Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials

Charles, C Wykoff; Abreu, Francis; Anthony, P Adamis; Basu, Karen; David, A Eichenbaum; Haskova, Zdenka; Lin, Hugh; Loewenstein, Anat; Mohan, Shaun; Ian, A Pearce; Sakamoto, Taiji; Patricio, G Schlottmann; Silverman, David; Jennifer, K Sun; John, A Wells; Jeffrey, R Willis; Tadayoni, Ramin; Thomas Aaberg Jr,; Abbey, Ashkan; Abdulaeva, Elmira; Abengoechea, Santiago; Abraham, Prema; Ach, Thomas; Adams, Serrhel; Alfredo Adan Civera,; Adrean, Sean; Agostini, Hansjurgen; Alam, Suhail; Alezzandrini, Arturo; Alfaro, Virgil; Aliseda, Daniel; Almony, Arghavan; Amat, Pedro; Amini, Payam; Antoszyk, Andrew; Arias, Luis; Asaria, Riaz; Avila, Marcos; Carl, C Awh; Bafalluy, Joaquin; Baker, Carl; Bandello, Francesco; Barakat, Mark; Barraza, Karen; Bator, Gyorgy; Baumal, Caroline; Rubens Belfort Jr,; Bergstrom, Chris; Bertolucci, George; Bochow, Thomas; Bolz, Matthias; Borcz, Emilia; Bordon, Arnaldo; Boyer, David; Bratko, Galina; Brent, Michael; Brown, Jamin; David, M Brown; Budzinskaya, Maria; Buffet, Sylvia; Burgess, Stuart; Burton, Ben; Busquets, Miguel; Cabrera, Francisco; Cagini, Carlo; Calzada, Jorge; Campochiaro, Peter; Carlson, John; Castellarin, Alessandro; Cava, Carlos; Chaikitmongkol, Voraporn; Chan, Clement; Chang, Emmanuel; Chang, Jonathan; Chang, Andrew; Charles, Steve; Chaudhry, Nauman; Chee, Caroline; Chen, Judy; Chen, Fred; Chen, Shih-Jen; Cheong-Leen, Richard; Chiang, Allen; Chittum, Mark; Chow, David; Connolly, Brian; Pierre Loic Cornut,; Csaky, Karl; Danzig, Carl; Das, Arup; Daskalov, Vesselin; Desco, Carmen; Dessouki, Amr; Dickinson, John; Brian, Do; Dollin, Michael; Dugel, Pravin; Dusova, Jaroslava; Eichenbaum, David; Eldem, Bora; Engstrom, Robert; Ernest, Jan; Joan Josep Escobar,; Esposti, Simona; Eter, Nicole; Falk, Naomi; Farkas, Andrej; Feiner, Leonard; Feltgen, Nicolas; Fernandez, Carlos; Alvaro Fernandez Vega,; Ferrone, Philip; Figueira, Joao; Figueroa, Marta; Findl, Oliver; Fine, Howard; Fortun, Jorge; Gregory, M Fox; Foxman, Scott; Framme, Carsten; Fraser-Bell, Samantha; Arthur, Fu; Fukutomi, Akira; Fung, Nicholas; Federico Furno