Nome |
# |
Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status, file e268c4c9-a2df-a6b7-e053-3a05fe0adea1
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544
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Fasting-mimicking diet and hormone therapy induce breast cancer regression, file 1602dfb4-1f6a-4ed0-ba22-bfdef1c97c9d
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281
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Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation, file e268c4c6-025d-a6b7-e053-3a05fe0adea1
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265
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Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors and DNA repair., file e268c4c9-bf2c-a6b7-e053-3a05fe0adea1
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235
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Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA, file e268c4ca-8733-a6b7-e053-3a05fe0adea1
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122
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Sirt6 regulates dendritic cell differentiation, maturation, and function, file e268c4c7-989f-a6b7-e053-3a05fe0adea1
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117
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Nutrients in the Prevention of Alzheimer's Disease, file e268c4cb-4328-a6b7-e053-3a05fe0adea1
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110
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Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies., file e268c4c9-e0fd-a6b7-e053-3a05fe0adea1
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108
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Fasting potentiates the anticancer activity of tyrosin kinase inhibitors by strenghtening MAPK signalling inhibition., file e268c4ca-0d6f-a6b7-e053-3a05fe0adea1
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100
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The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs, file e268c4cb-4326-a6b7-e053-3a05fe0adea1
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95
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Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8, file e268c4c9-cdb5-a6b7-e053-3a05fe0adea1
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91
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Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial, file e268c4c9-a7a7-a6b7-e053-3a05fe0adea1
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89
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EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition, file e268c4c9-ae5e-a6b7-e053-3a05fe0adea1
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88
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The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level, file e268c4c9-a7a4-a6b7-e053-3a05fe0adea1
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83
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vitamin C, aging and Alzheimer's disease, file e268c4c7-fe8b-a6b7-e053-3a05fe0adea1
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82
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Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link?, file e268c4c8-8f82-a6b7-e053-3a05fe0adea1
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63
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Fasting plus tyrosine kinase inhibitors in cancer, file e268c4ca-3abb-a6b7-e053-3a05fe0adea1
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63
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Fasting and cancer: molecular mechanisms and clinical application, file e268c4ce-4f48-a6b7-e053-3a05fe0adea1
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51
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APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells, file e268c4cf-0b27-a6b7-e053-3a05fe0adea1
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44
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Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent, file e268c4cc-9070-a6b7-e053-3a05fe0adea1
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42
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Quantitative Image Analysis Of Proliferation And Microvessels Density In A Mouse Xenograft Model Of Breast Cancer, file e268c4c9-6dd0-a6b7-e053-3a05fe0adea1
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41
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Nicotinic acid: A case for a vitamin that moonlights for cancer?, file e268c4cb-7f75-a6b7-e053-3a05fe0adea1
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38
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Neuropsychiatric Disorders and Frailty in Older Adults over the Spectrum of Cancer: A Narrative Review, file e268c4ce-3781-a6b7-e053-3a05fe0adea1
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36
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Clinical characteristics, management and in-hospital mortality of patients with COVID-19 In Genoa, Italy, file e268c4cc-c929-a6b7-e053-3a05fe0adea1
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25
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Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model, file e268c4cc-5ff2-a6b7-e053-3a05fe0adea1
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21
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Medication management ability in older patients: Time for a reappraisal, file e268c4ca-3c0d-a6b7-e053-3a05fe0adea1
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17
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Comprehensive geriatric assessment in older adults with cancer: recommendations by the Italian Society of Geriatrics and Gerontology (SIGG), file e268c4cd-ebc6-a6b7-e053-3a05fe0adea1
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16
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Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia, file e268c4ce-e457-a6b7-e053-3a05fe0adea1
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15
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Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells vulnerability to DNA-damaging agents, file e268c4ca-8944-a6b7-e053-3a05fe0adea1
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7
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Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration, file e268c4cc-e505-a6b7-e053-3a05fe0adea1
|
7
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Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy, file f2e2c9fe-0015-4107-81ef-fb915010dffd
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6
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Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics, file e268c4c9-a711-a6b7-e053-3a05fe0adea1
|
5
|
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice, file e268c4cd-7452-a6b7-e053-3a05fe0adea1
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5
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Social vulnerability is associated with increased mortality in older patients with cancer, file e268c4cd-f958-a6b7-e053-3a05fe0adea1
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5
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Simulation-Based Education for Physicians to Increase Oral Anticoagulants in Hospitalized Elderly Patients with Atrial Fibrillation, file e268c4ca-57c9-a6b7-e053-3a05fe0adea1
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4
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NAD+ Levels Control T Cell Calcium Signaling and Activation, file e268c4cb-7f74-a6b7-e053-3a05fe0adea1
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4
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Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells, file e268c4cd-90b9-a6b7-e053-3a05fe0adea1
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4
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SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma, file 0a93a83c-2ad0-4166-a855-4f9a9debea2d
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3
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Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery, file 7b43c5ca-86d8-437f-a42a-4be284108c9d
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3
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Effect of SARS-CoV-2 vaccination in a vulnerable COVID-19 cohort: a real-life experience in an Italian Hospital, file 9d8440f6-54d0-4395-8baa-8d1261bb71bd
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3
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Vitamin D and Folate as Predictors of {MMSE} in Alzheimer's Disease: A Machine Learning Analysis, file aa7c9297-9490-43d6-b584-33dbfef5a87c
