IRIS
MORETTA, ALESSANDRO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 48.952
Totale 48.952
Salva come PNG Salva come JPEG
Nazione #
IT - Italia 48.952
Totale 48.952
Salva come PNG Salva come JPEG
Città #
Genova 40.047
Rapallo 4.521
Genoa 3.418
Vado Ligure 858
Bordighera 108
Totale 48.952
Salva come PNG Salva come JPEG
Nome #
PVR(CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis 184
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance 178
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function 168
Characterization of CD56-/CD16+ natural killer (NK) cells: A highly dysfunctional NK subset expanded in HIV-infected viremic individuals. 164
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112) 164
NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27 164
NK/DC crosstalk in anti-viral response. 155
Activating KIRs and NKG2C in viral infections: Toward NK cell memory? 153
Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles 151
X-linked lymphoproliferative disease: the dark side of 2B4 function. 149
Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches. 149
New miRNA signature heralds human NK cell subsets at different maturation steps: Involvement of miR-146a-5p in the regulation of KIR expression 149
Antibodies to adhesion molecules inhibit the lytic function of MHC-unrestricted cytotoxic cells by preventing their activation. 147
GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues. 146
B cell growth factor activity of immunoaffinity-purified and recombinant human interleukin 2. 146
Human NK cell receptors/markers: A tool to analyze NK cell development, subsets and function. 145
Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus? 144
Markers and function of human NK cells in normal and pathological conditions 144
Both CD133(+) and CD133(-) medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity 143
Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor 142
Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines 140
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation. 140
Natural killer cells and dendritic cells: rendezvous in abused tissues. 139
Identification of NKp80, a novel triggering molecule expressed by human NK cells. 139
NK cells and their receptors during viral infections. 139
2B4 functions as a co-receptor in human NK cell activation 138
KIR3DS1-Mediated Recognition of HLA-*B51: Modulation of KIR3DS1 Responsiveness by Self HLA-B Allotypes and Effect on NK Cell Licensing 138
Stimulatory receptors in NK and T cells. 136
Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias 136
Bridging innate NK cell Functions with Adaptive Immunity. 135
TLR-stimulated neutrophils instruct NK cells to trigger dendritic cell maturation and promote adaptive T cell responses 135
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. 134
Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor 134
Haploidentical Haematopoietic Stem Cell Transplantation: Role of NK Cells and Effect of Cytomegalovirus Infections 134
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. 134
Multi-directional cross-regulation of NK cell function during innate immune responses. 132
Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice. 130
Expression and crystallographic characterization of the extracellular domain of human Natural Killer cell triggering receptor NKp46 129
Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. 128
Features of Memory-Like and PD-1+ Human NK Cell Subsets 128
Human Natural Killer Cells exposed to IL-2, IL12, IL-18 or IL-4 differently modulate priming of naïve T cells by monocyte-derived Dendritic Cells. 127
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction. 127
Extending killer Ig-like receptor function: from HLA class I recognition to sensors of microbial products 126
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells 126
Isolation of a novel KIR2DL3-specific mAb: comparative analysis of the surface distribution and function of KIR2DL2, KIR2DL3 and KIR2DS2 126
Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses 126
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. 126
Human NK Cells: From Surface Receptors to the Therapy of Leukemias and Solid Tumors. 126
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function. 125
In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors. 125
Surface receptors that regulate the NK cell function: beyond the NK cell scope. 124
Immunobiology of human NK cells. 124
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. 124
Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells 124
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells 123
Pathogen-induced private conversations between natural killer and dendritic cells 123
Innate immunity defects in Hermansky-Pudlak type 2 syndrome 123
Function and specificity of human natural killer cell receptors. 123
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells 123
KIR and KIR ligand polymorphism: a new area for clinical applications? 123
A novel mechanism of antitumor response involving the expansion of CD3+/CD56+ large granular lymphocytes triggered by a tumor-expressed activating ligand. 122
The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors. 122
Clonal heterogeneity in the requirement for T3, T4, and T8 molecules in human cytolytic T lymphocyte function. 122
M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages 122
Alloreactive natural killer cells in targeting high-risk leukaemias. 122
Surface markers of resting and activated human T cells. Functional implications and experimental limits. 121
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis. 121
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NK p30 121
Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response. 121
Dysregulation of regulatory CD56bright NK cells/T cells interactions in multiple sclerosis 121
CD45-mediated regulation of LFA1 function in human natural killer cells. Anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules. 120
Human NK cells: from HLA class I-specific killer Ig-like receptors to the therapy of acute leukemias. 120
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells 120
Human NK receptors: from the molecules to the therapy of high risk leukemias. 120
P49, a putative HLA-G1 specific inhibitory NK receptor belonging to the immunoglobulin Superfamily. 120
IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors 120
Natural killer alloeffector responses in haploidentical hemopoietic stem cell transplantation to treat high-risk leukemias. 119
Human natural killer cells: their origin, receptors and function 119
Unravelling natural killer cell function: triggering and inhibitory human NK receptors. 119
IL-2-mediated T cell proliferation in humans is blocked by a monoclonal antibody directed against monomorphic determinants of HLA-DR antigens. 119
Frequent coexpression of cytolytic activity and lymphokine production among human T lymphocytes. Production of B cell growth factor and interleukin 2 by T8+ and T4+ cytolytic clones. 119
DNAM-1 and PVR regulate monocyte migration through endothelial junctions 119
Receptors for immunoglobulins on resting and activated human T cells. 119
Susceptibility of human melanoma cells to autologous natural killer (NK) cell killing: HLA-related effector mechanisms and role of unlicensed NK cells 119
Subpopulations of human NK (CD3-CD16+) lymphocytes identified by monoclonal antibodies directed to clonally distributed functional surface molecules. 118
Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen-receptor complex. 118
Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals. 117
Learning how to discriminate between friends and enemies,a lesson from Natural Killer cells 117
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s). 117
Regulation of inhibitory and activating killer-cell Ig-like receptor expression occurs in T cells after termination of TCR rearrangements. 117
Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture. 117
NK cells infiltrating a MHC class I-deficient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered NK cell-triggering receptors. 117
Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain. 117
Late development of FcεRγneg adaptive natural killer cells upon human cytomegalovirus reactivation in umbilical cord blood transplantation recipients 117
Human breast tumor cells induce self-tolerance mechanisms to avoid NKG2D-mediated and DNAM-mediated NK cell recognition. 117
Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1. 116
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity. 116
The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes. 116
Entropically assisted carbohydrate recognition by a natural killer cell-surface receptor. 116
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. 116
Totale 13.033
Salva come PNG Salva come JPEG
Categoria #
all - tutte 128.897
article - articoli 115.529
book - libri 0
conference - conferenze 4.822
curatela - curatele 0
other - altro 0
patent - brevetti 7.048
selected - selezionate 0
volume - volumi 1.498
Totale 257.794
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202012.921 0 0 620 876 1.288 1.363 2.196 915 1.258 2.417 1.441 547
2020/20213.315 195 312 275 252 185 377 141 295 351 370 268 294
2021/20226.108 179 498 640 659 277 297 379 1.421 220 550 259 729
2022/20235.521 631 317 52 576 895 1.118 2 397 1.014 34 410 75
2023/20242.479 123 419 69 287 229 353 107 163 194 77 145 313
2024/2025904 126 644 134 0 0 0 0 0 0 0 0 0
Totale 49.512