IRIS
MENOZZI, GIULIA
 Distribuzione geografica
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Continente #
EU - Europa 4.178
Totale 4.178
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Nazione #
IT - Italia 4.178
Totale 4.178
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Città #
Genova 3.544
Rapallo 387
Genoa 246
Bordighera 1
Totale 4.178
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Nome #
Ligand-based homology modelling of the human CB2 receptor SR144528 antagonist binding site: a computational approach to explore the 1,5-diaryl pyrazole scaffold 158
An efficient synthesis of functionalized 2-pyridones by direct route or via amide/enolate ammonium salt intermediates 150
4-Dialkylamino-1-(5-substituted or unsubstituted 1-phenyl-1H-pyrazol-4-yl)butan-1-ols: synthesis and evaluation of analgesic, anti-inflammatory and platelet anti-aggregating activities 122
Synthesis of 5-substituted 1-aryl-1H-pyrazole-4-acetonitriles, 4-methyl-1-phenyl-1H-pyrazole-3-carbonitrile and pharmacologically active 1-aryl-1H-pyrazole-4-acetic acids. 120
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors 118
3-Acetyl-5-acylpyridin-2(1H)-ones and 3-acetyl-7,8-dihydro-2,5(1H,6H)-quinolinediones: synthesis, cardiotonic activity and computational studies 118
Structural basis for selective PDE 3 inhibition: a docking study 115
Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating actions 113
Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant 111
Exploring the QSAR of pyrazolo[3,4-b]pyridine, pyrazolo[3,4-b]pyridone and pyrazolo[3,4-b]pyrimidine derivatives as antagonists for A1 adenosine receptor. 109
Synthesis, molecular modeling studies and pharmacological activity of selective A1 receptor antagonists 107
Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles. X. Synthesis of 5-Substituted Ethyl or Methyl 4-Isoxazolecarboxylates and Methyl 4-(2,2-Dimethyl-1-oxopropyl)-5-isoxazolecarboxylate 107
Synthesis and preliminary biological evaluation of novel N-substituted 1-amino-3-[1-methyl(phenyl)-1H-indazol-4-yloxy]-propan-2-ols interesting as potential antiarrhythmic, local anaesthetic and analgesic agents 107
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and QSAR analysis 102
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1-H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation 98
Unprecedented one-pot stereoselective synthesis of Knoevenagel-type derivatives via in situ condensation of N-methyleniminium salts of ethylenethiourea and ethyleneurea with active methylene reagents 98
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line 98
Synthesis and biological evaluation of [α-(1,5-disubstituted 1H-pyrazol-4-yl)benzyl]azoles, analogues of bifonazole 97
An updated topographical model for phosphodiesterase 4 (PDE4) catalytic site 97
Synthesis and Pharmacological Characterization of Functionalized 2-Pyridones Structurally Related to the Cardiotonic Agent Milrinone 96
Quinolinedione nucleus as a novel scaffold for A1 and A2A adenosine receptor antagonists. 93
New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation 92
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation 92
Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells 91
Towards the identification of the cardiac cAMP phosphodiesterase receptor site 89
Synthesis and biological evaluation of azole derivatives, analogues of bifonazole, with a phenylisoxazolyl or phenylpyrimidinyl moiety 89
Structure-based Design, Parallel Synthesis, SAR and Molecular Modelling Studies of Thiocarbamates, New Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Isosteres of Phenethylthiazolylthiourea (PETT) Derivatives. 88
4-Substituted 1-methyl-1H-indazoles with analgesic, antiinflammatory and antipyretic activities 87
Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies 87
2- substituted 5-acetyl-1,6-dihydro-6-oxo-3-pyridinecarboxylates: synthesis and cardiotonic activity 86
5-Substituted 4-Isoxazolecarboxamides with platelet antiaggregating and other activities 86
Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands 85
Exploring the molecular basis of selectivity in A1 adenosine receptors antagonist: a case study 85
4-Substituted 1,5-diarylpyrazoles, analogues of celecoxib: synthesis and preliminary evaluation of biological properties 84
5-Substituted 4-Isoxazoleacetic acids with analgesic activity. 82
New halogenated 4-aminopyrazolo[3,4-b]pyridines A1 adenosine receptor ligands 81
New pyrazolo[3,4-b]pyridones as selective A1 adenosine receptor antagonists: synthesis, biological evaluation and molecular modeling studies 75
Synthesis of pyrazolo[3,4-d]pyridines selective antagonists of A1 adenosine receptors 75
Reaction of Sulfene with Heterocyclic N, N-Disubstituted alfa-Amino methyleneketones. IX. Synthesis of 1,2-Oxathiino [6,5-e] indole Derivatives. 65
omega-Dialkylaminoalkil Ethers of Phenyl-(5-substituted 1-phenyl-1H-pyrazol-4-yl)methanols with Analgesic and Anti-inflammatory Activity 61
Synthesis, antimicrobial activity and molecular modelling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles 60
Reaction of Sulfene with Heterocyclic N,N-Disubstituted alfa-Amino methyleneketones.XI. Synthesis of 1,2-Oxathiino[5,6-d]-1-benzoxepin Derivatives. 59
Modulazioni Strutturali in O-[2-(N-Ftalimmido)etil] Acil(Aril)Tiocarbammati, Inibitori Non-Nucleosidici della Transcrittasi Inversa di HIV-1 55
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and 3D-QSAR analysis 55
In silico rationalization of the structural and physicochemical requirements for photobiological activity in angelicine derivatives and their heteroanalogues 55
Synthesis and photobiological properties of 3-acylangelicins, 3-alkoxycarbonyl-angelicins and related derivatives 45
Totale 4.243
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Categoria #
all - tutte 10.411
article - articoli 9.597
book - libri 0
conference - conferenze 814
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.822
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019176 0 0 0 0 0 0 0 0 0 0 98 78
2019/20201.190 34 30 65 59 113 133 180 73 100 199 151 53
2020/2021250 12 33 12 17 33 15 18 20 26 25 16 23
2021/2022582 34 54 51 49 11 29 42 141 24 51 30 66
2022/2023463 36 37 3 47 81 75 0 21 60 4 90 9
2023/2024171 8 35 5 39 23 32 12 5 3 9 0 0
Totale 4.243