New Insights on the Relation Between Human Microbiota and Food Allergy

Food allergy onset occurs in early life, in fact an Australian non-selected 1-year-old children cohort showed a prevalence of sesame, peanut and egg allergy of 8.9, 3.0 and 0.8 % respectively. Other experiments showed that clinical reactivity to such foods arises around 4 months of age. Several researchers reported dysbiosis in food allergic subjects. Some studies about human microbiome genetics evidenced altered gut microbiota in individuals suffering from both cow’s milk and egg allergies. It is generally accepted that dysbiosis arises prodromal to the food allergy onset. In fact, after analyzing gut microbiota in children, belonging to a Canadian cohort, within 12 months of age, it was found proof of food sensitization after 12 months of age. The aim of this opinion paper is to enforce existing evidences and, above all, to introduce the concept that, in many cases, human features and perceptions are mostly shaped by microbiota, as outlined in my previous papers.