CICHERO, ELENA
CICHERO, ELENA
100006 - Dipartimento di Farmacia
A family of nitrogen-containing heterocycles as sirtuin inhibitors: synthesis and invitro biological evaluation
2024-01-01 Falesiedi, M.; Scarano, N.; Grossi, G.; Carbone, A.; Brullo, C.; Musumeci, Francesca; Bruzzone, S.; Cichero, E.; Schenone, S.
Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors
2024-01-01 Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia.
Computational approaches for the design and chemical synthesis of novel F508del correctors in the treatment of cystic fibrosis
2018-01-01 Righetti, Giada; Liessi, N; Pesce, E; Pedemonte, N; Salis, A; Arkel, M; Spallarossa, A; Brullo, C; Tasso, B; Damonte, G; Millo, E; Fossa, P; Cichero, E.
Computational studies of the LANCL2 protein and abscissic acid towards the discovery of new ligands
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Spinelli, Sonia; Cavalli, Andrea; Cichero, Elena
In silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists
2024-01-01 Scarano, Naomi; Di Palma, Francesco; Spinelli, Sonia; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena
IN SILICO INVESTIGATION OF LANCL-2 ACTIVATION MECHANISM: THE CASE OF BT-11 (OMILANCOR).
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena
LEAD OPTIMIZATION OF MKT-077 ANALOGUES AS HSP70 ALLOSTERIC INHIBITORS COMBINED WITH F508DEL CFTR CORRECTORS: A MULTI DRUG APPROACH TO CONTRAST CYSTIC FIBROSIS
2024-01-01 Lunaccio, Dario; Garrone, Irene; Pesce, Emanuela; Caushi, Bujar; Salis, Annalisa; Pedemonte, Nicoletta; Sturla, Laura; Bruzzone, Santina; Cichero, Elena; Millo, Enrico
Pharmacophore and pharmacokinetic filtering tools guiding for the design and synthesis of novel thiazole-containing and VX-809 hybrid derivatives as F508del correctors.
2017-01-01 Liessi, N; Cichero, E; Pesce, E; Pedemonte, N; Salis, A; Arkel, M; Damonte, G; Spallarossa, A; Brullo, C; Fossa, P; Millo, E.
PYRAZOLO[3,4-d]PYRIMIDINE DERIVATIVES AS SIRTUIN INHIBITORS: DESIGN, SYNTHESIS AND PRELIMINARY in vitro EVALUATION
2024-01-01 Falesiedi, Marta; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia
RESCUING DEFECTIVE CFTR APPLYING A DRUG REPOSITIONING STRATEGY
2019-01-01 Uggeri, Matteo; Orro, A.; Urbinati, C.; Millo, E.; Cichero, E.; Paiardi, G.; Milanesi, L.; Pedemonte, N.; Rusnati, M.; D’Ursi, P.; Fossa, P.
Structure-Based Virtual Screening (SBVS) for the discovery of Sirtuin-2 inhibitors
2024-01-01 Scarano, Naomi; Musumeci, Francesca; Millo, Enrico; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena
Structure-Based Virtual Screening (SBVS) in flexible systems: the case of SIRT-2
2022-01-01 Scarano, Naomi; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A family of nitrogen-containing heterocycles as sirtuin inhibitors: synthesis and invitro biological evaluation | 1-gen-2024 | Falesiedi, M.; Scarano, N.; Grossi, G.; Carbone, A.; Brullo, C.; Musumeci, Francesca; Bruzzone, S.; Cichero, E.; Schenone, S. | |
| Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors | 1-gen-2024 | Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia. | |
| Computational approaches for the design and chemical synthesis of novel F508del correctors in the treatment of cystic fibrosis | 1-gen-2018 | Righetti, Giada; Liessi, N; Pesce, E; Pedemonte, N; Salis, A; Arkel, M; Spallarossa, A; Brullo, C; Tasso, B; Damonte, G; Millo, E; Fossa, P; Cichero, E. | |
| Computational studies of the LANCL2 protein and abscissic acid towards the discovery of new ligands | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Spinelli, Sonia; Cavalli, Andrea; Cichero, Elena | |
| In silico exploration of LANCL2-ABA binding mode towards the identification of novel LANCL2 agonists | 1-gen-2024 | Scarano, Naomi; Di Palma, Francesco; Spinelli, Sonia; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena | |
| IN SILICO INVESTIGATION OF LANCL-2 ACTIVATION MECHANISM: THE CASE OF BT-11 (OMILANCOR). | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Cavalli, Andrea; Musumeci, Francesca; Schenone, Silvia; Cichero, Elena | |
| LEAD OPTIMIZATION OF MKT-077 ANALOGUES AS HSP70 ALLOSTERIC INHIBITORS COMBINED WITH F508DEL CFTR CORRECTORS: A MULTI DRUG APPROACH TO CONTRAST CYSTIC FIBROSIS | 1-gen-2024 | Lunaccio, Dario; Garrone, Irene; Pesce, Emanuela; Caushi, Bujar; Salis, Annalisa; Pedemonte, Nicoletta; Sturla, Laura; Bruzzone, Santina; Cichero, Elena; Millo, Enrico | |
| Pharmacophore and pharmacokinetic filtering tools guiding for the design and synthesis of novel thiazole-containing and VX-809 hybrid derivatives as F508del correctors. | 1-gen-2017 | Liessi, N; Cichero, E; Pesce, E; Pedemonte, N; Salis, A; Arkel, M; Damonte, G; Spallarossa, A; Brullo, C; Fossa, P; Millo, E. | |
| PYRAZOLO[3,4-d]PYRIMIDINE DERIVATIVES AS SIRTUIN INHIBITORS: DESIGN, SYNTHESIS AND PRELIMINARY in vitro EVALUATION | 1-gen-2024 | Falesiedi, Marta; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia | |
| RESCUING DEFECTIVE CFTR APPLYING A DRUG REPOSITIONING STRATEGY | 1-gen-2019 | Uggeri, Matteo; Orro, A.; Urbinati, C.; Millo, E.; Cichero, E.; Paiardi, G.; Milanesi, L.; Pedemonte, N.; Rusnati, M.; D’Ursi, P.; Fossa, P. | |
| Structure-Based Virtual Screening (SBVS) for the discovery of Sirtuin-2 inhibitors | 1-gen-2024 | Scarano, Naomi; Musumeci, Francesca; Millo, Enrico; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena | |
| Structure-Based Virtual Screening (SBVS) in flexible systems: the case of SIRT-2 | 1-gen-2022 | Scarano, Naomi; Bruzzone, Santina; Schenone, Silvia; Cichero, Elena |