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3
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Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors, file b46a21fc-b4c9-4476-8a65-6d079e6ca92c
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3
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Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells., file e268c4c5-fb8c-a6b7-e053-3a05fe0adea1
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3
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Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer, file e268c4c7-98e5-a6b7-e053-3a05fe0adea1
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3
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Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules, file e268c4ca-4115-a6b7-e053-3a05fe0adea1
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3
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Appropriateness of prescription of oral anticoagulant therapy in acutely hospitalized older people with atrial fibrillation. Secondary analysis of the SIM-AF cluster randomized clinical trial, file e268c4ca-dc5b-a6b7-e053-3a05fe0adea1
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3
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null, file e268c4ca-efa4-a6b7-e053-3a05fe0adea1
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3
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Fasting and cancer: molecular mechanisms and clinical application, file e268c4cb-9d38-a6b7-e053-3a05fe0adea1
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3
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Multiparametric Evaluation of Geriatric Patients Admitted to Intermediate Care: Impact on Geriatric Rehabilitation, file 0c4a2dc1-6a3a-4acb-8e22-7556582bc7da
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2
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Pegfilgrastim compared with filgrastim after autologous peripheral blood stem cell transplantation in patients with solid tumours and lymphomas., file e268c4c6-14d6-a6b7-e053-3a05fe0adea1
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2
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Evaluation of prognostic indices in elderly hospitalized patients, file e268c4ca-12a2-a6b7-e053-3a05fe0adea1
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2
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Development of a predictor of one-year mortality in older patients with cancer by geriatric and oncologic parameters, file e268c4cc-1058-a6b7-e053-3a05fe0adea1
|
2
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APO866 increases antitumor activity of cyclosporin - A by inducing mitochondrial and endoplasmic reticulum stress in leukemia cells, file e268c4cc-56b4-a6b7-e053-3a05fe0adea1
|
2
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Fasting-mimicking diet and hormone therapy induce breast cancer regression, file e268c4cd-1080-a6b7-e053-3a05fe0adea1
|
2
|
Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment, file e268c4ce-5ee8-a6b7-e053-3a05fe0adea1
|
2
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Fasting and Cognitive Impairment, file cf397050-73b0-4862-a0ba-3176052b49f1
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1
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Potential Predictors for Cognitive Decline in Vascular Dementia: A Machine Learning Analysis, file d21efd6b-aa57-4fad-92ce-f8005ce4bacf
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1
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Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells., file e268c4c5-f8c0-a6b7-e053-3a05fe0adea1
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1
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Proteasome inhibitors: antitumor effects and beyond, file e268c4c5-fc17-a6b7-e053-3a05fe0adea1
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1
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Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells., file e268c4c6-078d-a6b7-e053-3a05fe0adea1
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1
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The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts, file e268c4c6-0f86-a6b7-e053-3a05fe0adea1
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1
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Statin Treatment Is Associated with Reduction in Serum Levels of Receptor Activator of NF-kappaB Ligand and Neutrophil Activation in Patients with Severe Carotid Stenosis., file e268c4c6-c605-a6b7-e053-3a05fe0adea1
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1
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Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques., file e268c4c6-d1e7-a6b7-e053-3a05fe0adea1
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1
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Personality traits and behavioral disturbances in dementia: A new risk factor?, file e268c4c7-e08e-a6b7-e053-3a05fe0adea1
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1
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Use of oral anticoagulant drugs in older patients with atrial fibrillation in internal medicine wards, file e268c4c9-07e8-a6b7-e053-3a05fe0adea1
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1
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Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response, file e268c4c9-a2da-a6b7-e053-3a05fe0adea1
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1
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Update on cardiotoxicity of anti-cancer treatments, file e268c4c9-c899-a6b7-e053-3a05fe0adea1
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1
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Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin., file e268c4c9-c8aa-a6b7-e053-3a05fe0adea1
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1
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Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice., file e268c4ca-176c-a6b7-e053-3a05fe0adea1
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1
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Selectivity hot-spots of sirtuin catalytic cores, file e268c4ca-1f37-a6b7-e053-3a05fe0adea1
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1
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Reply to 'Fasting in oncology: a word of caution', file e268c4ca-3a39-a6b7-e053-3a05fe0adea1
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1
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Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model, file e268c4ca-4100-a6b7-e053-3a05fe0adea1
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1
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Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells, file e268c4ca-4360-a6b7-e053-3a05fe0adea1
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1
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The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer., file e268c4ca-5710-a6b7-e053-3a05fe0adea1
|
1
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The In-Hospital Length of Stay after Hip Fracture in Octogenarians: Do Delirium and Dementia Shape a New Care Process?, file e268c4ca-5e72-a6b7-e053-3a05fe0adea1
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1
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SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects, file e268c4ca-650d-a6b7-e053-3a05fe0adea1
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1
|
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells, file e268c4ca-7f8d-a6b7-e053-3a05fe0adea1
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1
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Reisitin: A reappraisal, file e268c4ca-d109-a6b7-e053-3a05fe0adea1
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1
|
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters., file e268c4ca-d10b-a6b7-e053-3a05fe0adea1
|
1
|
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems, file e268c4ca-f3ca-a6b7-e053-3a05fe0adea1
|
1
|
Algoplus®Scale in Older Patients with Dementia: A Reliable Real-World Pain Assessment Tool, file e268c4cc-105d-a6b7-e053-3a05fe0adea1
|
1
|
Simulation-Based Education for Physicians to Increase Oral Anticoagulants in Hospitalized Elderly Patients with Atrial Fibrillation, file e268c4cc-32db-a6b7-e053-3a05fe0adea1
|
1
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Dual NAMPT and BTK targeting leads to synergistic killing of Waldenström macroglobulinemia cells regardless of MYD88 and CXCR4 somatic mutation status, file e268c4cd-6ab8-a6b7-e053-3a05fe0adea1
|
1
|
Totale |
3.004 |