IRIS
ONOFRI, FRANCO
 Distribuzione geografica
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Continente #
EU - Europa 6.642
Totale 6.642
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Nazione #
IT - Italia 6.642
Totale 6.642
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Città #
Genova 4.906
Rapallo 694
Genoa 654
Vado Ligure 374
Bordighera 14
Totale 6.642
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Nome #
Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements. 169
The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK. 151
Altered mechanisms underlying the abnormal glutamate release in amyotrophic lateral sclerosis at a pre-symptomatic stage of the disease 143
Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites 139
Altered Mechanisms Underlying the Abnormal Glutamate Release in Amyotrophic Lateral Sclerosis at a Pre-Symptomatic Stage of the Disease. 133
Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice 129
PRRT2 Is a Key Component of the Ca2+-Dependent Neurotransmitter Release Machinery 128
Intracellular injection of synapsin I induces neurotransmitter release in C1 neurons of Helix pomatia contacting a wrong target 125
S100A1 codistributes with synapsin I in discrete brain areas and inhibits the F-actin-bundling activity of synapsin I 125
Anti-synapsin monoclonal antibodies: epitope mapping and inhibitory effects on phosphorylation and Grb2 binding. 123
Phosphorylation-dependent effects of synapsin IIa on actin polymerization and network formation 122
Functional role of ATP binding to synapsin I in synaptic vesicle trafficking and release dynamics. 121
Biochemical and functional characterization of the synaptic vesicle-associated form of Ca2+/calmodulin-dependent protein kinase II. 119
Specificity of the binding of synapsin I to Src homology-3 domains 119
Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis 116
Phosphorylation of Synapsin I by Cyclin-Dependent Kinase-5 Sets the Ratio between the Resting and Recycling Pools of Synaptic Vesicles at Hippocampal Synapses 115
Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I. 113
Effects of striatal ischemia induced by endothelin-1 on synaptosomal peroxidative damage and membrane properties 112
Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles. 110
Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity. 109
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex 109
Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment 108
Interactions of synapsin I with phospholipids: possible role in synaptic vesicle clustering and in the maintenance of bilayer structures. 107
Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis. 107
Synapsin associates with cyclophilin B in an ATP- and cyclosporin A-dependent manner 106
The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions. 106
A Novel Topology of Proline-rich Transmembrane Protein 2 (PRRT2): HINTS FOR AN INTRACELLULAR FUNCTION AT THE SYNAPSE 103
Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain. 103
Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases. 101
Intravenous mesenchymal stem cells improve survival and motor functions in symptomatic mutant SOD1/G93A mice 101
Abnormal and precocious exocytotic glutamate release in a mouse model of amyotrophic lateral sclerosis 99
Protein-protein interactions and protein modules in the control of neurotransmitter release 99
Synapsin phosphorylation by SRC tyrosine kinase enhances SRC activity in synaptic vesicles 97
Synaptic mechanisms underlying the excessive and precocious glutamate release in the spinal cord of sod1g93a mice. 97
Intersectin associates with synapsin and regulates its nanoscale localization and function. 95
Interleukin-6 inhibits neurotransmitter release and the spread of excitation in the rat cerebral cortex 94
Synapsin I Senses Membrane Curvature by an Amphipathic Lipid Packing Sensor Motif. 94
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate 93
ERK activation in axonal varicosities modulates presynaptic plasticity in the CA3 region of the hippocampus through synapsin I. 89
Abnormal glutamate release in a mouse model of amyotrophic lateral sclerosis 87
Responses of neostriatal dopaminoceptive cells to the ischemic insult 86
