SPAGGIARI, GRAZIA MARIA
SPAGGIARI, GRAZIA MARIA
100008 - Dipartimento di medicina sperimentale
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112)
2005-01-01 Pende, D.; Spaggiari, GRAZIA MARIA; Marcenaro, S.; Martini, S.; Rivera, P.; Capobianco, A.; Falco, M.; Lanino, E.; Pierri, Ivana; Zambello, R.; Bacigalupo, A.; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo
Cellular and molecular interactions of mesenchymal stem cells in innate immunity.
2013-01-01 Spaggiari, GRAZIA MARIA; Moretta, Lorenzo
Cord Blood-Derived Natural Killer Cell Exploitation in Immunotherapy Protocols: More Than a Promise?
2022-01-01 Damele, Laura; Spaggiari, Grazia Maria; Parodi, Monica; Mingari, Maria Cristina; Vitale, Massimo; Vitale, Chiara
Dendritic cells efficiently cross-prime HLA class I restricted cytolytic T lymphocytes when pulsed with both apoptotic and necrotic cells but not with soluble cell-derived lysates.
2000-01-01 Ferlazzo, G; Semino, C; Spaggiari, GRAZIA MARIA; Meta, M; Mingari, MARIA CRISTINA; Melioli, G.
Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors.
2000-01-01 Ferlazzo, G.; Spaggiari, GRAZIA MARIA; Semino, C.; Melioli, G.; Moretta, Lorenzo
Expression of the DNAM-1 ligands Nectin-2 (CD112) and poliovirus receptor (CD155) on dendritic cells: relevance for natural killer/dendritic cells interaction
2006-01-01 Pende, D; Castriconi, Roberta; Romagnani, P; Spaggiari, GRAZIA MARIA; Marcenaro, S; Dondero, Alessandra; Lazzari, E; Lasagni, L; Martini, S; Rivera, P; Capobianco, A; Moretta, Lorenzo; Moretta, Alessandro; Bottino, Cristina
IFN-gamma production in human NK cells through the engagement of CD8 by soluble or surface HLA class I molecules
2003-01-01 Spaggiari, GRAZIA MARIA; Contini, Paola; Negrini, Simone; Dondero, Alessandra; Carosio, R.; Ghio, M.; Puppo, Francesco; Indiveri, Francesco; Zocchi, M. R.; Poggi, A.
Isolation and characterization of renal cancer stem cells from patient-derived xenografts.
2016-01-01 Hasmim, M; Bruno, S; Azzi, S; Gallerne, C; Michel, Jg; Chiabotto, G; Lecoz, V; Romei, C; Spaggiari, Gm; Pezzolo, A; Pistoia, V; Angevin, E; Gad, S; Ferlicot, S; Messai, Y; Kieda, C; Clay, D; Sabatini, F; Escudier, B; Camussi, G; Eid, P; Azzarone, B; Chouaib, S.
Mesenchymal stem cell-Natural Killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.
2006-01-01 Spaggiari, GRAZIA MARIA; Capobianco, A; Becchetti, S; Mingari, MARIA CRISTINA; Moretta, Lorenzo
Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function.
2011-01-01 Abdelrazik, H; Spaggiari, GRAZIA MARIA; Chiossone, Laura; Moretta, Lorenzo
Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2
2008-01-01 Spaggiari, GRAZIA MARIA; Capobianco, A; Abdelrazik, H; Becchetti, F; Mingari, MARIA CRISTINA; Moretta, Lorenzo
Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses
2016-01-01 Chiossone, Laura; Conte, Romana; Spaggiari, GRAZIA MARIA; Serra, Martina; Romei, Cristina; Bellora, Francesca; Becchetti, Flavio; Andaloro, Antonio; Moretta, Lorenzo; Bottino, Cristina
miR-24-3p down-regulates the expression of the apoptotic factors FasL and BIM in human natural killer cells
2022-01-01 Regis, Stefano; Dondero, Alessandra; Spaggiari, Grazia Maria; Serra, Martina; Caliendo, Fabio; Bottino, Cristina; Castriconi, Roberta
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: Central role of MSC-derived prostaglandin E2
2009-01-01 Spaggiari, GRAZIA MARIA; Abdelrazik, H; Becchetti, F; Moretta, Lorenzo
Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants
2021-01-01 Dondero, A.; Morini, M.; Cangelosi, D.; Mazzocco, K.; Serra, M.; Spaggiari, G. M.; Rotta, G.; Tondo, A.; Locatelli, F.; Castellano, A.; Scuderi, F.; Sementa, A. R.; Eva, A.; Conte, M.; Garaventa, A.; Bottino, C.; Castriconi, R.
