Serum (1,3)-beta-d-glucan (BDG) assay is a non-culture-based test recommended for the diagnosis of invasive candidiasis owing to its faster results and higher sensitivity than blood cultures. Its performance might vary for different Candida species. The aim of this study was to determine in vitro levels of BDG in Candida auris culture supernatants and evaluate BDG levels in patients with C. auris candidemia sustained by these stains.
Levels of beta-D-glucan in Candida auris supernatants, an in vitro and in vivo preliminary study
Mikulska, Malgorzata;Furfaro, Elisa;Magnasco, Laura;Codda, Giulia;Giacobbe, Daniele Roberto;Dentone, Chiara;Vena, Antonio;Marchese, Anna;Bassetti, Matteo
2022-01-01
Abstract
Serum (1,3)-beta-d-glucan (BDG) assay is a non-culture-based test recommended for the diagnosis of invasive candidiasis owing to its faster results and higher sensitivity than blood cultures. Its performance might vary for different Candida species. The aim of this study was to determine in vitro levels of BDG in Candida auris culture supernatants and evaluate BDG levels in patients with C. auris candidemia sustained by these stains.
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