Sola,; Gallego-Pinazo, Roberto; Garcia, Renata; Garcia-Layana, Alfredo; Gawecki, Maciej; George, Sheen; Ghanchi, Faruque; Ghorayeb, Ghassan; Goldberg, Roger; Goldstein, Michaella; Gomes, Nuno; Francisco Gomez Ulla,; Gonzalez, Victor; Greven, Craig; Gupta, Sunil; Guzman, Miguel; Harris, Martin; Hatz, Katja; Hau, Vivienne; Hau, Vincent; Hayashi, Ken; Heier, Jeffrey; Herba, Ewa; Hershberger, Vrinda; Higgins, Patrick; Hirakata, Akito; Allen, Ho; Holekamp, Nancy; Honda, Shigeru; Hsu, Jason; Allen, Hu; Hurcikova, Maria; Ikeda, Yasuhiro; Isernhagen, Ricky; Ito, Yasuki; Jackson, Tim; Jacoby, Rachael; Jafree, Afsar; Javey, Golnaz; Javid, Cameron; Jhaveri, Chirag; Johnson, Mark; Kacerík, Marek; Kaluzny, Jakub; Kampik, Daniel; Se Woong Kang,; Kapoor, Kapil; Karabas, Levent; Kawasaki, Tsutomu; Kerenyi, Agnes; Khanani, Arshad; Khurana, Rahul; Kim, Brian; Kimura, Kazuhiro; Kishino, Genichiro; Kitano, Shigehiko; Klein-Mascia, Kendra; Kokame, Gregg; Jean Francois Korobelnik,; Kulikov, Alexey; Kuriyan, Ajay; Kwong, Henry; Kwun, Robert; Lai, Timothy; Lai, Chi-Chun; Laird, Philip; Lalonde, Laurent; Lanzetta, Paolo; Larsen, Michael; Laugesen, Caroline; Lavinsky, Daniel; Lebreton, Olivier; Lee, Seong; Levy, Jaime; Lipkova, Blandina; Liu, Mimi; Liu, Judy; Chris, P Lohmann; London, Nikolas; Lorenz, Katrin; Lotery, Andrew; David Lozano Rechy,; Lujan, Silvio; Patrick, Ma; Maeno, Takatoshi; Mahmood, Sajjad; Makkouk, Fuad; Malik, Khurram; Marcus, Dennis; Margherio, Alan; Mastropasqua, Leonardo; Maturi, Raj; Mccabe, Frank; Mckibbin, Martin; Mehta, Hemal; Menon, Geeta; Mentes, Jale; Michalska-Malecka, Katarzyna; Misheva, Aneta; Mitamura, Yoshinori; Mitchell, Paul; Modi, Yasha; Mohamed, Quresh; Montero, Javier; Moore, Jeffrey; Virgilio Morales Canton,; Morori-Katz, Haia; Morugova, Tatiana; Murakami, Tomoaki; Muzyka-Wozniak, Maria; Nardi, Marco; Nemcansky, Jan; Nester-Ostrowska, Kamila; Neto, Julio; Newell, Charles; Nicolo, Massimo; Nielsen, Jared; Noda, Kousuke; Obana, Akira; Ogata, Nahoko; Hideyasu, Oh; Kean, Oh; Ohr, Matthew; Oleksy, Piotr; Oliver, Scott; Olivier, Sebastien; Osher, James; Ozcalişkan, Sehnaz; Ozturk, Banu; Papp, Andras; Kyu Hyung Park,; D Wilkin Parke,; Maria Cristina