NCR + ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures
2015-01-01 Carrega, Paolo; Loiacono, Fabrizio; Di Carlo, Emma; Scaramuccia, Angelo; Mora, Marco; Conte, Romana; Benelli, Roberto; Spaggiari, GRAZIA MARIA; Cantoni, Claudia; Campana, Stefania; Bonaccorsi, Irene; Morandi, Barbara; Truini, Mauro; Mingari, MARIA CRISTINA; Moretta, Lorenzo; Ferlazzo, Guido
Neuroblastoma Tumor-Associated Mesenchymal Stromal Cells Regulate the Cytolytic Functions of NK Cells
2023-01-01 Di Matteo, Sabina; Avanzini, Maria Antonietta; Pelizzo, Gloria; Calcaterra, Valeria; Croce, Stefania; Spaggiari, Grazia Maria; Theuer, Charles; Zuccotti, Gianvincenzo; Moretta, Lorenzo; Pelosi, Andrea; Azzarone, Bruno
NK cell activation by dendritic cells is dependent on LFA-1-mediated induction of calcium-calmodulin kinase II: inhibition by HIV-1 Tat C-terminal domain.
2002-01-01 Poggi, A; Carosio, R; Spaggiari, GRAZIA MARIA; Fortis, C; Tambussi, G; Dellantonio, G; DAL CIN, E; Rubartelli, A; Zocchi, Mr
NK cell-mediated lysis of autologous antigen presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the Natural Cytotoxicity Receptors NKp30 and NKp46
2001-01-01 Spaggiari, GRAZIA MARIA; Carosio, R; Pende, D; Marcenaro, S; Rivera, P; Zocchi, Mr; Moretta, Lorenzo; Poggi, A.
Preterm Cord Blood Contains a Higher Proportion of Immature Hematopoietic Progenitors Compared to Term Samples
2015-01-01 Podestà, Marina; Bruschettini, Matteo; Cossu, Claudia; Sabatini, Federica; Dagnino, Monica; Romantsik, Olga; Spaggiari, GRAZIA MARIA; Ramenghi, LUCA ANTONIO; Frassoni, Francesco
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112) | 1-gen-2005 | Pende, D.; Spaggiari, GRAZIA MARIA; Marcenaro, S.; Martini, S.; Rivera, P.; Capobianco, A.; Falco, M.; Lanino, E.; Pierri, Ivana; Zambello, R.; Bacigalupo, A.; Mingari, MARIA CRISTINA; Moretta, Alessandro; Moretta, Lorenzo | |
| Cellular and molecular interactions of mesenchymal stem cells in innate immunity. | 1-gen-2013 | Spaggiari, GRAZIA MARIA; Moretta, Lorenzo | |
| Cord Blood-Derived Natural Killer Cell Exploitation in Immunotherapy Protocols: More Than a Promise? | 1-gen-2022 | Damele, Laura; Spaggiari, Grazia Maria; Parodi, Monica; Mingari, Maria Cristina; Vitale, Massimo; Vitale, Chiara | |
| Dendritic cells efficiently cross-prime HLA class I restricted cytolytic T lymphocytes when pulsed with both apoptotic and necrotic cells but not with soluble cell-derived lysates. | 1-gen-2000 | Ferlazzo, G; Semino, C; Spaggiari, GRAZIA MARIA; Meta, M; Mingari, MARIA CRISTINA; Melioli, G. | |
| Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors. | 1-gen-2000 | Ferlazzo, G.; Spaggiari, GRAZIA MARIA; Semino, C.; Melioli, G.; Moretta, Lorenzo | |
| Expression of the DNAM-1 ligands Nectin-2 (CD112) and poliovirus receptor (CD155) on dendritic cells: relevance for natural killer/dendritic cells interaction | 1-gen-2006 | Pende, D; Castriconi, Roberta; Romagnani, P; Spaggiari, GRAZIA MARIA; Marcenaro, S; Dondero, Alessandra; Lazzari, E; Lasagni, L; Martini, S; Rivera, P; Capobianco, A; Moretta, Lorenzo; Moretta, Alessandro; Bottino, Cristina | |
| IFN-gamma production in human NK cells through the engagement of CD8 by soluble or surface HLA class I molecules | 1-gen-2003 | Spaggiari, GRAZIA MARIA; Contini, Paola; Negrini, Simone; Dondero, Alessandra; Carosio, R.; Ghio, M.; Puppo, Francesco; Indiveri, Francesco; Zocchi, M. R.; Poggi, A. | |
