IRIS
ZOPPOLI, GABRIELE
 Distribuzione geografica
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Continente #
EU - Europa 10.572
Totale 10.572
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Nazione #
IT - Italia 10.572
Totale 10.572
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Città #
Genova 7.149
Genoa 1.393
Rapallo 1.336
Vado Ligure 657
Bordighera 37
Totale 10.572
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Nome #
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 178
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 177
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 175
P-334 * Radiological assessments for select patients in neoadjuvant setting in rectal cancer: monoinstitutional experience 173
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 160
A novel Bim-BH3-derived Bcl-X(L) inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity 158
Role of angiogenesis inhibitors in colorectal cancer: sensitive and insensitive tumors. 158
APO866 activity in hematologic malignancies: a preclinical in vitro study. 157
Impaired response to influenza vaccine associated with persistent memory B cell depletion in non-Hodgkin's lymphoma patients treated with rituximab-containing regimens. 155
DNA aneuploidy relationship with patient age and tobacco smoke in OPMDs/OSCCs 154
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 153
Ras-induced resistance to lapatinib is overcome by MEK inhibition 149
Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond. 147
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 144
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 143
Genomic DNA copy number aberrations, histological diagnosis, oral subsite and aneuploidy in OPMDs/OSCCs 143
Uncovering the genomic heterogeneity of multifocal breast cancer 142
Lymph node number, surface area and lymph node ratio are important prognostic indicators in neoadjuvant chemoradiotherapy treated rectal cancer 140
Abstract 986: Unraveling breast cancer progression through geographical and temporal sequencing 135
Abstract 49: Agreement of immunohistochemistry, fluorescence in situ hybridization, real-time quantitative polymerase-chain reaction, and quantitative reverse transcriptase PCR for Her-2/Neu status assessment in breast cancer patients: a single center, retrospective m 134
Seasonal and pandemic (A/H1N1 2009) MF-59-adjuvanted influenza vaccines in complete remission non-Hodgkin lymphoma patients previously treated with rituximab containing regimens. 133
Squalene epoxidase as a promising metabolic target in cancer treatment 132
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 132
Abstract A120: Cellular inhibition of Chk2 kinase and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 128
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 122
ANTITUMOR ACTIVITY OF NAMPT INHIBITION AND SYNERGY WITH CYCLOSPORIN A AND HDACIS TO PROMOTE APOPTOSIS IN PRIMARY LEUKEMIC CELLS 121
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 120
Abstract 4693: The putative DNA/RNA Helicase Schlafen-11 sensitizes cancer cells to topoisomerase I inhibitors 120
Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer 120
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 118
Quantitative Real Time PCR assessment of hormonal receptors and HER2 status on fine-needle aspiration pre-operatory specimens from a prospectively accrued cohort of women with suspect breast malignant lesions. 118
The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. 117
CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute. 117
Genomic Characterization of Primary Invasive Lobular Breast Cancer 116
Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis. 114
Polycythemia as rare secondary direct manifestation of acromegaly: management and single-centre epidemiological data. 112
Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases 110
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 110
Identification and Management of Immune Checkpoint Inhibitor-Related Myocarditis: Use Troponin Wisely 109
DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment. 108
Monotherapy with Pegylated Interferon Alpha-2a in Hemodialyzed Patients with Chronic Hepatitis C 108
Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC. 108
Circulating tumor DNA using tagged targeted deep sequencing to assess minimal residual disease in breast cancer patients undergoing neoadjuvant chemotherapy 108
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems 107
Patients Treated with Rituximab-Containing Immunochemotherapy Have a Significant and Prolonged Lack of Humoral Response to Influenza Vaccine Associated with a Persistent Depletion of B Memory Cells 105
Abstract S2-05: Characterization and clinical relevance of the genomic alterations defining lobular breast cancer: 105
Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents 104
Genomic aberrations in young and elderly breast cancer patients 104
Sequential dose-dense 5-fluorouracil, epirubicin and cyclophosphamide followed by docetaxel in patients with early breast cancer with four or more positive lymph nodes. 104
Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic 103
Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer 99
Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer. 98
Abstract 2116:CHEK2(Chk2) endogenous activation is associated with p53 deficiency and downregulation ofBRCA2and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60) 98
Gynaecomastia: the anastrozole paradox 97
On biomarkers and pathways in rectal cancer: What's the target? 95
