IRIS
NENCIONI, ALESSIO
 Distribuzione geografica
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Continente #
EU - Europa 19.321
Totale 19.321
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Nazione #
IT - Italia 19.321
Totale 19.321
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Città #
Genova 14.599
Genoa 2.350
Rapallo 2.328
Bordighera 44
Totale 19.321
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Nome #
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. 176
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of AKT-mediated gene repression 174
1222 POSTER Chemical Screening for Potentiators of Lapatinib Activity in Human Breast Cancer 173
1221 POSTER Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 170
APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells 168
Autophagy in blood cancers: biological role and therapeutic implications. 167
Update on cardiotoxicity of anti-cancer treatments 166
The vulnerable coronary plaque: update on imaging technologies. 164
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents 164
Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair. 161
Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination. 160
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics 155
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells 154
Simulation-Based Education for Physicians to Increase Oral Anticoagulants in Hospitalized Elderly Patients with Atrial Fibrillation 153
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 153
Pathophysiological role of neutrophils in acute myocardial infarction. 149
APO866 activity in hematologic malignancies: a preclinical in vitro study. 148
Anticancer vaccination strategies. 148
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 147
Ras-induced resistance to lapatinib is overcome by MEK inhibition 143
Pegfilgrastim compared with filgrastim after autologous peripheral blood stem cell transplantation in patients with solid tumours and lymphomas. 143
Discovery of novel and selective SIRT6 inhibitors. 142
Clinical characteristics, management and in-hospital mortality of patients with COVID-19 In Genoa, Italy 142
Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation 142
Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives. 141
An emerging role of glucagon-like Peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes. 140
Fasting and cancer: molecular mechanisms and clinical application 140
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model 139
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. 139
Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes. possible relevance to the assays for the detection of micrometastatic breast cancer 138
Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond. 138
Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors As Therapeutics: Rationales, Controversies, Clinical Experience. 138
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. 136
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice 136
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects 134
Peripheral blood vs. bone marrow for molecular monitoring of BCR-ABL1 levels in chronic myelogenous leukemia, a retrospective analysis in allogeneic bone marrow recipients. 134
Catastrophic NAD(+) Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE 132
Sirt6 regulates dendritic cell differentiation, maturation, and function 131
Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. 131
Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response 130
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters. 130
Evidence on the pathogenic role of auto-antibodies in acute cardiovascular diseases. 129
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 128
Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics. 127
Molecular diagnosis and monitoring of chronic myelogenous leukemia: BCR-Abl and more. 127
Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction. 127
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. 126
Carvedilol Prevents Doxorubicin-induced Free Radical release and Oxidative Damage in Cardiomyocytes. 126
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. 126
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition 126
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells 125
Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? 125
The In-Hospital Length of Stay after Hip Fracture in Octogenarians: Do Delirium and Dementia Shape a New Care Process? 124
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1 123
Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells 122
New insights into biology of chronic myeloid leukemia: implications in therapy. 120
Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation 118
Evaluation of prognostic indices in elderly hospitalized patients 118
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells 117
Evaluating treatment response of chronic myeloid leukemia: emerging science and technology. 116
Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition. 116
Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards 116
Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells. 115
Chemical-genetic Screenings for Synthetic-lethal Interactions in Breast Cancer 115
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 115
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA 115
Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer. 115
Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes. 114
Nicotinamide Phosphoribosyltransferase As A Target In Inflammation-Related Disorders. 114
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer 113
Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum. 112
Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity. 112
The use of dendritic cells in cancer immunotherapy. 112
ANTITUMOR ACTIVITY OF NAMPT INHIBITION AND SYNERGY WITH CYCLOSPORIN A AND HDACIS TO PROMOTE APOPTOSIS IN PRIMARY LEUKEMIC CELLS 112
The proteasome and its inhibitors in immune regulation and immune disorders. 111
Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer 110
The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. 110
Selectivity hot-spots of sirtuin catalytic cores 110
The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level 110
New perspectives in dendritic cell-based cancer immunotherapy. 109
Immunotherapy with dendritic cells for cancer 109
vitamin C, aging and Alzheimer's disease 109
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. 109
Targeting NAD(+) Salvage Pathway Induces Autophagy in Multiple Myeloma Cells 108
Hedgehog Signaling Is Useful as a Novel Molecular Marker for Predicting Relapse and Resistance During Chronic Myeloid Leukemia Treatment 108
Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status 108
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules 108
Activation of the death receptor apoptosis pathway by TRAIL overcomes anticancer drug resisitance in antiapoptotic bcl-2 family members expressing lymphoma cells 107
Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice. 107
Transfection of dendritic cells with RNA induces CD4- and CD8-mediated T cell immunity against breast carcinomas and reveals the immunodominance of presented T cell epitopes. 106
Cellular immunotherapy with dendritic cells in cancer: current status. 105
Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis 105
Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives 105
Nicotinic acid: A case for a vitamin that moonlights for cancer? 105
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 104
Rejuvenating sirtuins: the rise of a new family of cancer drug targets 104
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols. 103
Crosspresentation: a matter of pH. 103
Intracellular NAD+ depletion induces autophagic-death in Multiple Myeloma cells 102
Targeting NAD+ Salvage Pathway Induces Autophagy in Multiple Myeloma Cells via mTORC1 and Extracellular Signal-Regulated Kinase (ERK1/2) Inhibition 101
Totale 12.791
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Categoria #
all - tutte 59.510
article - articoli 57.195
book - libri 0
conference - conferenze 1.104
curatela - curatele 0
other - altro 0
patent - brevetti 788
selected - selezionate 0
volume - volumi 423
Totale 119.020
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20205.475 243 122 193 465 517 642 839 408 502 815 529 200
2020/20212.016 105 192 188 170 189 169 95 194 154 244 165 151
2021/20222.585 77 200 166 339 116 201 134 539 134 252 121 306
2022/20232.846 281 273 36 315 477 392 15 209 418 58 325 47
2023/20241.788 67 181 59 259 191 315 112 122 72 34 111 265
2024/2025160 160 0 0 0 0 0 0 0 0 0 0 0
Totale 19.813