Diabetic cardiomyopathy (DbCM) is characterized by restrictive pattern and consistent risk of overt heart failure. We here focused osteopontin (OPN), which was tested independently associated with left ventricular diastolic dysfunction (LVDD). Overall, OPN increased with DbCM severity according with the presence of left atrial dilatation, LV hypertrophy and LVDD.
Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes
Scuricini, Alessandro;Sgura, Cosimo;Bertolotto, Maria;Ramoni, Davide;Liberale, Luca;Montecucco, Fabrizio;Carbone, Federico
2023-01-01
Abstract
Diabetic cardiomyopathy (DbCM) is characterized by restrictive pattern and consistent risk of overt heart failure. We here focused osteopontin (OPN), which was tested independently associated with left ventricular diastolic dysfunction (LVDD). Overall, OPN increased with DbCM severity according with the presence of left atrial dilatation, LV hypertrophy and LVDD.
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