Parkinson's disease (PD) is characterized by a neurodegenerative process, which has been previously reported to involve some retinal layers, in particular the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (mGCC). When measuring pRNFL and mGCC by Optical Coherence Tomography in PD patients, it should not be neglected the role of possible both sistemic and intraocular factors, which have been proven to modify intraretinal thicknesses measurements. Nonetheless, also dopaminergic drugs administration could represent another important confounding factor, given their neuroprotective effect exerted on retina.
Systemic and intraocular factors related to retinal thicknesses variations in patients with Parkinson's disease
Ferro Desideri L.;Barra F.;Ferrero S.
2019-01-01
Abstract
Parkinson's disease (PD) is characterized by a neurodegenerative process, which has been previously reported to involve some retinal layers, in particular the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (mGCC). When measuring pRNFL and mGCC by Optical Coherence Tomography in PD patients, it should not be neglected the role of possible both sistemic and intraocular factors, which have been proven to modify intraretinal thicknesses measurements. Nonetheless, also dopaminergic drugs administration could represent another important confounding factor, given their neuroprotective effect exerted on retina.
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