Photodynamic therapy (PDT) is a tumor treatment that uses a combination of otherwise non-toxic chemicals, termed photosensitizers (PSs) and visible light to produce reactive oxygen species capable of destroying tumor cells [Dougherty TJ (1993)][Agostinis P. et al.(2011)].PS molecules are often insoluble in water and form aggregates, which impairs their photophysical properties, generally resulting in a quenching of the productive excited states. To overcome this limit, PSs carriers have been devised [Bechet D. et al.(2008)][Konan, YN et al.(2002)].
Study of Tumor Cellular Damage Induced by Photosensitizing Molecules
Cozzolino, Marco;Pesce, Luca;Bianchini, Paolo;Diaspro, Alberto
2018-01-01
Abstract
Photodynamic therapy (PDT) is a tumor treatment that uses a combination of otherwise non-toxic chemicals, termed photosensitizers (PSs) and visible light to produce reactive oxygen species capable of destroying tumor cells [Dougherty TJ (1993)][Agostinis P. et al.(2011)].PS molecules are often insoluble in water and form aggregates, which impairs their photophysical properties, generally resulting in a quenching of the productive excited states. To overcome this limit, PSs carriers have been devised [Bechet D. et al.(2008)][Konan, YN et al.(2002)].
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