Study of efficacy and safety of rucinol and sophora alpha in the topical treatment of cutaneous hypermelanoses

Cutaneous hypermelanoses are usually the result of an increased epidermal or dermal melanin pigmentation. Inflammatory processes and sun light exposure are the most frequent causes of the acquired skin hyperpigmentations. In this article we review the results of four years clinical experience of a new bleaching agent containing rucinol serum 0.3% and sophora alpha 1%. This compound was applied as monotherapy or combined with chemical peel or laser therapy in more than 300 patients with acquired skin hyperptmentations. The results show that rucinol serum 0.3% plus sophora alpha 1% is effective and safe in improving acquired skin hyperpigmentations both in monotherapy and combined with chemical peel or laser therapy.