IRIS
NENCIONI, ALESSIO
 Distribuzione geografica
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Continente #
EU - Europa 20.611
Totale 20.611
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Nazione #
IT - Italia 20.611
Totale 20.611
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Città #
Genova 14.683
Genoa 2.308
Rapallo 2.297
Vado Ligure 1.279
Bordighera 44
Totale 20.611
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Nome #
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 181
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 178
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 177
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 175
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 173
Autophagy in blood cancers: biological role and therapeutic implications. 172
Update on cardiotoxicity of anti-cancer treatments 171
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 170
The vulnerable coronary plaque: update on imaging technologies. 167
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 167
Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination. 167
Clinical characteristics, management and in-hospital mortality of patients with COVID-19 In Genoa, Italy 166
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics 163
Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience. 161
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 160
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 158
Simulation-Based Education for Physicians to Increase Oral Anticoagulants in Hospitalized Elderly Patients with Atrial Fibrillation 158
APO866 activity in hematologic malignancies: a preclinical in vitro study. 157
Pathophysiological role of neutrophils in acute myocardial infarction. 154
Anticancer vaccination strategies. 154
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 153
Ras-induced resistance to lapatinib is overcome by MEK inhibition 149
Discovery of novel and selective SIRT6 inhibitors. 148
Pegfilgrastim compared with filgrastim after autologous peripheral blood stem cell transplantation in patients with solid tumours and lymphomas. 148
Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives. 147
Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond. 147
Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation 147
An emerging role of glucagon-like Peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes. 146
Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes. possible relevance to the assays for the detection of micrometastatic breast cancer 145
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model 145
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice 145
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 144
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 143
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 143
Fasting and cancer: molecular mechanisms and clinical application 142
Sirt6 regulates dendritic cell differentiation, maturation, and function 140
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells 140
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 140
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 139
Peripheral blood vs. bone marrow for molecular monitoring of BCR-ABL1 levels in chronic myelogenous leukemia, a retrospective analysis in allogeneic bone marrow recipients. 138
Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response 137
Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. 135
Evidence on the pathogenic role of auto-antibodies in acute cardiovascular diseases. 135
Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction. 135
Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics. 133
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 133
Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? 133
Molecular diagnosis and monitoring of chronic myelogenous leukemia: BCR-Abl and more. 133
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters. 133
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 132
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 132
The In-Hospital Length of Stay after Hip Fracture in Octogenarians: Do Delirium and Dementia Shape a New Care Process? 131
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 131
Carvedilol Prevents Doxorubicin-induced Free Radical release and Oxidative Damage in Cardiomyocytes. 129
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. 128
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1 128
Evaluation of prognostic indices in elderly hospitalized patients 125
Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells 124
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA 124
Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation 124
New insights into biology of chronic myeloid leukemia: implications in therapy. 123
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 122
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 122
Evaluating treatment response of chronic myeloid leukemia: emerging science and technology. 121
Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards 121
ANTITUMOR ACTIVITY OF NAMPT INHIBITION AND SYNERGY WITH CYCLOSPORIN A AND HDACIS TO PROMOTE APOPTOSIS IN PRIMARY LEUKEMIC CELLS 121
Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells. 120
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 120
Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment 119
Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer. 119
Immunotherapy with dendritic cells for cancer 118
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 118
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 118
The use of dendritic cells in cancer immunotherapy. 118
The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. 117
Selectivity hot-spots of sirtuin catalytic cores 117
Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes. 116
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer 116
Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity. 116
Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum. 115
The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level 115
vitamin C, aging and Alzheimer's disease 115
The proteasome and its inhibitors in immune regulation and immune disorders. 114
Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice. 114
Targeting NAD(+) Salvage Pathway Induces Autophagy in Multiple Myeloma Cells 113
New perspectives in dendritic cell-based cancer immunotherapy. 112
Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status 112
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. 112
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 112
Activation of the death receptor apoptosis pathway by TRAIL overcomes anticancer drug resisitance in antiapoptotic bcl-2 family members expressing lymphoma cells 111
Rejuvenating sirtuins: the rise of a new family of cancer drug targets 111
Nicotinic acid: A case for a vitamin that moonlights for cancer? 110
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 110
Transfection of dendritic cells with RNA induces CD4- and CD8-mediated T cell immunity against breast carcinomas and reveals the immunodominance of presented T cell epitopes. 110
Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis 109
Cellular immunotherapy with dendritic cells in cancer: current status. 108
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives 108
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration 108
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols. 107
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems 107
Totale 13.428
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Categoria #
all - tutte 68.381
article - articoli 65.502
book - libri 0
conference - conferenze 1.329
curatela - curatele 0
other - altro 0
patent - brevetti 1.035
selected - selezionate 0
volume - volumi 515
Totale 136.762
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.484 0 0 0 0 521 644 847 411 505 821 533 202
2020/20212.002 105 193 180 171 188 166 94 192 152 243 165 153
2021/20222.585 77 198 172 339 116 202 134 536 133 251 121 306
2022/20232.805 281 270 35 310 478 389 14 199 414 54 317 44
2023/20241.754 58 180 57 254 189 309 117 115 70 33 110 262
2024/20251.447 235 339 115 407 351 0 0 0 0 0 0 0
Totale 21.108