CICHERO, ELENA
CICHERO, ELENA
100006 - Dipartimento di Farmacia
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at alpha(1)-adrenoceptor subtypes and at 5-HT(1A) receptors.
2010-01-01 Franchini, S; Prandi, A; Baraldi, A; Sorbi, C; Tait, A; Buccioni, M; Marucci, G; Cilia, A; Pirona, L; Fossa, Paola; Cichero, Elena; Brasili, L.
3,4,5-Trisubstituted-1,2,4-4H-triazoles as WT and Y188L mutant HIV-1 non-nucleoside reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses.
2011-01-01 Cichero, Elena; Buffa, L; Fossa, Paola
Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses
2009-01-01 Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola
Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles
2017-01-01 Cichero, Elena; Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Delogu, I; Loddo, R.; Bruno, Olga; Fossa, Paola
Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation
2020-01-01 Saveri, Paola; De Luca, Maria; Nisi, Veronica; Pisciotta, Chiara; Romano, Roberta; Piscosquito, Giuseppe; Reilly, Mary M.; Polke, James M.; Cavallaro, Tiziana; Maria Fabrizi, Gian; Fossa, Paola; Cichero, Elena; Lombardi, Raffaella; Lauria, Giuseppe; Magri, Stefania; Taroni, Franco; Pareyson, Davide; Bucci, Cecilia
Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors
2024-01-01 Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia.
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists.
2010-01-01 Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola
CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists
2010-01-01 Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola
Computational approaches for the design and chemical synthesis of novel F508del correctors in the treatment of cystic fibrosis
2018-01-01 Righetti, Giada; Liessi, N; Pesce, E; Pedemonte, N; Salis, A; Arkel, M; Spallarossa, A; Brullo, C; Tasso, B; Damonte, G; Millo, E; Fossa, P; Cichero, E.
Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors
2009-01-01 Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola
Computational studies of the LANCL2 protein and abscissic acid towards the discovery of new ligands
2023-01-01 Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Spinelli, Sonia; Cavalli, Andrea; Cichero, Elena
Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del‐CFTR
2024-01-01 Spallarossa, Andrea; Pedemonte, Nicoletta; Pesce, Emanuela; Millo, Enrico; Cichero, Elena; Rosano, Camillo; Lusardi, Matteo; Iervasi, Erika; Ponassi, Marco
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists
2015-01-01 Chiellini, Grazia; Nesi, Giulia; Digiacomo, Maria; Malvasi, Rossella; Espinoza, Stefano; Sabatini, Martina; Frascarelli, Sabina; Laurino, Annunziatina; Cichero, Elena; Macchia, Marco; Gainetdinov, Raul R.; Fossa, Paola; Raimondi, Laura; Zucchi, Riccardo; Rapposelli, Simona
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling
2024-01-01 Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S.
Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays
2023-01-01 Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele
Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network
2022-01-01 Cichero, Elena
Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays
2020-01-01 Parodi, A.; Righetti, G.; Pesce, E.; Salis, A.; Tasso, B.; Urbinati, C.; Tomati, V.; Damonte, G.; Rusnati, M.; Pedemonte, N.; Cichero, E.; Millo, E.
Docking-based 3D-QSAR analyses of pyrazole derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
2012-01-01 Cichero, Elena; Fossa, Paola
Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors.
