IRIS
MOSTI, LUISA
 Distribuzione geografica
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Continente #
EU - Europa 6.754
Totale 6.754
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Nazione #
IT - Italia 6.754
Totale 6.754
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Città #
Genova 5.535
Rapallo 602
Genoa 490
Vado Ligure 120
Bordighera 7
Totale 6.754
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Nome #
An efficient synthesis of functionalized 2-pyridones by direct route or via amide/enolate ammonium salt intermediates 155
1-Phenyl-1H-Indazole derivatives with analgesic and anti-inflammatory activities. 137
Chemometric study and validation strategies in the structure-activity relationships of new cardiotonic agents 133
4-Dialkylamino-1-(5-substituted or unsubstituted 1-phenyl-1H-pyrazol-4-yl)butan-1-ols: synthesis and evaluation of analgesic, anti-inflammatory and platelet anti-aggregating activities 126
Synthesis of 5-substituted 1-aryl-1H-pyrazole-4-acetonitriles, 4-methyl-1-phenyl-1H-pyrazole-3-carbonitrile and pharmacologically active 1-aryl-1H-pyrazole-4-acetic acids. 123
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors 122
3-Acetyl-5-acylpyridin-2(1H)-ones and 3-acetyl-7,8-dihydro-2,5(1H,6H)-quinolinediones: synthesis, cardiotonic activity and computational studies 122
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists. 116
Structural basis for selective PDE 3 inhibition: a docking study 116
Synthesis and Cardiotonic Activity of Novel Pyrimidine Derivatives. Crystallographic and Quantum Chemical Studies 116
Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating actions 115
Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant 114
Exploring the QSAR of pyrazolo[3,4-b]pyridine, pyrazolo[3,4-b]pyridone and pyrazolo[3,4-b]pyrimidine derivatives as antagonists for A1 adenosine receptor. 111
Affinity prediction on A1 adenosine receptor agonists: the chemometric approach 111
Ionization Behaviour and Tautomerism-Dependent Lipophilicity of Pyridine-2(1H)-one Cardiotonic Agents 110
Synthesis, molecular modeling studies and pharmacological activity of selective A1 receptor antagonists 108
DNA-psoralens molecular recognition using molecular dynamics 108
Synthesis and preliminary biological evaluation of novel N-substituted 1-amino-3-[1-methyl(phenyl)-1H-indazol-4-yloxy]-propan-2-ols interesting as potential antiarrhythmic, local anaesthetic and analgesic agents 108
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and QSAR analysis 106
CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists 103
Unprecedented one-pot stereoselective synthesis of Knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents 102
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line 102
Zups: the evolution of a new class of molecular descriptors 100
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1-H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation 100
Insights into Structure-Activity Relationships from Lipophilicity Profiles of Pyridin-2(1H)-one Analogs of the Cardiotonic Agent Milrinone 99
An updated topographical model for phosphodiesterase 4 (PDE4) catalytic site 99
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. 99
Synthesis and Pharmacological Characterization of Functionalized 2-Pyridones Structurally Related to the Cardiotonic Agent Milrinone 98
A chemometric approach to predict A1 agonist effect of adenosine analogues 97
Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses 97
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site 96
2- substituted 5-acetyl-1,6-dihydro-6-oxo-3-pyridinecarboxylates: synthesis and cardiotonic activity 94
Quinolinedione nucleus as a novel scaffold for A1 and A2A adenosine receptor antagonists. 94
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation 94
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking-based CoMFA and CoMSIA analyses 93
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation 93
Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells 92
4-Substituted 1-methyl-1H-indazoles with analgesic, antiinflammatory and antipyretic activities 92
Structure-based Design, Parallel Synthesis, SAR and Molecular Modelling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea (PETT) Derivatives. 91
Towards the identification of the cardiac cAMP phosphodiesterase receptor site 90
