A small set of 9-(lupinylthio)xanthene, -thioxanthenes and α-(lupinylthio)diphenylmethanes was prepared and found to inhibit the angiotensin II-induced contractions of guinea pig ileum. Some of these compounds were also moderately active in vitro as tracheal relaxants and one compound was more active than aspirin against arachidonic acid-induced platelet aggregation.

Synthesis and pharmacological evaluation of some thiolupinine derivatives

NOVELLI, FEDERICA;TASSO, BRUNO;SPARATORE, FABIO
1999

Abstract

A small set of 9-(lupinylthio)xanthene, -thioxanthenes and α-(lupinylthio)diphenylmethanes was prepared and found to inhibit the angiotensin II-induced contractions of guinea pig ileum. Some of these compounds were also moderately active in vitro as tracheal relaxants and one compound was more active than aspirin against arachidonic acid-induced platelet aggregation.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11567/247274
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