2012-01-01 Cichero, Elena; Bruno, Olga; Fossa, Paola
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1 and 5-HT1A receptor ligand: an in vitro and computational study
2015-01-01 Franchini, Silvia; Baraldi, Annamaria; Sorbi, Claudia; Pellati, Federica; Cichero, Elena; Battisti, Umbero M.; Angeli, Piero; Cilia, Antonio; Brasili, Livio
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at alpha(1)-adrenoceptor subtypes and at 5-HT(1A) receptors. | 1-gen-2010 | Franchini, S; Prandi, A; Baraldi, A; Sorbi, C; Tait, A; Buccioni, M; Marucci, G; Cilia, A; Pirona, L; Fossa, Paola; Cichero, Elena; Brasili, L. | |
3,4,5-Trisubstituted-1,2,4-4H-triazoles as WT and Y188L mutant HIV-1 non-nucleoside reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses. | 1-gen-2011 | Cichero, Elena; Buffa, L; Fossa, Paola | |
Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses | 1-gen-2009 | Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola | |
Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles | 1-gen-2017 | Cichero, Elena; Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Delogu, I; Loddo, R.; Bruno, Olga; Fossa, Paola | |
Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation | 1-gen-2020 | Saveri, Paola; De Luca, Maria; Nisi, Veronica; Pisciotta, Chiara; Romano, Roberta; Piscosquito, Giuseppe; Reilly, Mary M.; Polke, James M.; Cavallaro, Tiziana; Maria Fabrizi, Gian; Fossa, Paola; Cichero, Elena; Lombardi, Raffaella; Lauria, Giuseppe; Magri, Stefania; Taroni, Franco; Pareyson, Davide; Bucci, Cecilia | |
Combining repositioning and de novo synthesis of pyrazolo[3,4-d]pyrimidines to discover potent SIRT-2 inhibitors | 1-gen-2024 | Falesiedi, Marta; Scarano, Naomi; Grossi, Giancarlo; Carbone, Anna; Brullo, Chiara; Musumeci, Francesca; Bruzzone, Santina; Cichero, Elena; Schenone, Silvia. | |
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists. | 1-gen-2010 | Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola | |
CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists | 1-gen-2010 | Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola | |
Computational approaches for the design and chemical synthesis of novel F508del correctors in the treatment of cystic fibrosis | 1-gen-2018 | Righetti, Giada; Liessi, N; Pesce, E; Pedemonte, N; Salis, A; Arkel, M; Spallarossa, A; Brullo, C; Tasso, B; Damonte, G; Millo, E; Fossa, P; Cichero, E. | |
Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors | 1-gen-2009 | Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola | |
Computational studies of the LANCL2 protein and abscissic acid towards the discovery of new ligands | 1-gen-2023 | Scarano, Naomi; Di Palma, Francesco; Sturla, Laura; Spinelli, Sonia; Cavalli, Andrea; Cichero, Elena | |
Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del‐CFTR | 1-gen-2024 | Spallarossa, Andrea; Pedemonte, Nicoletta; Pesce, Emanuela; Millo, Enrico; Cichero, Elena; Rosano, Camillo; Lusardi, Matteo; Iervasi, Erika; Ponassi, Marco | |
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists | 1-gen-2015 | Chiellini, Grazia; Nesi, Giulia; Digiacomo, Maria; Malvasi, Rossella; Espinoza, Stefano; Sabatini, Martina; Frascarelli, Sabina; Laurino, Annunziatina; Cichero, Elena; Macchia, Marco; Gainetdinov, Raul R.; Fossa, Paola; Raimondi, Laura; Zucchi, Riccardo; Rapposelli, Simona | |
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling | 1-gen-2024 | Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S. | |
Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays | 1-gen-2023 | Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele | |
Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network | 1-gen-2022 | Cichero, Elena | |
Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays | 1-gen-2020 | Parodi, A.; Righetti, G.; Pesce, E.; Salis, A.; Tasso, B.; Urbinati, C.; Tomati, V.; Damonte, G.; Rusnati, M.; Pedemonte, N.; Cichero, E.; Millo, E. | |
Docking-based 3D-QSAR analyses of pyrazole derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors. | 1-gen-2012 | Cichero, Elena; Fossa, Paola | |
Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors. | 1-gen-2012 | Cichero, Elena; Bruno, Olga; Fossa, Paola | |
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1 and 5-HT1A receptor ligand: an in vitro and computational study | 1-gen-2015 | Franchini, Silvia; Baraldi, Annamaria; Sorbi, Claudia; Pellati, Federica; Cichero, Elena; Battisti, Umbero M.; Angeli, Piero; Cilia, Antonio; Brasili, Livio |