IRIS
SCHETTINI, GENNARO
 Distribuzione geografica
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Continente #
EU - Europa 10.283
Totale 10.283
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Nazione #
IT - Italia 10.283
Totale 10.283
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Città #
Genova 7.939
Rapallo 1.015
Genoa 750
Vado Ligure 548
Bordighera 31
Totale 10.283
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Nome #
Amyloid precursor protein modulates ERK1/2 signaling 161
Characterization of the pro-apoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231 151
Apoptotic cell death and impairment of L-type voltage sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 150
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis 148
The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications 139
Characterization of chemokines and their receptors in the central nervous system: physiopathological implications 137
SDF1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent cytosolic tyrosine kinase, Pyk2. 136
Steroid modulation of prolactin release from single lactotropes in male and female rats studied by the reverse hemolytic plaque assay 130
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic 129
b25-35 alters calcium homeostasis and induces neurotoxicity in cerebellar granule cells 127
Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases 127
Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro 126
Antisense oligonucleotides as therapeutic agents. 125
p38 MAP Kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells 124
Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation 124
The phosphotyrosine phosphatase PTPh mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2 122
Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. 121
Age-related alterations of somatostatin gene expression in different rat brain areas 121
Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas 120
Chemokines and their receptors in the central nervous system 119
Isolation of a long-lasting eag-related gene type K+ current in MMQ lactotrophs and its accomodating role during slow firing and prolactin release 118
Apoptotic cell death and amyloid precursor protein signaling in neuroblastoma SH-SY5Y cells. 118
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 118
Overexpression of cyclin D1 is associated with poor survival in epithelial ovarian cancer. 117
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein 117
Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line. 114
Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation 112
Pyroglutamate-modified amyloid beta-peptides-abetaN3(pE)- strongly affect cultured neuron and astrocyte survival 111
The tyrosine phosphatase Shp-2 mediates intracellular signaling initiated by Ret mutants 111
Interleukin 6 modulation of second messenger systems in anterior pituitary cells 110
Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126- induced astroglial proliferation 109
Amyloid precursor protein and presenilin1 interact with the adaptor GRB2 and modulate ERK1,2 signaling 109
Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2 109
Chemokine stromal cell-derived factor 1α induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals 108
Multiple intracellular effectors modulate physiological functions of the cloned somatostatin receptors 108
Chemokines, their receptors and significance in brain function. 107
Somatostatin inhibition of adenylate cyclase activity in different brain areas 106
Molecular mechanisms mediating neuronal cell death in experimental models of prion diseases, in vitro 106
Dihydropyridine modulation of voltage-activated calcium channels in PC12 cells: effect of pertussis toxin pretreatment 105
Adenosine and its analogue N-6-¬phenylisopropyladenosine (PIA) modulate anterior pituitary adenylate cyclase activity and prolactin secretion 104
Somatostatin inhibits interleukin 6 release from rat cortical type I astrocytes, via the inhibition of adenylyl cyclase 104
Generation of an apoptotic intracellular peptdide by g-secretase cleavage of Alzheimer’s amyliod b-protein precursor. 103
CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line. 103
Role of G-proteins in mediating dihydropyridine receptor coupling with voltage sensitive calcium channels 102
Somatostatin inhibition of anterior pituitary adenylate cyclase activity: different sensitivity between male and female rats 101
The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation 99
Pertussis toxin pretreatment abolishes dihydropyridine inhibition of calcium flux in the 235-1 pituitary cell line 99
INTRACELLULAR MECHANISMS MEDIATING THE NEURONAL CELL DEATH AND ASTROGLIOSIS INDUCED BY THE PRION PROTEIN FRAGMENT 106-126 98
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor 3 (SSTR3) mediated regulation of endothelial NOS and MAP kinase activities” 98
Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide 96
TGF-beta1 prevents gp120-induced impairment of Ca++ homeostasis and rescues cortical neurons from apoptotic death 95
Opposite role of apolipoprotein E in normal brain and Alzheimer's disease 94
Molecular mechanisms mediating the effects of L-alpha-glyceryl phosphorylcholine, a new cognition enhancing drug, on behavioral and biochemical parameters in young and aged rats 94
CXC receptors and chemokines expression in human meningioma: SDF1/CXCR4 signaling activates ERK1/2 and stimulates meningioma cell proliferation 94
Molecular mechanisms involved in the aggregation and fibril formation of the recombinant human prion fragment PrP90-231 93
Chemosensitivity of glioblastoma cells during treatment with the organo-tin compound triethyltin (IV) lupinylsulfide hydrochloride. 92
