IRIS
ZOPPOLI, GABRIELE
 Distribuzione geografica
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Continente #
EU - Europa 9.754
Totale 9.754
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Nazione #
IT - Italia 9.754
Totale 9.754
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Città #
Genova 7.231
Rapallo 1.384
Genoa 1.101
Bordighera 38
Totale 9.754
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Nome #
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 171
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 169
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 164
P-334 * Radiological assessments for select patients in neoadjuvant setting in rectal cancer: monoinstitutional experience 162
Role of angiogenesis inhibitors in colorectal cancer: sensitive and insensitive tumors. 149
Dynamic simulations of pathways downstream of TGF-β , Wnt and EGF-family grow- th factors, in colorectal cancer, including mutations and treatments with onco-protein inhibitors 147
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 147
A novel Bim-BH3-derived Bcl-X(L) inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity 143
APO866 activity in hematologic malignancies: a preclinical in vitro study. 143
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 142
Impaired response to influenza vaccine associated with persistent memory B cell depletion in non-Hodgkin's lymphoma patients treated with rituximab-containing regimens. 142
Ras-induced resistance to lapatinib is overcome by MEK inhibition 140
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 139
Genomic DNA copy number aberrations, histological diagnosis, oral subsite and aneuploidy in OPMDs/OSCCs 138
Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond. 137
Uncovering the genomic heterogeneity of multifocal breast cancer 137
DNA aneuploidy relationship with patient age and tobacco smoke in OPMDs/OSCCs 133
Lymph node number, surface area and lymph node ratio are important prognostic indicators in neoadjuvant chemoradiotherapy treated rectal cancer 131
Seasonal and pandemic (A/H1N1 2009) MF-59-adjuvanted influenza vaccines in complete remission non-Hodgkin lymphoma patients previously treated with rituximab containing regimens. 130
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 128
Abstract 986: Unraveling breast cancer progression through geographical and temporal sequencing 127
Abstract 49: Agreement of immunohistochemistry, fluorescence in situ hybridization, real-time quantitative polymerase-chain reaction, and quantitative reverse transcriptase PCR for Her-2/Neu status assessment in breast cancer patients: a single center, retrospective m 126
Squalene epoxidase as a promising metabolic target in cancer treatment 125
Abstract A120: Cellular inhibition of Chk2 kinase and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 123
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 123
CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute. 116
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 115
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 112
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 111
Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer 111
Abstract 4693: The putative DNA/RNA Helicase Schlafen-11 sensitizes cancer cells to topoisomerase I inhibitors 110
Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis. 110
Genomic Characterization of Primary Invasive Lobular Breast Cancer 110
Quantitative Real Time PCR assessment of hormonal receptors and HER2 status on fine-needle aspiration pre-operatory specimens from a prospectively accrued cohort of women with suspect breast malignant lesions. 110
ANTITUMOR ACTIVITY OF NAMPT INHIBITION AND SYNERGY WITH CYCLOSPORIN A AND HDACIS TO PROMOTE APOPTOSIS IN PRIMARY LEUKEMIC CELLS 109
Polycythemia as rare secondary direct manifestation of acromegaly: management and single-centre epidemiological data. 109
The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. 108
Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC. 105
Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases 104
DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment. 103
Monotherapy with Pegylated Interferon Alpha-2a in Hemodialyzed Patients with Chronic Hepatitis C 103
Identification and Management of Immune Checkpoint Inhibitor-Related Myocarditis: Use Troponin Wisely 103
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 102
Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents 101
Genomic aberrations in young and elderly breast cancer patients 101
Patients Treated with Rituximab-Containing Immunochemotherapy Have a Significant and Prolonged Lack of Humoral Response to Influenza Vaccine Associated with a Persistent Depletion of B Memory Cells 100
Abstract S2-05: Characterization and clinical relevance of the genomic alterations defining lobular breast cancer: 98
Circulating tumor DNA using tagged targeted deep sequencing to assess minimal residual disease in breast cancer patients undergoing neoadjuvant chemotherapy 98
Sequential dose-dense 5-fluorouracil, epirubicin and cyclophosphamide followed by docetaxel in patients with early breast cancer with four or more positive lymph nodes. 97
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems 95
null 94
On biomarkers and pathways in rectal cancer: What's the target? 93
Abstract 2116:CHEK2(Chk2) endogenous activation is associated with p53 deficiency and downregulation ofBRCA2and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60) 93
Gynaecomastia: the anastrozole paradox 91
Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic 91
