Recent results in biomedical engineering and materials science and technology have brought about the development of novel bioactive materials by which the repair of peripheral nervous system injuries can be improved. The formation of scarring tissue, which represents a physical barrier to axon elongation, and the not oriented outgrowth of neurites are the two major obstacles for a complete recovery of physiological nerve function. This study mainly focuses on the analysis of biocompatible constructs for the controlled release of anti-scarring antibodies by means of fluorescence spectroscopy techniques.
A drug delivery system for the treatment of peripheral nervous system injuries
CANEVA SOUMETZ, FEDERICO;GIACOMINI, MAURO;RUGGIERO, CARMELINA
2004-01-01
Abstract
Recent results in biomedical engineering and materials science and technology have brought about the development of novel bioactive materials by which the repair of peripheral nervous system injuries can be improved. The formation of scarring tissue, which represents a physical barrier to axon elongation, and the not oriented outgrowth of neurites are the two major obstacles for a complete recovery of physiological nerve function. This study mainly focuses on the analysis of biocompatible constructs for the controlled release of anti-scarring antibodies by means of fluorescence spectroscopy techniques.
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