MORETTA, LORENZO

MORETTA, LORENZO  

100008 - Dipartimento di medicina sperimentale  

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2B4 (CD244) is expressed and functional on human eosinophils. 1-gen-2005 Munitz, A; Bachelet, I; Fraenkel, S; Katz, G; Mandelboim, O; Simon, Hu; Moretta, Lorenzo; Colonna, M; AND LEVI SCHAFFER, F.
2B4 functions as a co-receptor in human NK cell activation 1-gen-2000 Sivori, Simona; Moretta, Lorenzo; Falco, M.; Marcenaro, Emanuela; Biassoni, R.; Bottino, Cristina; Moretta, L.; Moretta, Alessandro
4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin. 1-gen-1984 Azzarone, B; Suarez, H; Mingari, MARIA CRISTINA; Moretta, Lorenzo; Fauci, As
A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors 1-gen-2017 Sullivan, Lucy C; Walpole, Nicholas G; Farenc, Carine; Pietra, Gabriella; Sum, Matthew J. Wenhwa; Clements, Craig S; Lee, Eleanor J; Beddoe, Travis; Falco, Michela; Mingari, Maria Cristina; Moretta, Lorenzo; Gras, Stephanie; Rossjohn, Jamie; Brooks, Andrew G.
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s). 1-gen-1988 Ciccone, Ermanno; Ferrini, S; Bottino, Cristina; Viale, O; Prigione, I; Pantaleo, G; Tambussi, G; Moretta, Alessandro; Moretta, Lorenzo
A new mechanism of resistance to NK cell attack in melanoma 1-gen-2012 M., Vitale; M., Balsamo; M., Parodi; Pietra, Gabriella; C., Manzini; Moretta, Alessandro; W., Vermi; F., Facchetti; Moretta, Lorenzo; Mingari, MARIA CRISTINA
A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation 1-gen-2015 Morandi, Fabio; Morandi, Barbara; Horenstein, Alberto L.; Chillemi, Antonella; Quarona, Valeria; Zaccarello, Gianluca; Carrega, Paolo; Ferlazzo, Guido; Mingari, Maria Cristina; Moretta, Lorenzo; Pistoia, Vito; Malavasi, Fabio
A novel 120-kD surface antigen expressed by a subset of human lymphocytes. Evidence that lymphokine-activated killer cells express this molecule and use it in their effector function. 1-gen-1987 Zocchi, Mr; Bottino, Cristina; Ferrini, S; Moretta, Alessandro; Moretta, Lorenzo
A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2 1-gen-2010 Sivori, Simona; Falco, M.; Carlomagno, Simona; Romeo, E.; Soldani, C.; Bensussan, A.; Viola, A.; Moretta, Alessandro; Moretta, Lorenzo
A novel pathway of human B cell activation initiated by CK226 surface antigen. 1-gen-1990 Poggi, A; Maggi, E; Biagiotti, R; Giudizi, Mg; Almerigogna, F; Pella, N; Caligaris Cappio, F; Romagnani, S; Moretta, Lorenzo
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. 1-gen-1990 Moretta, Alessandro; Tambussi, G; Bottino, Cristina; Tripodi, G; Merli, A; Ciccone, Ermanno; Pantaleo, G; Moretta, Lorenzo
A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation. 1-gen-1991 Ferrini, S; Cantoni, Claudia; Ciccone, Ermanno; Biassoni, R; Prigione, I; Bottino, Cristina; Venzano, P; Moretta, Lorenzo
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation. 1-gen-1996 Bottino, Cristina; Sivori, Simona; Vitale, M; Cantoni, Claudia; Falco, M; Pende, D; Morelli, L; Augugliaro, R; Semenzato, G; Biassoni, R; Moretta, Alessandro; Moretta, Lorenzo
A phase I study of recombinant interleukin-2 intraperitoneal infusion in patients with neoplastic ascites: toxic effects and immunologic results. 1-gen-1991 Melioli, G; Sertoli, Mr; Bruzzone, M; Nobile, Mt; Rosso, R; Percivale, Pl; Catturich, A; Badellino, F; Balletto, N; Civalleri, D; Moretta, Lorenzo
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes. 1-gen-2012 Bryceson, Yt; Pende, Daniela; Maul Pavicic, A; Gilmour, Kc; Ufheil, H; Vraetz, T; Chiang, Sc; Marcenaro, S; Meazza, Raffaella; Bondzio, I; Walshe, D; Janka, G; Lehmberg, K; Beutel, K; zur Stadt, U; Binder, N; Arico, M; Moretta, Lorenzo; Henter, Ji; Ehl, S.
A single amino acid change, A91V, leads to conformational changes which can impair processing to the active form of perforin. 1-gen-2005 Trambas, C; Gallo, F; Pende, D; Marcenaro, S; Moretta, Lorenzo; DE FUSCO, C; Notarangelo, L; Arico', M; AND GRIFFITHS, Gm
Activated T lymphocytes in patients with multiple sclerosis. 1-gen-1983 Golaz, J; Steck, A; Moretta, Lorenzo
Activating and inhibitory killer immunoglobulin-like receptors (KIR) in haploidentical haemopoietic stem cell transplantation to cure high-risk leukaemias. 1-gen-2009 Moretta, Alessandro; Pende, D; Locatelli, F; Moretta, Lorenzo
Activating KIRs and NKG2C in viral infections: Toward NK cell memory? 1-gen-2015 DELLA CHIESA, Mariella; Sivori, Simona; Carlomagno, Simona; Moretta, Lorenzo; Moretta, Alessandro
Activating NK cell receptor expression/function (NKp30, NKp46, DNAM-1) during chronic viraemic HCV infection is associated with the outcome of combined treatment. 1-gen-2011 Bozzano, F; Picciotto, Antonino; Costa, P; Marras, Francesco; Fazio, V; Hirsch, I; Olive, D; Moretta, Lorenzo; DE MARIA, Andrea