Dopamine and somatostatin inhibition of prolactin secretion from MMQ pituitary cells: role of adenosine triphosphate-sensitive potassium channels 92
Identification of a conserved N-capping box important for the structural autonomy of the prion alpha 3-helix: the disease associated D202N mutation destabilizes the helical conformation 91
Oncogene transformation of PC Cl3 clonal thyroid cell line induces an autonomous pattern of proliferation that correlates with a loss of basal and stimulated phosphotyrosine phosphatase activity 91
Interleukin 1beta inhibition of TRH-stimulated prolactin secretion and phosphoinositides metabolism 91
Apoptotic cell death influences the signaling activity pf the Amyloid Precursor Protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y. 87
Beta amyloid a disease target or a synaptic regulator affecting age-related neurotransmitter changes 87
BACE1 overexpression regulates amyloid precursor protein cleavage and interaction with the ShcA adapter. 85
Expression of chemokine receptors in the rat brain 85
Effect of interleukin 1beta on transducing mechanisms in 235-1 clonal pituitary cells. Part 1: modulation of adenylate cyclase activity 84
alpha-Glycerylphosphorylethanolamine rescues astrocytes from mitochondrial impairment and oxidative stress induced by amyloid beta-peptides. 83
In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormone-secreting human pituitary adenomas 82
Influence of trastuzumab on epirubicin pharmacokinetics in metastatic breast cancer patients 82
beta-Amyloid precursor protein metabolism: focus on the functions and degradation of its intracellular domain 81
Somatostatin and SMS 201-995 reversal of the impairment of cognitive functions induced by cysteamine depletion of brain somatostatin 81
Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand SDF1 80
Role of interleukin-6 in the neuroendocrine system 78
Dihydroergotoxine treatment improves active avoidance performance and increases dopamine-stimulated adenylate cyclase activity, in young and aged rats 78
Intracellular transducing mechanisms modulated by activated brain somatostatin receptors 78
Intracellular signalling mediating HIV-1 gp120 neurotoxicity 78
Expression of the chemokine receptor CXCR4 and its ligand stromal-cell derived factor 1 (SDF1) in human brain tumors and their involvement in glial proliferation, in vitro 77
Nicotinic component of galantamine in the regulation of amyloid precursor protein processing 77
Molecular consequences of presenilin-1 mutation. 75
Proteasome inhibitors induce cerebellar granule cell death: inhibition of NF-kB activation 75
Antiemetic effect of the levo isomer of sulpiride (L-sulpiride) in humans 74
Somatostatinergic control of Kaposi’s sarcoma growth through the inhibition of angiogenesis 74
Somatostatin and its analog lanreotide inhibit the proliferation of dispersed human non-functioning pituitary adenoma cells in vitro 74
The activation of the phosphotyrosine phosphatase h (r-PTPh) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation 73
Somatostatin controls Kaposi sarcoma growth through inhibition of angiogenesis 73
N-terminally modified amyloid b- peptides and Alzheimer’s disease. 72
Interleukin 1 modulation of anterior pituitary function: effect on hormone release and second messenger systems 72
Stromal cell-derived factor-1 alpha induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway 71
Interleukin-6 mediates neural-immune interactions: study on prolactin release and intracellular transducing mechanisms 70
Calmodulin modulates prolactin secretion by anterior pituitary cells in vitro: studies with calmodulin containing liposomes 69
alpha1B, but not alpha1A, adrenoreceptor activates calcium influx through the stimulation of a tyrosine kinase/phosphotyrosine phosphatase pathway, following noradrenaline-induced emptying of IP3 sensitive calcium stores, in PC Cl3 thyroid cell line 69
Expression of somatostatin receptors mRNA in human meningiomas and their implication in in vitro antiproliferative activity 68
Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and or transcriptional role. Relevance for Alzheimer pathology. Journal of Neurochemistry. 67
Neurotoxicity of the recombinant prion protein fragment 90-231 in SH-SY5Y cells is dependent on its conversion in beta-structured-isoform 66
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue 63
Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferaton and migration. 62
Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. 61
Modulation by GTP of basal and agonist-stimulated striatal adenylate cyclase activity following chronic blockade of D-1 and D-2 dopamine receptors: involvement of G-proteins in the development of dopamine receptor super-sensitivity 61
Interleukin 1 modulation of anterior pituitary function: effects on prolactin release and post-receptor transducing mechanisms 61
Inhibition of NF-kB activation induces apoptosis in cerebellar granule cells” 61
Fipexide improvement of cognitive functions in rat: behavioral and neurochemical studies 60
Totale 9.738
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Categoria #
all - tutte 30.291
article - articoli 29.594
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 697
Totale 60.582
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.173 0 0 0 0 216 278 390 135 198 491 351 114
2020/2021474 32 40 47 28 23 39 31 50 62 46 37 39
2021/20221.372 24 180 60 189 28 69 112 310 24 105 57 214
2022/20231.220 127 77 14 142 192 248 3 86 217 7 94 13
2023/2024551 36 90 16 59 39 105 31 40 45 6 21 63
2024/2025573 63 142 58 134 176 0 0 0 0 0 0 0
Totale 10.329