CICHERO, ELENA
CICHERO, ELENA
100006 - Dipartimento di Farmacia
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at alpha(1)-adrenoceptor subtypes and at 5-HT(1A) receptors.
2010-01-01 Franchini, S; Prandi, A; Baraldi, A; Sorbi, C; Tait, A; Buccioni, M; Marucci, G; Cilia, A; Pirona, L; Fossa, Paola; Cichero, Elena; Brasili, L.
3,4,5-Trisubstituted-1,2,4-4H-triazoles as WT and Y188L mutant HIV-1 non-nucleoside reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses.
2011-01-01 Cichero, Elena; Buffa, L; Fossa, Paola
Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses
2009-01-01 Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola
Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles
2017-01-01 Cichero, Elena; Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Delogu, I; Loddo, R.; Bruno, Olga; Fossa, Paola
Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation
2020-01-01 Saveri, Paola; De Luca, Maria; Nisi, Veronica; Pisciotta, Chiara; Romano, Roberta; Piscosquito, Giuseppe; Reilly, Mary M.; Polke, James M.; Cavallaro, Tiziana; Maria Fabrizi, Gian; Fossa, Paola; Cichero, Elena; Lombardi, Raffaella; Lauria, Giuseppe; Magri, Stefania; Taroni, Franco; Pareyson, Davide; Bucci, Cecilia
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists.
2010-01-01 Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola
CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists
2010-01-01 Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola
Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands
2024-01-01 Scarano, N.; Espinoza, S.; Brullo, C.; Cichero, E.
Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors
2009-01-01 Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola
Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del‐CFTR
2024-01-01 Spallarossa, Andrea; Pedemonte, Nicoletta; Pesce, Emanuela; Millo, Enrico; Cichero, Elena; Rosano, Camillo; Lusardi, Matteo; Iervasi, Erika; Ponassi, Marco
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists
2015-01-01 Chiellini, Grazia; Nesi, Giulia; Digiacomo, Maria; Malvasi, Rossella; Espinoza, Stefano; Sabatini, Martina; Frascarelli, Sabina; Laurino, Annunziatina; Cichero, Elena; Macchia, Marco; Gainetdinov, Raul R.; Fossa, Paola; Raimondi, Laura; Zucchi, Riccardo; Rapposelli, Simona
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling
2024-01-01 Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S.
Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays
2023-01-01 Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele
Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays
2024-01-01 Piacente, F.; Guccione, G.; Scarano, N.; Lunaccio, D.; Miro, C.; Abbotto, E.; Salis, A.; Tasso, B.; Dentice, M.; Bruzzone, S.; Cichero, E.; Millo, E.
Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network
2022-01-01 Bon, Carlotta; Chern, Ting-Rong; Cichero, Elena; E O'Brien, Terrence; Gustincich, Stefano; R Gainetdinov, Raul; Espinoza, Stefano
Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays
2020-01-01 Parodi, A.; Righetti, G.; Pesce, E.; Salis, A.; Tasso, B.; Urbinati, C.; Tomati, V.; Damonte, G.; Rusnati, M.; Pedemonte, N.; Cichero, E.; Millo, E.
Docking-based 3D-QSAR analyses of pyrazole derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
2012-01-01 Cichero, Elena; Fossa, Paola
Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors.
