IRIS
PONTREMOLI, SANDRO
 Distribuzione geografica
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Continente #
EU - Europa 19.242
Totale 19.242
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Nazione #
IT - Italia 19.242
Totale 19.242
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Città #
Genova 15.497
Rapallo 1.858
Genoa 1.424
Vado Ligure 448
Bordighera 15
Totale 19.242
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Nome #
Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients 162
Role of the calpain-calpastatin system in the density-dependent growth arrest 153
Modulation of the calpain autoproteolysis by calpastatin and phospholipids 151
Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR. 150
Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients 150
A vincristine-resistant murine erythroleukemia cell line secretes a differentiation enhancing factor. 149
Effect of extremely low frequency magnetic fields on calpain activation 148
Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation. 146
Calpain inhibition promotes the rescue of F(508)del-CFTR in PBMC from cystic fibrosis patients. 145
Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. 142
Characterization of the calpastatin defect in erythrocytes from patients with essential hypertension. 139
Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor Complex. 139
Autolysis of human erythrocytes calpain produces two active enzyme forms with different cell localization 136
Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. 136
Extralysosomal protein degradation. 134
Interactions of Zn2+ and Mg2+ with rabbit liver fructose 1,6 bisphosphatase. 132
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.. 132
Characterization of the calpain/calpastatin system in human hemopoietic cell lines 132
Characterization of a new p94-like calpain form in human lymphocytes 131
Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency. 130
Pathological role of the calpain/calpastatin system in cystic fibrosis 130
Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. 129
Regulation of calpain activity in rat brain with altered Ca2+ homeostasis 129
On the mechanism of inhibition of fructose 1,6-bisphosphatase by fructose 2,6-bisphosphate. 129
Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin 129
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase. 128
Fructose-1, 6-diphosphatase from rabbit liver. 127
The role of calpain in the selective increased phosphorylation of the anion-transport protein in red cell of hypertensive subjects. 126
Characterization of the defective calpain-endogenous calpain inhibitor system in erythrocytes from Milan hypertensive rats. 126
Identification of a novel neutrophil membrane protein involved in modulation of oxidative burst. 125
Changes in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca(2+)-dependent proteolysis. 125
Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: structural requirements. 125
Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: purification and properties of the proenzymes. 125
Properties and intracellular localization of calpain activator protein 125
Cathepsin M: a lysosomal proteinase with aldolase-inactivating activity 123
Acyl-CoA-binding protein is a potent m-calpain activator 121
Changes during fasting in the activity of a specific lysosomal proteinase, fructose-1,6-bisphosphatase converting enzyme. 120
Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process. 120
The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte 119
Inactivation of fructose 1,6-bisphosphatase by a lysosomal proteinase is reversed by cystamine. 119
Cytosolic calcium dependent proteinase of human erythrocytes: formation of an enzyme-natural inhibitor complex induced by Ca2+ ions. 119
Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation 118
Binding of Zn2+ to rabbit muscle fructose 1,6-bisphosphatase and its effect on the catalytic properties. 118
Inactivation of liver aldolase in fasting rabbits: evidence for the accumulation of two different immunoreactive forms. 118
Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. 118
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. 117
The liver aldolase-fructose bisphosphatase complex. 117
The carboxy-terminal amino acid sequence of rabbit liver fructose 1,6-bisphosphatase. 117
Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. 117
Characterization of the inactive form of fructose-1,6-bisphosphate aldolase isolated from livers of fasted rabbits. 116
Rabbit liver fructose 1,6-diphosphatase. Properties of the native enzyme and their modification by subtilisin. 116
Degradation of CFTR-generated protein clusters by calpain: A physiological or a pathological role? 116
The calpastatin defect in hypertension is possibly due to a specific degradation by calpain. 116
Interaction between Calpain-1 and HSP90: New Insights into the Regulation of Localization and Activity of the Protease. 116