| Isolation and characterization of renal cancer stem cells from patient-derived xenografts. | 1-gen-2016 | Hasmim, M; Bruno, S; Azzi, S; Gallerne, C; Michel, Jg; Chiabotto, G; Lecoz, V; Romei, C; Spaggiari, Gm; Pezzolo, A; Pistoia, V; Angevin, E; Gad, S; Ferlicot, S; Messai, Y; Kieda, C; Clay, D; Sabatini, F; Escudier, B; Camussi, G; Eid, P; Azzarone, B; Chouaib, S. | |
| Mesenchymal stem cell-Natural Killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. | 1-gen-2006 | Spaggiari, GRAZIA MARIA; Capobianco, A; Becchetti, S; Mingari, MARIA CRISTINA; Moretta, Lorenzo | |
| Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function. | 1-gen-2011 | Abdelrazik, H; Spaggiari, GRAZIA MARIA; Chiossone, Laura; Moretta, Lorenzo | |
| Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2 | 1-gen-2008 | Spaggiari, GRAZIA MARIA; Capobianco, A; Abdelrazik, H; Becchetti, F; Mingari, MARIA CRISTINA; Moretta, Lorenzo | |
| Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses | 1-gen-2016 | Chiossone, Laura; Conte, Romana; Spaggiari, GRAZIA MARIA; Serra, Martina; Romei, Cristina; Bellora, Francesca; Becchetti, Flavio; Andaloro, Antonio; Moretta, Lorenzo; Bottino, Cristina | |
| miR-24-3p down-regulates the expression of the apoptotic factors FasL and BIM in human natural killer cells | 1-gen-2022 | Regis, Stefano; Dondero, Alessandra; Spaggiari, Grazia Maria; Serra, Martina; Caliendo, Fabio; Bottino, Cristina; Castriconi, Roberta | |
| MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: Central role of MSC-derived prostaglandin E2 | 1-gen-2009 | Spaggiari, GRAZIA MARIA; Abdelrazik, H; Becchetti, F; Moretta, Lorenzo | |
| Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants | 1-gen-2021 | Dondero, A.; Morini, M.; Cangelosi, D.; Mazzocco, K.; Serra, M.; Spaggiari, G. M.; Rotta, G.; Tondo, A.; Locatelli, F.; Castellano, A.; Scuderi, F.; Sementa, A. R.; Eva, A.; Conte, M.; Garaventa, A.; Bottino, C.; Castriconi, R. | |
| NCR + ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures | 1-gen-2015 | Carrega, Paolo; Loiacono, Fabrizio; Di Carlo, Emma; Scaramuccia, Angelo; Mora, Marco; Conte, Romana; Benelli, Roberto; Spaggiari, GRAZIA MARIA; Cantoni, Claudia; Campana, Stefania; Bonaccorsi, Irene; Morandi, Barbara; Truini, Mauro; Mingari, MARIA CRISTINA; Moretta, Lorenzo; Ferlazzo, Guido | |
| Neuroblastoma Tumor-Associated Mesenchymal Stromal Cells Regulate the Cytolytic Functions of NK Cells | 1-gen-2023 | Di Matteo, Sabina; Avanzini, Maria Antonietta; Pelizzo, Gloria; Calcaterra, Valeria; Croce, Stefania; Spaggiari, Grazia Maria; Theuer, Charles; Zuccotti, Gianvincenzo; Moretta, Lorenzo; Pelosi, Andrea; Azzarone, Bruno | |
| NK cell activation by dendritic cells is dependent on LFA-1-mediated induction of calcium-calmodulin kinase II: inhibition by HIV-1 Tat C-terminal domain. | 1-gen-2002 | Poggi, A; Carosio, R; Spaggiari, GRAZIA MARIA; Fortis, C; Tambussi, G; Dellantonio, G; DAL CIN, E; Rubartelli, A; Zocchi, Mr | |
| NK cell-mediated lysis of autologous antigen presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the Natural Cytotoxicity Receptors NKp30 and NKp46 | 1-gen-2001 | Spaggiari, GRAZIA MARIA; Carosio, R; Pende, D; Marcenaro, S; Rivera, P; Zocchi, Mr; Moretta, Lorenzo; Poggi, A. | |
| Preterm Cord Blood Contains a Higher Proportion of Immature Hematopoietic Progenitors Compared to Term Samples | 1-gen-2015 | Podestà, Marina; Bruschettini, Matteo; Cossu, Claudia; Sabatini, Federica; Dagnino, Monica; Romantsik, Olga; Spaggiari, GRAZIA MARIA; Ramenghi, LUCA ANTONIO; Frassoni, Francesco |