Parravano,; Patel, Sugat; Patel, Sunil; Pearce, Ian; Pearlman, Joel; Penha, Fernando; Perente, Irfan; Perkins, Stephen; Pertile, Grazia; Petkova, Iva; Peto, Tunde; Pieramici, Dante; Pollreisz, Andreas; Pongsachareonnont, Pear; Pozdeyeva, Nadezhda; Priglinger, Siegfried; Qureshi, Jawad; Raczynska, Dorota; Rajagopalan, Rajesh; Juan Ramirez Estudillo,; Raskauskas, Paul; Rathod, Rajiv; Razavi, Hessam; Regillo, Carl; Ricci, Federico; Rofagha, Soraya; Romanczak, Dominika; Romanowska-Dixon, Bożena; Rosberger, Daniel; Rosenblatt, Irit; Rosenblatt, Brett; Ross, Adam; Ruamviboonsuk, Paisan; Jose Maria Ruiz Moreno,; Salomão, Gustavo; Sandhu, Sukhpal; Sandner, Dirk; Sararols, Laura; Sawada, Osamu; Schadlu, Ramin; Schlottmann, Patricio; Schuart, Claudia; Seitz, Berthold; Seres, András; Sermet, Figen; Shah, Sandeep; Shah, Ankur; Shah, Rohan; Sharma, Sumit; Sheidow, Thomas; Sheth, Veeral; Shimouchi, Akito; Shimura, Masahiko; Sikorski, Bartosz; Silva, Rufino; Singer, Michael; Singerman, Lawrence; Singh, Rishi; Souied, Eric; David, J Spinak; Spital, Georg; Steinle, Nathan; Stern, Jeffrey; Stoller, Glenn; Stoltz, Robert; Stone, Cameron; Stone, Amy; Suan, Eric; Sugimoto, Masahiko; Sugita, Iichiro; Sun, Jennifer; Sun, Xiaodong; Suner, Ivan; Szalczer, Lajos; Szecsko, Timea; Tabassian, Ali; Tadayoni, Ramin; Takagi, Hitoshi; Takayama, Kei; Taleb, Alexandre; Talks, James; Tan, Gavin; Tanabe, Teruyo; Taylor, Stanford; Thach, Allen; Thompson, John; Tlucek, Paul; Torti, Robert; Daniela Tosheva Guneva,; Toth-Molnar, Edit; Uchiyama, Eduardo; Vajas, Attila; Varma, Deepali; Varsanyi, Balazs; Vassileva, Petja; Vaz-Pereira, Sara; Veith, Miroslav; Jose Ignacio Vela,; Viola, Francesco; Virgili, Gianni; Vogt, Gábor; Vorum, Henrik; Weber, Pamela; Wecke, Thoalf; Wee, Raymond; Weger, Martin; Weishaar, Paul; John, A Wells; Wickremasinghe, Sanjeewa; Thomas Reginald Williams,; Williams, Thomas; Williams, Geoff; Wolf, Armin; Wolfe, Jeremy; Wong, James; Wong, David; Wong, Ian; Wong, Robert; Wowra, Bogumil; Charles, C Wykoff; Wylęgała, Edward; Yang, Chang-Hao; Yasukawa, Tsutomu; Yates, Paul; Yilmaz, Gursel; Yiu, Glenn; Young Hee Yoon,; Yoreh, Barak; Yoshida, Shigeo; Hyeong Gon Yu,; Seung Young Yu,; Yurieva, Tatiana; Zacharias, Leandro; Karolina Zaczek Zakrzewska,; Zambrano, Alberto; Zatorska, Barbara; Zeolite, Carlos; Zheutlin, Jeffrey

