IRIS
TOMATI, VALERIA
 Distribuzione geografica
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Continente #
EU - Europa 464
Totale 464
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Nazione #
IT - Italia 464
Totale 464
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Città #
Genova 219
Rapallo 122
Genoa 119
Bordighera 4
Totale 464
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Nome #
Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays 84
High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel 67
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel 54
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs 46
The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism 45
Targeting of Ubiquitin E3 Ligase RNF5 as a Novel Therapeutic Strategy in Neuroectodermal Tumors 45
Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays 41
Two CFTR mutations within codon 970 differently impact on the chloride channel functionality 38
Partial rescue of f508del-cftr stability and trafficking defects by double corrector treatment 38
Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background 21
Patient's dermal fibroblasts as disease markers for visceral myopathy 20
Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators 5
Totale 504
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Categoria #
all - tutte 2.920
article - articoli 2.920
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 5.840
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021130 0 0 24 47 0 0 10 7 5 18 17 2
2021/2022120 0 4 1 9 3 5 2 18 10 21 32 15
2022/2023151 11 12 5 13 24 18 4 11 21 2 25 5
2023/2024102 5 11 4 17 8 18 3 7 5 4 8 12
2024/20251 1 0 0 0 0 0 0 0 0 0 0 0
Totale 504