Immune Infiltration in Invasive Lobular Breast Cancer 90
Paralytic ileus and liver failure-an unusual presentation of advanced erythropoietic protoporphyria 88
Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer 88
HDAC INHIBITORS SYNERGISTICALLY ENHANCE AP0866 ACTIVITY IN HUMAN LEUKEMIA CELLS: EVIDENCE FOR CONVERGING MECHANISMS OF SIRT1 INHIBITION 87
Relevance of HBV/HBcAb screening in lymphoma patients treated in the Rituximab era 87
Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer. 86
Transcriptomic and genomic features of invasive lobular breast cancer 86
Weekly standard doses of rh-EPO are highly effective for the treatment of anemic patients with low-intermediate 1 risk myelodysplastic syndromes. 86
OMEGA (Offline Mutation Easy Genetic Annotator), a software analysis pipeline designed for thorough and easy annotation of NGS output 85
Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability. 85
Pre-operative and pathologic assessment in neoadjuvant setting for rectal cancer: the experience of "RECOM Group". 84
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. 83
Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 82
Impaired Humoral Response to Influenza Vaccine and Prolonged B Memory Cell Depletion as a Consequence of Rituximab-based Immunochemotherapy in non-Hodgkin Lymphoma Patients 78
Purpura as the initial presentation for small-cell lung cancer 77
The role of sentinel lymph node biopsy in patients with B5C breast cancer diagnosis 77
Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer 76
Longer intervals after neoadjuvant therapy in locally advanced rectal cancer: a monocentric experience 76
Abstract CT075: Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects 75
Correction to: Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer (Breast Cancer Research and Treatment, (2019), 10.1007/s10549-019-05313-w) 74
Schlafen 11 Assessment in High-Grade Serous Ovarian Carcinoma: Phenotypic and Histological Distribution 71
Development of a predictor of one-year mortality in older patients with cancer by geriatric and oncologic parameters 68
Fasting-mimicking diet and hormone therapy induce breast cancer regression 67
Mutational analysis of BRCA1 and BRCA2 genes in high grade serous ovarian carcinoma with Next Generation Sequencing (NGS); correlation between somatic and germline mutations 67
Safety and feasibility of fasting‐mimicking diet and effects on nutritional status and circulating metabolic and inflammatory factors in cancer patients undergoing active treatment 61
Standard Anthracycline-based versus Docetaxel-Capecitabine in early high clinical and/or genomic risk breast cancer in the EORTC 10041/ BIG 3-04 MINDACT phase III trial 59
Radiological assessment for select patients in neoadjuvant setting in rectal cancer: monoinstitutional experience 57
Potent Synergistic Activity of the NAD plus Synthesis Inhibitor APO866 and of the Apoptosis Inducer TRAIL in in Vitro and Ex Vivo Cellular Models of Non Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia. 56
Transcriptome Sequencing Of The Transition From Normal Epithelium To Invasive Cancer Reveals Insights Into The Carcinogenesis Of Hpv+ And Hpv- Vulvar Neoplasia 54
Tumor-to-nipple Distance Should Not Preclude Nipple-sparing Mastectomy in Breast Cancer Patients. Personal Experience and Literature Review 54
Breast Cancer Surgery in the COVID-19 Pandemic: Validation of a Preventive Program for Patients and Health Care Workers 54
Depletion of the intracellular coenzyme NAD plus in activated T-cells ameliorates experimental autoimmune encephalomyelitis 53
Iodized oil pleural effusion in a patient previously treated with transarterial chemoembolization for hepatocellular carcinoma 52
70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age 51
Sterol synthesis pathway inhibition as a target for cancer treatment 50
Development of a hoRizontal data intEgration classifier for NOn-invasive early diAgnosis of breasT cancEr: the RENOVATE study protocol 49
Development of a long non-coding RNA signature for prediction of response to neoadjuvant chemoradiotherapy in locally advanced rectal adenocarcinoma 45
Novel imaging techniques and biological methods for breast cancer evaluation: overview and update 45
Plasma Cell-Free DNA Integrity Assessed by Automated Electrophoresis Predicts the Achievement of Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer 38
The genomic landscape of metastatic histologic special types of invasive breast cancer 37
Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative 36
Clinical and Radiological Predictors of Biochemical Response to First-Line Treatment With Somatostatin Receptor Ligands in Acromegaly: A Real-Life Perspective 36
Fasting-mimicking diet and hormone therapy induce breast cancer regression 36
Assessment of circulating nucleic acids in cancer: From current status to future perspectives and potential clinical applications 33
A modular framework for the development of targeted Covid-19 blood transcript profiling panels 32
Totale 9.530
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Categoria #
all - tutte 30.130
article - articoli 29.244
book - libri 0
conference - conferenze 368
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 518
Totale 60.260
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019533 0 0 0 0 0 0 0 0 0 105 225 203
2019/20202.575 109 59 96 186 227 305 393 218 263 389 254 76
2020/20211.067 63 81 110 99 131 72 44 90 89 116 95 77
2021/20221.409 62 78 110 176 75 91 72 307 81 134 73 150
2022/20231.696 163 170 13 187 262 216 29 142 262 11 217 24
2023/2024861 51 126 25 132 101 208 41 88 54 35 0 0
Totale 9.982