This letter presents a low-cost, lightweight, and automatic readout system for accurate quantification of cisplatin (Cis-Pt) level in a colorimetric POC device. The system relies on an RGB camera to record the color changes in the test tube and an inference function trained via machine learning techniques to estimate Cis-Pt concentration. A suitable training strategy for ensemble learning is adopted to deal with a scenario involving a small training set. In addition, the training strategy is designed to support a gray-box model, thus enabling interpretability. Experimental results show that the readout system based on the proposed strategy is able to outperform the state-of-the-art readout system for the quantification of Cis-Pt level in a colorimetric POC device.

Design of a quantitative readout in a point of care device for cisplatin detection

Edoardo Ragusa;Rodolfo Zunino;Paolo Gastaldo
2022-01-01

Abstract

This letter presents a low-cost, lightweight, and automatic readout system for accurate quantification of cisplatin (Cis-Pt) level in a colorimetric POC device. The system relies on an RGB camera to record the color changes in the test tube and an inference function trained via machine learning techniques to estimate Cis-Pt concentration. A suitable training strategy for ensemble learning is adopted to deal with a scenario involving a small training set. In addition, the training strategy is designed to support a gray-box model, thus enabling interpretability. Experimental results show that the readout system based on the proposed strategy is able to outperform the state-of-the-art readout system for the quantification of Cis-Pt level in a colorimetric POC device.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11567/1141935
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact