TONELLI, MICHELE
TONELLI, MICHELE
100006 - Dipartimento di Farmacia
3-(4-Chlorophenyldiazenyl)-1-methyl-1,4,5,6-tetrahydropyridine,
2008-01-01 Fiorella, Meneghetti; Gabriella, Bombieri; Tonelli, Michele
9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp)
2018-01-01 Loddo, Roberta; Francesconi, Valeria; Laurini, Erik; Boccardo, Silvia; Aulic, Suzana; Fermeglia, Maurizio; Pricl, Sabrina; Tonelli, Michele
Acridine derivatives as anti-BVDV agents
2011-01-01 Tonelli, Michele; Vettoretti, G; Tasso, Bruno; Novelli, Federica; Boido, Vito; Sparatore, Fabio; Busonera, B; Ouhtit, A; Farci, P; Blois, S; Giliberti, G; La Colla, P.
Anti-α-glucosidase and antiglycation activities of α-mangostin and new xanthenone derivatives: Enzymatic kinetics and mechanistic insights through in vitro studies
2022-01-01 Djeujo, F. M.; Francesconi, V.; Gonella, M.; Ragazzi, E.; Tonelli, M.; Froldi, G.
Antimicrobial and cytotoxic arylazoenamines. Part III: Antiviral activity of selected classes of arylazoenamines
2008-01-01 Tonelli, Michele; Boido, Vito; Canu, Caterina; Anna, Sparatore; Sparatore, Fabio; Maria Silvia, Paneni; Maurizio, Fermeglia; Sabrina, Pricl; Paolo La, Colla; Laura, Casula; Cristina, Ibba; David, Collu; Roberta, Loddo
Antitarget, Anti-SARS-CoV‑2 Leads, Drugs, and the Drug Discovery−Genetics Alliance Perspective
2023-01-01 Pozzi, Cecilia; Vanet, Anne; Francesconi, Valeria; Tagliazucchi, Lorenzo; Tassone, Giusy; Venturelli, Alberto; Spyrakis, Francesca; Mazzorana, Marco; Paola Costi, Maria; Tonelli, Michele
Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines
2014-01-01 Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Anna, Sparatore; Boido, Vito; Sparatore, Fabio; Sara, Cannas; Paola, Molicotti; Stefania, Zanetti; Silvia, Parapini; Roberta, Loddo
Antiviral Activity of Benzimidazole Derivatives. I. Antiviral Activity of 1-Substituted-2-[(Benzotriazol-1/2-yl)methyl]benzimidazoles.
2008-01-01 Tonelli, Michele; Giuseppe, Paglietti; Boido, Vito; Sparatore, Fabio; Fabio, Marongiu; Esther, Marongiu; Paolo La, Colla; Roberta, Loddo
Antiviral activity of benzimidazole derivatives. II Antiviral activity of 2-phenylbenzimidazole derivatives.
2010-01-01 Tonelli, Michele; Simone, M; Tasso, Bruno; Novelli, Federica; Boido, Vito; Sparatore, Fabio; Paglietti, G; Pricl, S; Gilberti, G; Blois, S; Ibba, C; Sanna, G; Loddo, R; LA COLLA, P.
Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents
2014-01-01 Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Vazzana, Iana; Sparatore, Anna; Boido, Vito; Sparatore, Fabio; La Colla, Paolo; Sanna, Giuseppina; Giliberti, Gabriele; Busonera, Bernardetta; Farci, Pamela; Ibba, Cristina; Loddo, Roberta
Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5
2015-01-01 Roberta, Loddo; Novelli, Federica; Anna, Sparatore; Tasso, Bruno; Tonelli, Michele; Boido, Vito; Sparatore, Fabio; Gabriella, Collu; Ilenia, Delogu; Gabriele, Giliberti; Paolo, La Colla
Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives
2009-01-01 Tonelli, Michele; Vazzana, Iana; Tasso, Bruno; Boido, Vito; Sparatore, Fabio; Fermeglia, M.; Paneni, M. S.; Posocco, P.; Pricl, S.; LA COLLA, P.; Ibba, C.; Secci, B.; Collu, G.; Loddo, R.