Synthesis and biological evaluation of azole derivatives, analogues of bifonazole, with a phenylisoxazolyl or phenylpyrimidinyl moiety 90
4-Substituted 1,5-diarylpyrazoles, analogues of celecoxib: synthesis and preliminary evaluation of biological properties 89
Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies 88
Development of a new topographical model for myocardial cGI-PDE catalytic site 86
Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands 86
A New Milrinone analog: Role of Binding to A1 Adenosine Receptor in its Positive Inotropic Effect on Isolated Guinea Pig and Rat Atria 86
Exploring the molecular basis of selectivity in A1 adenosine receptors antagonist: a case study 86
New halogenated 4-aminopyrazolo[3,4-b]pyridines A1 adenosine receptor ligands 83
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines 83
New milrinone analogues:in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine and inhibition of cardiac type III phosphodiesterase 83
Molecular Modeling of DNA-psoralens complexes 81
Toward the identification of the cardiac cGMP inhibited-phosphodiesterase catalytic site 78
QSAR study on new cardiotonic agents related to milrinone 77
Synthesis of pyrazolo[3,4-d]pyridines selective antagonists of A1 adenosine receptors 77
New pyrazolo[3,4-b]pyridones as selective A1 adenosine receptor antagonists: synthesis, biological evaluation and molecular modeling studies 76
Synthesis, Biological Evaluation and Molecular Modeling Studies on Benzothiadiazine Derivatives as PDE4 Selective Inhibitors 72
Synthesis of indole imminun salts as key-intermediates in a convergent multi-step one-pot stereoselective synthesis of new potent antiproliferative Knoevenagel-type agent 67
Reaction of Sulfene with Heterocyclic N, N-Disubstituted alfa-Amino methyleneketones. IX. Synthesis of 1,2-Oxathiino [6,5-e] indole Derivatives. 66
2-Pyridone derivatives as inotropic agents: synthesis, pharmacology and molecular modeling study 65
Synthesis, antimicrobial activity and molecular modelling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles 64
2-Pyridone derivatives as inotropic agents: synthesis, pharmacology and molecular modeling study 64
New pyrazolo[3,4-b]pyridines antagonist of A1 adenosine receptors 63
omega-Dialkylaminoalkil Ethers of Phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with Analgesic and Anti-inflammatory Activity 62
Reaction of Sulfene with Heterocyclic N,N-Disubstituted alfa-Amino methyleneketones.XI. Synthesis of 1,2-Oxathiino[5,6-d]-1-benzoxepin Derivatives. 61
Androstane derivatives: synthesis of substituted 6'-H-androst-2-eno*3,2-b*pyran-6'-ones. 60
Inotropic Agents. Synthesis and Structure-Activity Relationships of New Milrinone Related cAMP PDEIII inhibitors 60
Modulazioni Strutturali in O-[2-(N-Ftalimmido)etil] Acil(Aril)Tiocarbammati, Inibitori Non-Nucleosidici della Transcrittasi Inversa di HIV-1 58
Glycoside und Depside aus den Blättern von Castanea sativa Mill. 58
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and 3D-QSAR analysis 57
Riconoscimento molecolare DNA-psoraleni mediante tecniche di dinamica molecolare 57
Zupan's descriptors in QSAR applied to the study of a new class of cardiotonic agents 57
In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues 56
Studio computazionale di complessi di intercalazione al buio DNA-psoraleni Pavia, 27-29 maggio 1999 54
Synthesis of new pyrazolo[3,4-b]pyridines: new selective A1 adenosine receptor antagonists 53
Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors 52
Flavonoidverbindungen und Allantoin aus Anchusa officinalis L. 50
Synthesis and photobiological properties of 3-acylangelicins, 3-alkoxycarbonyl-angelicins and related derivatives 47
Totale 6.834
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Categoria #
all - tutte 18.793
article - articoli 15.736
book - libri 0
conference - conferenze 3.057
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.586
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.756 0 0 101 89 171 188 281 98 150 327 265 86
2020/2021349 13 39 16 26 42 22 17 30 37 38 26 43
2021/2022949 43 85 70 91 26 43 63 254 39 85 45 105
2022/2023730 66 47 7 85 122 121 0 37 104 5 117 19
2023/2024361 20 59 11 51 38 51 20 15 9 12 35 40
2024/2025128 24 91 13 0 0 0 0 0 0 0 0 0
Totale 6.834