IRIS
CAFFA, IRENE
 Distribuzione geografica
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Continente #
EU - Europa 5.515
Totale 5.515
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Nazione #
IT - Italia 5.515
Totale 5.515
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Città #
Genova 3.866
Genoa 643
Rapallo 618
Vado Ligure 372
Bordighera 16
Totale 5.515
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Nome #
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 181
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 177
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 174
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 173
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 167
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 158
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice 145
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 144
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 143
Fasting and cancer: molecular mechanisms and clinical application 142
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells 140
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 140
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 133
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 132
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 132
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 131
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. 128
Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells 124
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 122
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 120
Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer. 119
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 118
Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice. 114
PHOX2B-mediated regulation of ALK expression: In vitro identification of a functional relationship between two genes involved in neuroblastoma 113
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 112
Nicotinic acid: A case for a vitamin that moonlights for cancer? 109
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 109
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives 108
Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma 105
Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors 101
Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status 100
Fasting plus tyrosine kinase inhibitors in cancer 97
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 94
Reply to 'Fasting in oncology: a word of caution' 90
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. 89
Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 89
Abstract CT075: Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects 88
Nutrients in the Prevention of Alzheimer's Disease 86
Development of a predictor of one-year mortality in older patients with cancer by geriatric and oncologic parameters 80
Synergistic Interaction Between P-glycoprotein Inhibitors and APO866 in Primary Leukemic Cells 78
Safety and feasibility of fasting‐mimicking diet and effects on nutritional status and circulating metabolic and inflammatory factors in cancer patients undergoing active treatment 74
Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model 70
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice 66
Quantitative Image Analysis Of Proliferation And Microvessels Density In A Mouse Xenograft Model Of Breast Cancer 62
Frailty assessment, hip fracture, and long-term clinical outcomes in older adults 50
Nicotinic acid phosphoribosyltransferase is overexpressed in solid tumors and regulates cancer cell metabolism and susceptibility to FK866 45
Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors 40
Cyclic fasting bolsters cholesterol biosynthesis inhibitors' anticancer activity 40
Effect of Geriatric Comanagement in Older Patients Undergoing Surgery for Gastrointestinal Cancer: A Retrospective, Before-and-After Study 37
Frailty assessment, hip fracture and long-term clinical outcomes in older adults 34
Enhancing endocrine therapy activity via fasting cycles: biological rationale and clinical feasibility 32
Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery 30
Author Correction: Cyclic fasting bolsters cholesterol biosynthesis inhibitors' anticancer activity 28
New Analogues of the Nicotinamide Phosphoribosyltransferase Inhibitor FK866 as Potential Anti-Pancreatic Cancer Agents 21
Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents 20
Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells 18
Author Correction: Fasting-mimicking diet and hormone therapy induce breast cancer regression 13
Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models 12
SENSITIZATION OF CANCER CELLS TO NAMPT INHIBITORS BY NICOTINIC ACID PHOSPHORIBOSYLTRANSFERASE NEUTRALIZATION 11
Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer 11
Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer 10
Dendritic cells direct circadian anti-tumour immune responses 10
Tyrosine kinase inhibitors for use in a method of treating cancer in association with a reduced caloric intake 9
Diet composition for the prevention and/or the treatment of endometrial hyperplasia 9
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. 8
Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells. 7
Fasting-mimicking diet and hormone therapy induce breast cancer regression 7
Use of a fasting mimicking diet to enhance the efficacy of antiestrogens in cancer therapy 6
Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers 4
Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in Neuroblastoma 3
Recent advances in targeted anti-vasculature therapy: the neuroblastoma model. 3
Totale 5.695
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Categoria #
all - tutte 18.350
article - articoli 17.875
book - libri 0
conference - conferenze 220
curatela - curatele 0
other - altro 0
patent - brevetti 255
selected - selezionate 0
volume - volumi 0
Totale 36.700
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.258 0 0 0 0 162 202 213 129 156 202 144 50
2020/2021618 35 59 81 35 53 34 16 70 51 86 58 40
2021/2022688 19 39 67 107 31 55 32 130 42 54 35 77
2022/2023741 70 69 7 91 122 99 5 60 111 6 93 8
2023/2024494 10 54 16 64 61 69 34 40 16 14 39 77
2024/2025451 97 95 30 128 101 0 0 0 0 0 0 0
Totale 5.695