We report two cases of Schnitzler's syndrome in which anti-interleukin-1 alpha autoantibodies and functional autoantibodies against the high affinity IgE receptor (Fc epsilon RI alpha) or against IgE were absent. One patient responded well to TL-01 phototherapy, a treatment which may be considered in patients with Schnitzler's syndrome if, as is usually the case, they are unresponsive to antihistamine therapy.
Schnitzler's syndrome: No evidence for autoimmune basis in two patients
Gallo R.;
2000-01-01
Abstract
We report two cases of Schnitzler's syndrome in which anti-interleukin-1 alpha autoantibodies and functional autoantibodies against the high affinity IgE receptor (Fc epsilon RI alpha) or against IgE were absent. One patient responded well to TL-01 phototherapy, a treatment which may be considered in patients with Schnitzler's syndrome if, as is usually the case, they are unresponsive to antihistamine therapy.
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