A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases. 115
Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. 115
Decreased level of calpain inhibitor activity in kidney from Milan hypertensive rats. 114
Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli 114
“In vivo degradation of Nitric-Oxide Synthase isozymes by Calpain is regulated by HSP90” 114
Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate. 113
The calpain-calpastatin system in cystic fibrosis: physiopathological implications 113
Role of calpain in the regulation of CFTR (cystic fibrosis transmembrane conductance regulator) turnover 113
Activation of NADPH oxidase and phosphorylation of membrane proteins in human neutrophils: coordinate inhibition by a surface antigen-directed monoclonal antibody. 112
Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein. 112
Introduction of beta isozyme of protein kinase C accelerates induced differentiation of murine erythroleukemia cells 111
Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic conditions. 111
Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase. 111
Role of calpain-1 in the early phase of experimental ALS 111
Isolation and characterization of calpain activator protein from bovine brain. 109
Fructose 1,6-bisphosphatase: properties of the neutral enzyme and its modification by proteolytic enzymes. 109
Modulation of the intracellular Ca2+-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells 109
Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation 109
“Susceptibility of NOS isoforms to calpain digestion is modulated by the expression levels of HSP90” 108
Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation. 108
Endogenous inhibitors of lysosomal proteinases 108
Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides. Biochem. Biophys. Res. Commun. 193, 941-947 106
Regulation of the Ca2+-dependent neutral proteinases from rabbit liver by an endogenous inhibitor. 106
Differentiation of murine erythroleukemia cells by hexamethylenebisacetamide involves secretion and binding to membranes of a differentiation enhancing factor. 106
Changes in intracellular localization of calpastatin during calpain activation 105
Origin of tryptophan in fructose 1,6-bisphosphatase purified from livers of fed rabbits. 105
Limited proteolysis of liver aldolase and fructose 1,6-bisphosphatase by lysosomal proteinases: effect on complex formation. 105
In vitro correction of erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiency. 105
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. 104
Structural studies on fructose- 1,6-bisphosphatases from rabbit liver, kidney, and muscle. 104
THE CALPAIN-CALPaSTATIN SYSTEM: STRUCTURAL AND FUNCTIONAL PROPERTIES 104
Differentiation of HL60 promyelocytic cells is promoted by a "differentiation enhancing factor" produced by erythroleukemia cells" 103
Evidence for the modification of fructose 1,6-bisphosphatase by two distinct lysosomal proteases. 103
Proteolysis of human reticulocyte membrane proteins: evidence for a physiological role of the acid endopeptidases. 103
Localization of two lysosomal proteinases on the external surface of the lysosomal membrane. 103
Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein 103
Stimulation of erythroleukaemia cell differentiation by extracellular high mobility group-box protein 1 is independent of receptor for advanced glycation end products. 102
Changes in intracellular calpastatin localization are mediated by reversible phosphorylation 102
Selective proinflammatory activation of astrocytes by high mobility group box 1 protein signaling 102
Role of phospholipids in the activation of the Ca2+-dependent neutral proteinase of human erythrocytes. 101
Identification of two calpastatin forms in rat skeletal muscle and their susceptibility to digestion by homologous calpains. 101
Human neuroblastoma cell differentiation requires protein kinase C-θ 100
Binding of monoclonal antibody to cathepsin M located on the external surface of rabbit lysosomes. 100
Purification and properties of rabbit liver cathepsin M and cathepsin B. 100
Decay of proteinase and peptidase activities of human and rabbit erythrocytes during cellular aging. 100
Age-dependent degradation of calpastatin in kidney of hypertensive rats 100
Totale 11.888
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Categoria #
all - tutte 48.707
article - articoli 44.962
book - libri 0
conference - conferenze 3.329
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 416
Totale 97.414
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.749 0 0 0 353 505 553 793 353 474 904 615 199
2020/20211.212 74 117 80 76 78 116 71 115 119 126 115 125
2021/20222.208 48 144 144 247 99 156 173 453 101 232 94 317
2022/20232.216 203 111 17 288 349 449 1 150 416 10 191 31
2023/2024986 54 131 9 102 139 237 33 34 58 18 50 121
2024/2025544 176 246 90 32 0 0 0 0 0 0 0 0
Totale 19.353