TORTOLINA, LORENZO

TORTOLINA, LORENZO  

100007 - Dipartimento di Medicina interna e specialità mediche  

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A multi-scale approach to colorectal cancer: from a biochemical- interaction signaling-network level, to multi-cellular dynamics of malignant transformation. Interplay with mutations and onco-protein inhibitor drugs. 1-gen-2012 Tortolina, Lorenzo; Castagnino, N; De Ambrosi, C; Moran, Eva; Patrone, Franco; Ballestrero, Alberto; Parodi, Silvio
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. 1-gen-2015 Tortolina, Lorenzo; Duffy, Dj; Maffei, Massimo; Castagnino, Nicoletta; Carmody, Am; Kolch, W; Kholodenko, Bn; DE AMBROSI, Cristina; Barla, A; Biganzoli, Em; Nencioni, Alessio; Patrone, Franco; Ballestrero, Alberto; Zoppoli, Gabriele; Verri, Alessandro; Parodi, Silvio
Advances in dynamic modeling of colorectal cancer signalingnetwork regions, a path toward targeted therapies 1-gen-2015 Tortolina, L.; Duffy, D. J.; Maffei, M.; Castagnino, N.; Carmody, A. M.; Kolch, W.; Kholodenko, B. N.; De Ambrosi, C.; Barla, A.; Biganzoli, E. M.; Nencioni, A.; Patrone, F.; Ballestrero, A.; Zoppoli, G.; Verri, A.; Parodi, S.
Computational quantification of global effects induced by mutations and drugs in signaling networks of colorectal cancer cells 1-gen-2021 Sommariva, S.; Caviglia, G.; Ravera, S.; Frassoni, F.; Benvenuto, F.; Tortolina, L.; Castagnino, N.; Parodi, S.; Piana, M.
Dynamic Simulations of Pathway Cross-talks Relevant in Colorectal Cancer: A Quantitative Parameter Sensitivity Analysis 1-gen-2011 DE AMBROSI, Cristina; Barla, Annalisa; Tortolina, Lorenzo; Castagnino, Nicoletta; R., Pesenti; Verri, Alessandro; Ballestrero, Alberto; Patrone, Franco; Parodi, Silvio
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments. Concordance with experimental results. 1-gen-2010 Castagnino, Nicoletta; Tortolina, Lorenzo; Balbi, Alessandro; Pesenti, R; Montagna, R; Ballestrero, Alberto; Soncini, Debora; Moran, E; Nencioni, Alessio; Parodi, Silvio
Dynamic simulations of pathways downstream of TGF-beta , Wnt and EGF-family growth factors, in colorectal cancer, including mutations and treatments with onco-protein inhibitors 1-gen-2012 Tortolina, Lorenzo; Castagnino, Nicoletta; Ambrosi, C. De; Barla, Annalisa; Verri, Alessandro; Zoppoli, G.; Bagnasco, Luca; Piras, Daniela; Patrone, Franco; Ballestrero, Alberto
Dynamic simulations of pathways downstream of TGF-β , Wnt and EGF-family grow- th factors, in colorectal cancer, including mutations and treatments with onco-protein inhibitors 1-gen-2012 Tortolina, Lorenzo; Castagnino, Nicoletta; DE AMBROSI, Cristina; Barla, Annalisa; Verri, Alessandro; Zoppoli, Gabriele; Bagnasco, Luca; D., Piras; Patrone, Franco; Ballestrero, Alberto; Parodi, Silvio
Effects of Parameter Space Exploration within Dynamic Simulations of Pathways Downstream of Erbb-family on Breast Cancer 1-gen-2011 DE AMBROSI, Cristina; Tortolina, Lorenzo; Castagnino, Nicoletta; R., Pesenti; Barla, Annalisa; Verri, Alessandro; Ballestrero, Alberto; Parodi, Silvio
Inhibition of a protein-protein interaction between INI1 and c-Myc by small peptidomimetic molecules inspired by Helix-1 of c-Myc: Identification of a new target of potential antineoplastic interest 1-gen-2007 Bagnasco, Luca; Tortolina, Lorenzo; Biasotti, B.; Castagnino, Nicoletta; Ponassi, Raffaella; Tomati, V.; Nieddu, Erika; Stier, G.; Malacarne, D.; Parodi, Silvio
Parameter Space Exploration within Dynamic Simulations of a Signaling Network Downstream of TGF-beta, WNT and EGF-family growth factors, with reference to colorectal cancer 1-gen-2011 Barla, Annalisa; DE AMBROSI, Cristina; Tortolina, Lorenzo; Castagnino, Nicoletta; Pesenti, R.; Verri, Alessandro; Ballestrero, Alberto; Patrone, F.; Parodi, S.
Parameter Space Exploration within Dynamic Simulations of Signaling Networks 1-gen-2013 C., De Ambrosi; Barla, Annalisa; Tortolina, Lorenzo; Castagnino, Nicoletta; R., Pesenti; Verri, Alessandro; Ballestrero, Alberto; Patrone, Franco; Parodi, Silvio
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial 1-gen-2016 Castagnino, Nicoletta; Maffei, Massimo; Tortolina, Lorenzo; Zoppoli, Gabriele; Piras, Daniela; Nencioni, Alessio; Moran, Eva; Ballestrero, Alberto; Patrone, Franco; Parodi, Silvio
Systems medicine in oncology: Signaling network modeling and new-generation decision-support systems 1-gen-2016 Parodi, Silvio; Riccardi, Giuseppe; Castagnino, Nicoletta; Tortolina, Lorenzo; Maffei, Massimo; Zoppoli, Gabriele; Nencioni, Alessio; Ballestrero, Alberto; Patrone, Franco