doi:10.1016/S0140-6736(22)00018-6

Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials

Charles C Wykoff;Francis Abreu;Anthony P Adamis;Karen Basu;David A Eichenbaum;Zdenka Haskova;Hugh Lin;Anat Loewenstein;Shaun Mohan;Ian A Pearce;Taiji Sakamoto;Patricio G Schlottmann;David Silverman;Jennifer K Sun;John A Wells;Jeffrey R Willis;Ramin Tadayoni;Thomas Aaberg Jr;Ashkan Abbey;Elmira Abdulaeva;Santiago Abengoechea;Prema Abraham;Thomas Ach;Serrhel Adams;Alfredo Adan Civera;Sean Adrean;Hansjurgen Agostini;Suhail Alam;Arturo Alezzandrini;Virgil Alfaro;Daniel Aliseda;Arghavan Almony;Pedro Amat;Payam Amini;Andrew Antoszyk;Luis Arias;Riaz Asaria;Marcos Avila;Carl C Awh;Joaquin Bafalluy;Carl Baker;Francesco Bandello;Mark Barakat;Karen Barraza;Gyorgy Bator;Caroline Baumal;Rubens Belfort Jr;Chris Bergstrom;George Bertolucci;Thomas Bochow;Matthias Bolz;Emilia Borcz;Arnaldo Bordon;David Boyer;Galina Bratko;Michael Brent;Jamin Brown;David M Brown;Maria Budzinskaya;Sylvia Buffet;Stuart Burgess;Ben Burton;Miguel Busquets;Francisco Cabrera;Carlo Cagini;Jorge Calzada;Peter Campochiaro;John Carlson;Alessandro Castellarin;Carlos Cava;Voraporn Chaikitmongkol;Clement Chan;Emmanuel Chang;Jonathan Chang;Andrew Chang;Steve Charles;Nauman Chaudhry;Caroline Chee;Judy Chen;Fred Chen;Shih-Jen Chen;Richard Cheong-Leen;Allen Chiang;Mark Chittum;David Chow;Brian Connolly;Pierre Loic Cornut;Karl Csaky;Carl Danzig;Arup Das;Vesselin Daskalov;Carmen Desco;Amr Dessouki;John Dickinson;Brian Do;Michael Dollin;Pravin Dugel;Jaroslava Dusova;David Eichenbaum;Bora Eldem;Robert Engstrom;Jan Ernest;Joan Josep Escobar;Simona Esposti;Nicole Eter;Naomi Falk;Andrej Farkas;Leonard Feiner;Nicolas Feltgen;Carlos Fernandez;Alvaro Fernandez Vega;Philip Ferrone;Joao Figueira;Marta Figueroa;Oliver Findl;Howard Fine;Jorge Fortun;Gregory M Fox;Scott Foxman;Carsten Framme;Samantha Fraser-Bell;Arthur Fu;Akira Fukutomi;Nicholas Fung;Federico Furno Sola;Roberto Gallego-Pinazo;Renata Garcia;Alfredo Garcia-Layana;Maciej Gawecki;Sheen George;Faruque Ghanchi;Ghassan Ghorayeb;Roger Goldberg;Michaella Goldstein;Nuno Gomes;Francisco Gomez Ulla;Victor Gonzalez;Craig Greven;Sunil Gupta;Miguel Guzman;Martin Harris;Katja Hatz;Vivienne Hau;Vincent Hau;Ken Hayashi;Jeffrey Heier;Ewa Herba;Vrinda Hershberger;Patrick Higgins;Akito Hirakata;Allen Ho;Nancy Holekamp;Shigeru Honda;Jason Hsu;Allen Hu;Maria Hurcikova;Yasuhiro Ikeda;Ricky Isernhagen;Yasuki Ito;Tim Jackson;Rachael Jacoby;Afsar Jafree;Golnaz Javey;Cameron Javid;Chirag Jhaveri;Mark Johnson;Marek Kacerík;Jakub Kaluzny;Daniel Kampik;Se Woong Kang;Kapil Kapoor;Levent Karabas;Tsutomu Kawasaki;Agnes Kerenyi;Arshad Khanani;Rahul Khurana;Brian Kim;Kazuhiro Kimura;Genichiro Kishino;Shigehiko Kitano;Kendra Klein-Mascia;Gregg Kokame;Jean Francois Korobelnik;Alexey Kulikov;Ajay Kuriyan;Henry Kwong;Robert Kwun;Timothy Lai;Chi-Chun Lai;Philip Laird;Laurent Lalonde;Paolo Lanzetta;Michael Larsen;Caroline Laugesen;Daniel Lavinsky;Olivier Lebreton;Seong Lee;Jaime Levy;Blandina Lipkova;Mimi Liu;Judy Liu;Chris P Lohmann;Nikolas London;Katrin Lorenz;Andrew Lotery;David Lozano Rechy;Silvio