2012-01-01 Cichero, Elena; Bruno, Olga; Fossa, Paola
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1 and 5-HT1A receptor ligand: an in vitro and computational study
2015-01-01 Franchini, Silvia; Baraldi, Annamaria; Sorbi, Claudia; Pellati, Federica; Cichero, Elena; Battisti, Umbero M.; Angeli, Piero; Cilia, Antonio; Brasili, Livio
Exhaustive 3D-QSAR analyses as a computational tool to explore the potency and selectivity profiles of thieno[3,2-: D] pyrimidin-4(3 H)-one derivatives as PDE7 inhibitors
2016-01-01 Cichero, Elena; Brullo, Chiara; Bruno, Olga; Fossa, Paola
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at alpha(1)-adrenoceptor subtypes and at 5-HT(1A) receptors. | 1-gen-2010 | Franchini, S; Prandi, A; Baraldi, A; Sorbi, C; Tait, A; Buccioni, M; Marucci, G; Cilia, A; Pirona, L; Fossa, Paola; Cichero, Elena; Brasili, L. | |
| 3,4,5-Trisubstituted-1,2,4-4H-triazoles as WT and Y188L mutant HIV-1 non-nucleoside reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses. | 1-gen-2011 | Cichero, Elena; Buffa, L; Fossa, Paola | |
| Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses | 1-gen-2009 | Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola | |
| Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles | 1-gen-2017 | Cichero, Elena; Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Delogu, I; Loddo, R.; Bruno, Olga; Fossa, Paola | |
| Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation | 1-gen-2020 | Saveri, Paola; De Luca, Maria; Nisi, Veronica; Pisciotta, Chiara; Romano, Roberta; Piscosquito, Giuseppe; Reilly, Mary M.; Polke, James M.; Cavallaro, Tiziana; Maria Fabrizi, Gian; Fossa, Paola; Cichero, Elena; Lombardi, Raffaella; Lauria, Giuseppe; Magri, Stefania; Taroni, Franco; Pareyson, Davide; Bucci, Cecilia | |
| CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists. | 1-gen-2010 | Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola | |
| CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists | 1-gen-2010 | Cichero, Elena; Cesarini, Sara; Mosti, Luisa; Fossa, Paola | |
| Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands | 1-gen-2024 | Scarano, N.; Espinoza, S.; Brullo, C.; Cichero, E. | |
| Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors | 1-gen-2009 | Cichero, Elena; Cesarini, Sara; Spallarossa, Andrea; Mosti, Luisa; Fossa, Paola | |
| Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del‐CFTR | 1-gen-2024 | Spallarossa, Andrea; Pedemonte, Nicoletta; Pesce, Emanuela; Millo, Enrico; Cichero, Elena; Rosano, Camillo; Lusardi, Matteo; Iervasi, Erika; Ponassi, Marco | |
| Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists | 1-gen-2015 | Chiellini, Grazia; Nesi, Giulia; Digiacomo, Maria; Malvasi, Rossella; Espinoza, Stefano; Sabatini, Martina; Frascarelli, Sabina; Laurino, Annunziatina; Cichero, Elena; Macchia, Marco; Gainetdinov, Raul R.; Fossa, Paola; Raimondi, Laura; Zucchi, Riccardo; Rapposelli, Simona | |
| Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling | 1-gen-2024 | Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S. | |
| Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays | 1-gen-2023 | Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele | |
| Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays | 1-gen-2024 | Piacente, F.; Guccione, G.; Scarano, N.; Lunaccio, D.; Miro, C.; Abbotto, E.; Salis, A.; Tasso, B.; Dentice, M.; Bruzzone, S.; Cichero, E.; Millo, E. | |
| Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network | 1-gen-2022 | Bon, Carlotta; Chern, Ting-Rong; Cichero, Elena; E O'Brien, Terrence; Gustincich, Stefano; R Gainetdinov, Raul; Espinoza, Stefano | |
| Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays | 1-gen-2020 | Parodi, A.; Righetti, G.; Pesce, E.; Salis, A.; Tasso, B.; Urbinati, C.; Tomati, V.; Damonte, G.; Rusnati, M.; Pedemonte, N.; Cichero, E.; Millo, E. | |
| Docking-based 3D-QSAR analyses of pyrazole derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors. | 1-gen-2012 | Cichero, Elena; Fossa, Paola | |
| Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors. | 1-gen-2012 | Cichero, Elena; Bruno, Olga; Fossa, Paola | |
| Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1 and 5-HT1A receptor ligand: an in vitro and computational study | 1-gen-2015 | Franchini, Silvia; Baraldi, Annamaria; Sorbi, Claudia; Pellati, Federica; Cichero, Elena; Battisti, Umbero M.; Angeli, Piero; Cilia, Antonio; Brasili, Livio | |
| Exhaustive 3D-QSAR analyses as a computational tool to explore the potency and selectivity profiles of thieno[3,2-: D] pyrimidin-4(3 H)-one derivatives as PDE7 inhibitors | 1-gen-2016 | Cichero, Elena; Brullo, Chiara; Bruno, Olga; Fossa, Paola |