IRIS
SCHETTINI, GENNARO
 Distribuzione geografica
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Continente #
EU - Europa 9.922
Totale 9.922
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Nazione #
IT - Italia 9.922
Totale 9.922
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Città #
Genova 7.939
Rapallo 1.015
Genoa 750
Vado Ligure 187
Bordighera 31
Totale 9.922
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Nome #
Amyloid precursor protein modulates ERK1/2 signaling 151
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 145
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 143
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 141
The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications 136
Characterization of chemokines and their receptors in the central nervous system: physiopathological implications 135
SDF1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent cytosolic tyrosine kinase, Pyk2. 131
Steroid modulation of prolactin release from single lactotropes in male and female rats studied by the reverse hemolytic plaque assay 128
b25-35 alters calcium homeostasis and induces neurotoxicity in cerebellar granule cells 125
Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases 123
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 121
p38 MAP Kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells 121
Antisense oligonucleotides as therapeutic agents. 121
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 119
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation 119
Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. 118
Age-related alterations of somatostatin gene expression in different rat brain areas 118
Apoptotic cell death and amyloid precursor protein signaling in neuroblastoma SH-SY5Y cells. 115
Chemokines and their receptors in the central nervous system 115
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 115
Isolation of a long-lasting eag-related gene type K+ current in MMQ lactotrophs and its accomodating role during slow firing and prolactin release 114
Overexpression of cyclin D1 is associated with poor survival in epithelial ovarian cancer. 114
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 114
Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line. 113
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein 112
Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas 112
Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation 109
The tyrosine phosphatase Shp-2 mediates intracellular signaling initiated by Ret mutants 109
Multiple intracellular effectors modulate physiological functions of the cloned somatostatin receptors 106
Interleukin 6 modulation of second messenger systems in anterior pituitary cells 106
Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2 106
Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126- induced astroglial proliferation 105
Chemokine stromal cell-derived factor 1α induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals 104
Pyroglutamate-modified amyloid beta-peptides-abetaN3(pE)- strongly affect cultured neuron and astrocyte survival 104
Somatostatin inhibition of adenylate cyclase activity in different brain areas 103
Chemokines, their receptors and significance in brain function. 102
Adenosine and its analogue N-6-¬phenylisopropyladenosine (PIA) modulate anterior pituitary adenylate cyclase activity and prolactin secretion 102
Somatostatin inhibits interleukin 6 release from rat cortical type I astrocytes, via the inhibition of adenylyl cyclase 102
Molecular mechanisms mediating neuronal cell death in experimental models of prion diseases, in vitro 102
Generation of an apoptotic intracellular peptdide by g-secretase cleavage of Alzheimer’s amyliod b-protein precursor. 101
Dihydropyridine modulation of voltage-activated calcium channels in PC12 cells: effect of pertussis toxin pretreatment 101
Somatostatin inhibition of anterior pituitary adenylate cyclase activity: different sensitivity between male and female rats 100
CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line. 100
Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK1,2 signaling 100
Pertussis toxin pretreatment abolishes dihydropyridine inhibition of calcium flux in the 235-1 pituitary cell line 98
Role of G-proteins in mediating dihydropyridine receptor coupling with voltage sensitive calcium channels 98
The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation 95
INTRACELLULAR MECHANISMS MEDIATING THE NEURONAL CELL DEATH AND ASTROGLIOSIS INDUCED BY THE PRION PROTEIN FRAGMENT 106-126 94
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities” 94
TGF-beta1 prevents gp120-induced impairment of Ca++ homeostasis and rescues cortical neurons from apoptotic death 93
Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide 93
Molecular mechanisms mediating the effects of L-alpha-glyceryl phosphorylcholine, a new cognition enhancing drug, on behavioral and biochemical parameters in young and aged rats 92
Dopamine and somatostatin inhibition of prolactin secretion from MMQ pituitary cells: role of adenosine triphosphate-sensitive potassium channels 91
Opposite role of apolipoprotein E in normal brain and Alzheimer's disease 90
Chemosensitivity of glioblastoma cells during treatment with the organo-tin compound triethyltin (IV) lupinylsulfide hydrochloride. 90
Interleukin 1beta inhibition of TRH-stimulated prolactin secretion and phosphoinositides metabolism 90