Benzimidazole derivatives endowed with potent antileishmanial activity
2018-01-01 Tonelli, Michele; Gabriele, Elena; Piazza, Francesca; Basilico, Nicoletta; Parapini, Silvia; Tasso, Bruno; Loddo, Roberta; Sparatore, Fabio; Sparatore, Anna
Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles
2017-01-01 Cichero, Elena; Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Delogu, I; Loddo, R.; Bruno, Olga; Fossa, Paola
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells
2016-01-01 Villa, Valentina; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Novelli, Federica; Tasso, Bruno; Colucci D’Amato, L.; Gatta, Elena; Tonelli, Michele; Florio, Tullio
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives
2022-01-01 Barbieri, Federica; Bosio, Alessia Graziana; Pattarozzi, Alessandra; Tonelli, Michele; Bajetto, Adriana; Verduci, Ivan; Cianci, Francesca; Cannavale, Gaetano; Palloni, Luca M G; Francesconi, Valeria; Thellung, Stefano; Fiaschi, Pietro; Mazzetti, Samanta; Schenone, Silvia; Balboni, Beatrice; Girotto, Stefania; Malatesta, Paolo; Daga, Antonio; Zona, Gianluigi; Mazzanti, Michele; Florio, Tullio
Clofazimine analogs with antileishmanial and antiplasmodial activity
2015-01-01 Barteselli, A.; Casagrande, M.; Basilico, N.; Parapini, S.; Rusconi, C. M.; Tonelli, Michele; Boido, Vito; Taramelli, D.; Sparatore, Fabio; Sparatore, A.
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling
2024-01-01 Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S.
Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays
2023-01-01 Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity
2011-01-01 Villa, Valentina; Tonelli, Michele; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Tasso, Bruno; Novelli, Federica; Canu, Caterina; Pino, Albiana; Chiovitti, K.; Paludi, D.; Russo, C.; Sparatore, A.; Aceto, A.; Boido, Vito; Sparatore, Fabio; Florio, Tullio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3-(4-Chlorophenyldiazenyl)-1-methyl-1,4,5,6-tetrahydropyridine, | 1-gen-2008 | Fiorella, Meneghetti; Gabriella, Bombieri; Tonelli, Michele | |
| 9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp) | 1-gen-2018 | Loddo, Roberta; Francesconi, Valeria; Laurini, Erik; Boccardo, Silvia; Aulic, Suzana; Fermeglia, Maurizio; Pricl, Sabrina; Tonelli, Michele | |
| Acridine derivatives as anti-BVDV agents | 1-gen-2011 | Tonelli, Michele; Vettoretti, G; Tasso, Bruno; Novelli, Federica; Boido, Vito; Sparatore, Fabio; Busonera, B; Ouhtit, A; Farci, P; Blois, S; Giliberti, G; La Colla, P. | |
| Anti-α-glucosidase and antiglycation activities of α-mangostin and new xanthenone derivatives: Enzymatic kinetics and mechanistic insights through in vitro studies | 1-gen-2022 | Djeujo, F. M.; Francesconi, V.; Gonella, M.; Ragazzi, E.; Tonelli, M.; Froldi, G. | |
| Antimicrobial and cytotoxic arylazoenamines. Part III: Antiviral activity of selected classes of arylazoenamines | 1-gen-2008 | Tonelli, Michele; Boido, Vito; Canu, Caterina; Anna, Sparatore; Sparatore, Fabio; Maria Silvia, Paneni; Maurizio, Fermeglia; Sabrina, Pricl; Paolo La, Colla; Laura, Casula; Cristina, Ibba; David, Collu; Roberta, Loddo | |
| Antitarget, Anti-SARS-CoV‑2 Leads, Drugs, and the Drug Discovery−Genetics Alliance Perspective | 1-gen-2023 | Pozzi, Cecilia; Vanet, Anne; Francesconi, Valeria; Tagliazucchi, Lorenzo; Tassone, Giusy; Venturelli, Alberto; Spyrakis, Francesca; Mazzorana, Marco; Paola Costi, Maria; Tonelli, Michele | |
| Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines | 1-gen-2014 | Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Anna, Sparatore; Boido, Vito; Sparatore, Fabio; Sara, Cannas; Paola, Molicotti; Stefania, Zanetti; Silvia, Parapini; Roberta, Loddo | |