Dynamic simulations of pathways downstream of TGF-beta , Wnt and EGF-family growth factors, in colorectal cancer, including mutations and treatments with onco-protein inhibitors 95
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 94
Paralytic ileus and liver failure-an unusual presentation of advanced erythropoietic protoporphyria 94
null 94
OMEGA (Offline Mutation Easy Genetic Annotator), a software analysis pipeline designed for thorough and easy annotation of NGS output 92
Pre-operative and pathologic assessment in neoadjuvant setting for rectal cancer: the experience of "RECOM Group". 92
Immune Infiltration in Invasive Lobular Breast Cancer 92
Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer 91
Relevance of HBV/HBcAb screening in lymphoma patients treated in the Rituximab era 90
Transcriptomic and genomic features of invasive lobular breast cancer 90
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. 90
Weekly standard doses of rh-EPO are highly effective for the treatment of anemic patients with low-intermediate 1 risk myelodysplastic syndromes. 90
Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 89
Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability. 88
Abstract CT075: Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects 88
Longer intervals after neoadjuvant therapy in locally advanced rectal cancer: a monocentric experience 86
The role of sentinel lymph node biopsy in patients with B5C breast cancer diagnosis 85
Impaired Humoral Response to Influenza Vaccine and Prolonged B Memory Cell Depletion as a Consequence of Rituximab-based Immunochemotherapy in non-Hodgkin Lymphoma Patients 83
Purpura as the initial presentation for small-cell lung cancer 82
Correction to: Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer (Breast Cancer Research and Treatment, (2019), 10.1007/s10549-019-05313-w) 82
Development of a predictor of one-year mortality in older patients with cancer by geriatric and oncologic parameters 80
Schlafen 11 Assessment in High-Grade Serous Ovarian Carcinoma: Phenotypic and Histological Distribution 79
Mutational analysis of BRCA1 and BRCA2 genes in high grade serous ovarian carcinoma with Next Generation Sequencing (NGS); correlation between somatic and germline mutations 76
Safety and feasibility of fasting‐mimicking diet and effects on nutritional status and circulating metabolic and inflammatory factors in cancer patients undergoing active treatment 74
Breast Cancer Surgery in the COVID-19 Pandemic: Validation of a Preventive Program for Patients and Health Care Workers 67
Tumor-to-nipple Distance Should Not Preclude Nipple-sparing Mastectomy in Breast Cancer Patients. Personal Experience and Literature Review 66
Standard Anthracycline-based versus Docetaxel-Capecitabine in early high clinical and/or genomic risk breast cancer in the EORTC 10041/ BIG 3-04 MINDACT phase III trial 65
Radiological assessment for select patients in neoadjuvant setting in rectal cancer: monoinstitutional experience 64
Potent Synergistic Activity of the NAD plus Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia. 63
Depletion of the intracellular coenzyme NAD plus in activated T-cells ameliorates experimental autoimmune encephalomyelitis 63
Iodized oil pleural effusion in a patient previously treated with transarterial chemoembolization for hepatocellular carcinoma 60
Transcriptome Sequencing Of The Transition From Normal Epithelium To Invasive Cancer Reveals Insights Into The Carcinogenesis Of Hpv+ And Hpv- Vulvar Neoplasia 60
Sterol synthesis pathway inhibition as a target for cancer treatment 59
70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age 59
Development of a hoRizontal data intEgration classifier for NOn-invasive early diAgnosis of breasT cancEr: the RENOVATE study protocol 58
Development of a long non-coding RNA signature for prediction of response to neoadjuvant chemoradiotherapy in locally advanced rectal adenocarcinoma 53
Novel imaging techniques and biological methods for breast cancer evaluation: overview and update 51
The genomic landscape of metastatic histologic special types of invasive breast cancer 45
Assessment of circulating nucleic acids in cancer: From current status to future perspectives and potential clinical applications 45
Plasma Cell-Free DNA Integrity Assessed by Automated Electrophoresis Predicts the Achievement of Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer 45
Clinical and Radiological Predictors of Biochemical Response to First-Line Treatment With Somatostatin Receptor Ligands in Acromegaly: A Real-Life Perspective 42
Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative 41
May standard basal echocardiogram allow to obtain predictors of asymptomatic cardiac dysfunction in alcoholics? 39
A modular framework for the development of targeted Covid-19 blood transcript profiling panels 38
Digital analysis of distant and cancer-associated mammary adipocytes 37
Totale 10.211
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Categoria #
all - tutte 37.460
article - articoli 36.286
book - libri 0
conference - conferenze 551
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 623
Totale 74.920
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.114 0 0 0 0 225 304 387 218 261 390 254 75
2020/20211.042 64 79 102 99 130 68 44 86 85 114 95 76
2021/20221.393 62 75 110 177 72 91 71 302 80 132 71 150
2022/20231.640 161 165 13 181 257 211 26 131 256 7 208 24
2023/20241.063 42 124 24 127 97 202 44 85 53 35 71 159
2024/2025757 141 174 74 206 162 0 0 0 0 0 0 0
Totale 10.805