Synapsins Are Downstream Players of the BDNF-Mediated Axonal Growth 86
A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation 86
Abnormal glutamate release in a mouse model of amyotrophic lateral sclerosis 84
GLUTAMATE NEUROTRANSMISSION IS MODIFIED IN THE SOD1/G93A MOUSE MODEL OF ALS 83
Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin 83
Tyrosine phosphorylation of synapsin I by Src regulates synaptic-vesicle trafficking 80
Influence of synapsin I on synaptic vesicles: an analysis by force-volume-mode of the atomic force microscope and dynamic light scattering 77
Synapsin-like molecules in Aplysia Punctata and Helix Pomatia: identification and distribution in the nervous system and during the formation of synaptic contacts in vitro. 75
G93A mutated SOD1-linked murine ALS produces abnormal exocytotic release of glutamate 75
PHOSPHORYLATION OF SYNAPSIN I BY CYCLIN-DEPENDENT KINASE-5 REGULATES SYNAPTIC VESICLE SPATIAL DISTRIBUTION AND RECRUITMENT TO RECYCLING POOL AT HIPPOCAMPAL SYNAPSES. 75
Altered Mechanisms Underlying the Abnormal Glutamate Release in Amyotrophic Lateral Sclerosisat a Pre-Symptomatic Stage of the Disease. 75
Altered synaptic mechanisms and excessive glutamate release in amyotrophic lateral sclerosis 75
Alterations of Synaptic Mechanisms and Excessive Glutamate Release in the Spinal Cord of SOD1G93A Mice 72
LRRK2 BINDS TO NEURONAL VESICLES THROUGH PROTEIN INTERACTIONS MEDIATED BY ITS C-TERMINAL WD40 DOMAIN. 68
SYN1loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function 67
LRRK2 interacts with synaptic vesicles in the nerve terminal 65
The translocation of focal adhesion kinase in brain synaptosomes is regulated by phosphorylation and actin assembly 64
Alterations of Synaptic Mechanisms and Excessive Glutamate Release in the Spinal Cord of SOD1G93A Mice 64
Phosphatidylinositol 4-kinase type IIα is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. 63
LRRK2 INTERACTS WITH SYNAPTIC VESICLES AT THE PRESYNAPTIC SITE. 63
Synaptic mechanisms underlying the excessive and precocious glutamate release in the spinal cord of SOD1G93A experimental mice 62
Biochimica del Sistema Nervoso 61
Molecular mechanisms supporting abnormal glutamate release in the spinal cord of a mouse model of Amyotrophic Lateral Sclerosis. 60
Presynaptic L-Type Ca 2+ Channels Increase Glutamate Release Probability and Excitatory Strength in the Hippocampus during Chronic Neuroinflammation 57
Molecular mechanism underlying excessive and precocious glutamate release in the spinal cord of the SOD1G93A mouse model of amyotrophic lateral sclerosis. 56
LRRK2 interacts with synaptic vesicles at the presynaptic level 56
Synaptic Mechanisms Sustaining The Excessive And Precocious Glutamate Release In The Spinal Cord Of SOD1G93A Mice 56
Abnormal and precocious exocytotic release of glutamate in the spinal cord of a mouse model of amyotrophic lateral sclerosis. 55
Synaptic mechanisms of the abnormal release of glutamate in the spinal cord of pre-symptomatic SOD1G93A mice 54
The protein kinase LRRK2 is involved in neurotransmitter release by interacting and phosphorylating synapsin I in nerve terminals 49
PRRT2 modulates presynaptic Ca2+ influx by interacting with P/Q-type channels 45
Temperature-Dependent Olive Pomace Extraction for Obtaining Bioactive Compounds Preventing the Death of Murine Cortical Neurons 42
Rest/nrsf drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion 37
The LRRK2 N-terminal domain influences vesicle trafficking: impact of the E193K variant 28
Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates 9
Totale 6.809
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Categoria #
all - tutte 20.073
article - articoli 13.802
book - libri 0
conference - conferenze 5.546
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 725
Totale 40.146
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.434 0 0 0 0 153 214 259 108 142 306 199 53
2020/2021627 30 46 44 45 15 63 77 61 46 87 47 66
2021/2022860 38 47 65 81 13 70 39 215 46 93 41 112
2022/2023840 81 73 10 118 142 153 6 41 117 1 80 18
2023/2024468 22 72 7 55 43 69 43 23 24 7 33 70
2024/2025440 83 108 43 97 109 0 0 0 0 0 0 0
Totale 6.809