| Antiviral Activity of Benzimidazole Derivatives. I. Antiviral Activity of 1-Substituted-2-[(Benzotriazol-1/2-yl)methyl]benzimidazoles. | 1-gen-2008 | Tonelli, Michele; Giuseppe, Paglietti; Boido, Vito; Sparatore, Fabio; Fabio, Marongiu; Esther, Marongiu; Paolo La, Colla; Roberta, Loddo | |
| Antiviral activity of benzimidazole derivatives. II Antiviral activity of 2-phenylbenzimidazole derivatives. | 1-gen-2010 | Tonelli, Michele; Simone, M; Tasso, Bruno; Novelli, Federica; Boido, Vito; Sparatore, Fabio; Paglietti, G; Pricl, S; Gilberti, G; Blois, S; Ibba, C; Sanna, G; Loddo, R; LA COLLA, P. | |
| Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents | 1-gen-2014 | Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Vazzana, Iana; Sparatore, Anna; Boido, Vito; Sparatore, Fabio; La Colla, Paolo; Sanna, Giuseppina; Giliberti, Gabriele; Busonera, Bernardetta; Farci, Pamela; Ibba, Cristina; Loddo, Roberta | |
| Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5 | 1-gen-2015 | Roberta, Loddo; Novelli, Federica; Anna, Sparatore; Tasso, Bruno; Tonelli, Michele; Boido, Vito; Sparatore, Fabio; Gabriella, Collu; Ilenia, Delogu; Gabriele, Giliberti; Paolo, La Colla | |
| Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives | 1-gen-2009 | Tonelli, Michele; Vazzana, Iana; Tasso, Bruno; Boido, Vito; Sparatore, Fabio; Fermeglia, M.; Paneni, M. S.; Posocco, P.; Pricl, S.; LA COLLA, P.; Ibba, C.; Secci, B.; Collu, G.; Loddo, R. | |
| Benzimidazole derivatives endowed with potent antileishmanial activity | 1-gen-2018 | Tonelli, Michele; Gabriele, Elena; Piazza, Francesca; Basilico, Nicoletta; Parapini, Silvia; Tasso, Bruno; Loddo, Roberta; Sparatore, Fabio; Sparatore, Anna | |
| Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles | 1-gen-2017 | Cichero, Elena; Tonelli, Michele; Novelli, Federica; Tasso, Bruno; Delogu, I; Loddo, R.; Bruno, Olga; Fossa, Paola | |
| Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells | 1-gen-2016 | Villa, Valentina; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Novelli, Federica; Tasso, Bruno; Colucci D’Amato, L.; Gatta, Elena; Tonelli, Michele; Florio, Tullio | |
| Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives | 1-gen-2022 | Barbieri, Federica; Bosio, Alessia Graziana; Pattarozzi, Alessandra; Tonelli, Michele; Bajetto, Adriana; Verduci, Ivan; Cianci, Francesca; Cannavale, Gaetano; Palloni, Luca M G; Francesconi, Valeria; Thellung, Stefano; Fiaschi, Pietro; Mazzetti, Samanta; Schenone, Silvia; Balboni, Beatrice; Girotto, Stefania; Malatesta, Paolo; Daga, Antonio; Zona, Gianluigi; Mazzanti, Michele; Florio, Tullio | |
| Clofazimine analogs with antileishmanial and antiplasmodial activity | 1-gen-2015 | Barteselli, A.; Casagrande, M.; Basilico, N.; Parapini, S.; Rusconi, C. M.; Tonelli, Michele; Boido, Vito; Taramelli, D.; Sparatore, Fabio; Sparatore, A. | |
| Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling | 1-gen-2024 | Grossi, G.; Scarano, N.; Musumeci, F.; Tonelli, M.; Kanov, E.; Carbone, A.; Fossa, P.; Gainetdinov, R. R.; Cichero, E.; Schenone, S. | |
| Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays | 1-gen-2023 | Cichero, Elena; Francesconi, Valeria; Casini, Beatrice; Casale, Monica; Kanov, Evgeny; Gerasimov, Andrey S.; Sukhanov, Ilya; Savchenko, Artem; Espinoza, Stefano; Gainetdinov, Raul R.; Tonelli, Michele | |
| Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity | 1-gen-2011 | Villa, Valentina; Tonelli, Michele; THELLUNG DE COURTELARY, Stefano; Corsaro, Alessandro; Tasso, Bruno; Novelli, Federica; Canu, Caterina; Pino, Albiana; Chiovitti, K.; Paludi, D.; Russo, C.; Sparatore, A.; Aceto, A.; Boido, Vito; Sparatore, Fabio; Florio, Tullio |