the cytosolic compartment of mature human erythrocytes. 100
Changes in activity of fructose-1,6-bisphosphate aldolase in livers of fasted rabbits and accumulation of crossreacting immune material. 100
Cytolytic effects of neutrophils: role for a membrane-bound neutral proteinase. 97
Evidence for an interaction between fructose 1,6-bisphosphatase and fructose 1,6-bisphosphate aldolase. 97
Phosphorylation of proteins in human neutrophils activated with phorbol myristate acetate or with chemotactic factor. 97
Erythrocyte deficiency in calpain inhibitor activity in essential hypertension. 97
Identification of an endogenous activator of calpain in rat skeletal muscle. 96
Decreased level of calpain inhibitor activity in red blood cells from Milan hypertensive rats. 95
Differences and similarities among three acidic endopeptidases associated with human erythrocyte membranes. Molecular and functional studies. 95
Cytosolic calcium dependent neutral proteinase of human erythrocytes: the role of calcium ions on the molecular and catalytic properties of the enzyme. 94
Modulation of inhibitory efficiency of rat skeletal muscle calpastatin by phosphorylation. 93
The reversible activation by Mn2+ ions of the Ca2+-requiring neutral proteinase of human erythrocytes. 93
Characterization of the single peptide generated from the amino-terminus end of alpha- and beta-hemoglobin chains by the Ca2+-dependent neutral proteinase. 92
Cytosolic Ca2+-dependent neutral proteinases from rabbit liver: activation of the proenzymes by Ca2+ and substrate. 92
Phosphorylation by protein kinase C of a 20-kDa cytoskeletal polypeptide enhances its susceptibility to digestion by calpain. 91
An endogenous activator of the Ca2+-dependent proteinase of human neutrophils that increases its affinity for Ca2+. 91
Following association to the membrane, human erythrocyte procalpain is converted and released as fully active calpain. 90
Role of δ-pkc on the differentiation process of murine erythroleukemia cells 89
ATP induces the release of a neutral serine proteinase and enhances the production of superoxide anion in membranes from phorbol ester-activated neutrophils. 89
Effects of a monoclonal anti-calpain antibody on responses of stimulated human neutrophils. Evidence for a role for proteolytically modified protein kinase C. 88
Neuronal differentiation of PC12 cells involves changes in protein kinase C-θ distribution and molecular properties. Biochem. Biophys. Res. Commun. 275, 149-153 87
The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid. 87
Enhanced activation of the respiratory burst oxidase in neutrophils from hypertensive patients. 87
Participation of protein kinase C in the activation of human neutrophils by phorbol ester 86
Properties of calpastatin forms in rat brain 84
Protein kinase C mRNA levels and activity in reconstituted normal human epidermis: relationships to cell differentiation. 81
Differential mechanisms of translocation of protein kinase C to plasma membranes in activated human neutrophils. 80
A 6 kda protein homologous to the N-terminus of the HMG1 protein promoting stimulation of murine erytrolekemia cell differentiation. 80
Rat brain contains multiple mRNAs for calpastatin 80
Totale 11.033
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Categoria #
all - tutte 33.257
article - articoli 31.290
book - libri 404
conference - conferenze 841
curatela - curatele 0
other - altro 0
patent - brevetti 232
selected - selezionate 0
volume - volumi 490
Totale 66.514
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.892 0 0 0 0 331 374 499 233 323 605 398 129
2020/2021809 45 82 50 53 48 91 43 66 78 96 83 74
2021/20221.421 36 92 65 198 49 123 117 282 64 153 58 184
2022/20231.472 135 81 8 192 244 298 1 93 276 10 122 12
2023/2024613 34 86 5 64 86 142 22 28 37 6 33 70
2024/2025621 100 163 71 134 153 0 0 0 0 0 0 0
Totale 12.831