CXC receptors and chemokines expression in human meningioma: SDF1/CXCR4 signaling activates ERK1/2 and stimulates meningioma cell proliferation 89
Oncogene transformation of PC Cl3 clonal thyroid cell line induces an autonomous pattern of proliferation that correlates with a loss of basal and stimulated phosphotyrosine phosphatase activity 86
Identification of a conserved N-capping box important for the structural autonomy of the prion alpha 3-helix: the disease associated D202N mutation destabilizes the helical conformation 85
Apoptotic cell death influences the signaling activity pf the Amyloid Precursor Protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y. 84
Beta amyloid a disease target or a synaptic regulator affecting age-related neurotransmitter changes 84
Molecular mechanisms involved in the aggregation and fibril formation of the recombinant human prion fragment PrP90-231 84
BACE1 overexpression regulates amyloid precursor protein cleavage and interaction with the ShcA adapter. 83
Expression of chemokine receptors in the rat brain 83
Effect of interleukin 1beta on transducing mechanisms in 235-1 clonal pituitary cells. Part 1: modulation of adenylate cyclase activity 81
In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormone-secreting human pituitary adenomas 80
Somatostatin and SMS 201-995 reversal of the impairment of cognitive functions induced by cysteamine depletion of brain somatostatin 80
alpha-Glycerylphosphorylethanolamine rescues astrocytes from mitochondrial impairment and oxidative stress induced by amyloid beta-peptides. 80
beta-Amyloid precursor protein metabolism: focus on the functions and degradation of its intracellular domain 78
Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand SDF1 77
Influence of trastuzumab on epirubicin pharmacokinetics in metastatic breast cancer patients 77
Dihydroergotoxine treatment improves active avoidance performance and increases dopamine-stimulated adenylate cyclase activity, in young and aged rats 76
Intracellular signalling mediating HIV-1 gp120 neurotoxicity 76
Role of interleukin-6 in the neuroendocrine system 75
Nicotinic component of galantamine in the regulation of amyloid precursor protein processing 75
Intracellular transducing mechanisms modulated by activated brain somatostatin receptors 75
Expression of the chemokine receptor CXCR4 and its ligand stromal-cell derived factor 1 (SDF1) in human brain tumors and their involvement in glial proliferation, in vitro 74
Molecular consequences of presenilin-1 mutation. 73
Proteasome inhibitors induce cerebellar granule cell death: inhibition of NF-kB activation 73
Somatostatin and its analog lanreotide inhibit the proliferation of dispersed human non-functioning pituitary adenoma cells in vitro 73
Interleukin 1 modulation of anterior pituitary function: effect on hormone release and second messenger systems 71
The activation of the phosphotyrosine phosphatase h (r-PTPh) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 71
Somatostatin controls Kaposi sarcoma growth through inhibition of angiogenesis 71
N-terminally modified amyloid b- peptides and Alzheimer’s disease. 70
Antiemetic effect of the levo isomer of sulpiride (L-sulpiride) in humans 70
Interleukin-6 mediates neural-immune interactions: study on prolactin release and intracellular transducing mechanisms 68
Stromal cell-derived factor-1 alpha induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway 67
alpha1B, but not alpha1A, adrenoreceptor activates calcium influx through the stimulation of a tyrosine kinase/phosphotyrosine phosphatase pathway, following noradrenaline-induced emptying of IP3 sensitive calcium stores, in PC Cl3 thyroid cell line 67
Somatostatinergic control of Kaposi’s sarcoma growth through the inhibition of angiogenesis 67
Calmodulin modulates prolactin secretion by anterior pituitary cells in vitro: studies with calmodulin containing liposomes 66
Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and or transcriptional role. Relevance for Alzheimer pathology. Journal of Neurochemistry. 65
Expression of somatostatin receptors mRNA in human meningiomas and their implication in in vitro antiproliferative activity 65
Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform 64
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue 61
Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferaton and migration. 59
Fipexide improvement of cognitive functions in rat: behavioral and neurochemical studies 59
Interleukin 1 modulation of anterior pituitary function: effects on prolactin release and post-receptor transducing mechanisms 59
SOMATOSTATIN INHIBITS PC CL3 THYROID CELL PROLIFERATION THROUGH THE MODULATION OF PHOSPHOTYROSINE PHOSPHATASE ACTIIVTY 59
Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. 58
Modulation by GTP of basal and agonist-stimulated striatal adenylate cyclase activity following chronic blockade of D-1 and D-2 dopamine receptors: involvement of G-proteins in the development of dopamine receptor super-sensitivity 58
Totale 9.395
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Categoria #
all - tutte 28.576
article - articoli 27.912
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 664
Totale 57.152
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.401 0 0 109 119 216 278 390 135 198 491 351 114
2020/2021474 32 40 47 28 23 39 31 50 62 46 37 39
2021/20221.372 24 180 60 189 28 69 112 310 24 105 57 214
2022/20231.220 127 77 14 142 192 248 3 86 217 7 94 13
2023/2024551 36 90 16 59 39 105 31 40 45 6 21 63
2024/2025212 63 142 7 0 0 0 0 0 0 0 0 0
Totale 9.968