Lujan;Patrick Ma;Takatoshi Maeno;Sajjad Mahmood;Fuad Makkouk;Khurram Malik;Dennis Marcus;Alan Margherio;Leonardo Mastropasqua;Raj Maturi;Frank McCabe;Martin McKibbin;Hemal Mehta;Geeta Menon;Jale Mentes;Katarzyna Michalska-Malecka;Aneta Misheva;Yoshinori Mitamura;Paul Mitchell;Yasha Modi;Quresh Mohamed;Javier Montero;Jeffrey Moore;Virgilio Morales Canton;Haia Morori-Katz;Tatiana Morugova;Tomoaki Murakami;Maria Muzyka-Wozniak;Marco Nardi;Jan Nemcansky;Kamila Nester-Ostrowska;Julio Neto;Charles Newell;Massimo Nicolo;Jared Nielsen;Kousuke Noda;Akira Obana;Nahoko Ogata;Hideyasu Oh;Kean Oh;Matthew Ohr;Piotr Oleksy;Scott Oliver;Sebastien Olivier;James Osher;Sehnaz Ozcalişkan;Banu Ozturk;Andras Papp;Kyu Hyung Park;D Wilkin Parke;Maria Cristina Parravano;Sugat Patel;Sunil Patel;Ian Pearce;Joel Pearlman;Fernando Penha;Irfan Perente;Stephen Perkins;Grazia Pertile;Iva Petkova;Tunde Peto;Dante Pieramici;Andreas Pollreisz;Pear Pongsachareonnont;Nadezhda Pozdeyeva;Siegfried Priglinger;Jawad Qureshi;Dorota Raczynska;Rajesh Rajagopalan;Juan Ramirez Estudillo;Paul Raskauskas;Rajiv Rathod;Hessam Razavi;Carl Regillo;Federico Ricci;Soraya Rofagha;Dominika Romanczak;Bożena Romanowska-Dixon;Daniel Rosberger;Irit Rosenblatt;Brett Rosenblatt;Adam Ross;Paisan Ruamviboonsuk;Jose Maria Ruiz Moreno;Gustavo Salomão;Sukhpal Sandhu;Dirk Sandner;Laura Sararols;Osamu Sawada;Ramin Schadlu;Patricio Schlottmann;Claudia Schuart;Berthold Seitz;András Seres;Figen Sermet;Sandeep Shah;Ankur Shah;Rohan Shah;Sumit Sharma;Thomas Sheidow;Veeral Sheth;Akito Shimouchi;Masahiko Shimura;Bartosz Sikorski;Rufino Silva;Michael Singer;Lawrence Singerman;Rishi Singh;Eric Souied;David J Spinak;Georg Spital;Nathan Steinle;Jeffrey Stern;Glenn Stoller;Robert Stoltz;Cameron Stone;Amy Stone;Eric Suan;Masahiko Sugimoto;Iichiro Sugita;Jennifer Sun;Xiaodong Sun;Ivan Suner;Lajos Szalczer;Timea Szecsko;Ali Tabassian;Ramin Tadayoni;Hitoshi Takagi;Kei Takayama;Alexandre Taleb;James Talks;Gavin Tan;Teruyo Tanabe;Stanford Taylor;Allen Thach;John Thompson;Paul Tlucek;Robert Torti;Daniela Tosheva Guneva;Edit Toth-Molnar;Eduardo Uchiyama;Attila Vajas;Deepali Varma;Balazs Varsanyi;Petja Vassileva;Sara Vaz-Pereira;Miroslav Veith;Jose Ignacio Vela;Francesco Viola;Gianni Virgili;Gábor Vogt;Henrik Vorum;Pamela Weber;Thoalf Wecke;Raymond Wee;Martin Weger;Paul Weishaar;John A Wells;Sanjeewa Wickremasinghe;Thomas Reginald Williams;Thomas Williams;Geoff Williams;Armin Wolf;Jeremy Wolfe;James Wong;David Wong;Ian Wong;Robert Wong;Bogumil Wowra;Charles C Wykoff;Edward Wylęgała;Chang-Hao Yang;Tsutomu Yasukawa;Paul Yates;Gursel Yilmaz;Glenn Yiu;Young Hee Yoon;Barak Yoreh;Shigeo Yoshida;Hyeong Gon Yu;Seung Young Yu;Tatiana Yurieva;Leandro Zacharias;Karolina Zaczek Zakrzewska;Alberto Zambrano;Barbara Zatorska;Carlos Zeolite;Jeffrey Zheutlin

2022-01-01

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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11567/1094354

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Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials

2022-01-01

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