The preparation of 3-alkyl-4-(chloromethyl)-1-RSO2-1H-pyrrol-2(5H)-ones was efficiently accomplished through a [1,2]-elimination of -lactams derived from the copper (I)-catalysed ATRC of 2,2-dichloro-N-(2-chloroallyl)-N-RSO2-amides. The two reactions can be integrated into a sequential one-pot process.
Synthesis of 3-alkyl-4-(chloromethyl)-3-alkyl-1-RSO2-1H-pyrrol-2(5H)-ones, using a sequential ATRC/[1,2]-elimination, from 2,2-dichloro-N-(2-chloroallyl)-N-RSO2-amides
PETRILLO, GIOVANNI;
2011-01-01
Abstract
The preparation of 3-alkyl-4-(chloromethyl)-1-RSO2-1H-pyrrol-2(5H)-ones was efficiently accomplished through a [1,2]-elimination of -lactams derived from the copper (I)-catalysed ATRC of 2,2-dichloro-N-(2-chloroallyl)-N-RSO2-amides. The two reactions can be integrated into a sequential one-pot process.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
