FLORIO, TULLIO
 Distribuzione geografica
Continente #
EU - Europa 3.388
Totale 3.388
Nazione #
IT - Italia 3.388
Totale 3.388
Città #
Genova 2.357
Rapallo 655
Genoa 348
Bordighera 28
Totale 3.388
Nome #
Primary Cultures from Human GH-secreting or Clinically Non-functioning Pituitary Adenomas, file e268c4c8-fe1a-a6b7-e053-3a05fe0adea1 226
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion, file e268c4c6-064d-a6b7-e053-3a05fe0adea1 165
Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA, file e268c4c7-3e79-a6b7-e053-3a05fe0adea1 144
Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression, file e268c4c5-ee4b-a6b7-e053-3a05fe0adea1 137
Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects, file e268c4c8-76eb-a6b7-e053-3a05fe0adea1 129
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors, file e268c4cb-1fb3-a6b7-e053-3a05fe0adea1 125
Inhibition of chloride intracellular channel 1 (CLIC1) as biguanide class-effect to impair human glioblastoma stem cell viability, file e268c4c9-2596-a6b7-e053-3a05fe0adea1 124
Ruta graveolens L. induces death of glioblastoma cells and neural progenitors, but not of neurons, via ERK 1/2 and AKT activation, file e268c4c6-7c22-a6b7-e053-3a05fe0adea1 123
Histone Deacetylase Inhibitors Impair Vasculogenic Mimicry from Glioblastoma Cells, file e268c4c9-cbd7-a6b7-e053-3a05fe0adea1 122
Anti-proliferative and anti-secretory effects of everolimus on human pancreatic neuroendocrine tumors primary cultures: is there any benefit from combination with somatostatin analogs?, file e268c4c7-e6de-a6b7-e053-3a05fe0adea1 119
The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells, file e268c4c5-eeb1-a6b7-e053-3a05fe0adea1 118
Calcium binding promotes Prion Protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure, file e268c4c6-0c4b-a6b7-e053-3a05fe0adea1 118
New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells, file e268c4c6-1c8a-a6b7-e053-3a05fe0adea1 111
Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity, file e268c4c9-d3b6-a6b7-e053-3a05fe0adea1 108
Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors, file e268c4c8-0b14-a6b7-e053-3a05fe0adea1 101
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells, file e268c4c7-3b0a-a6b7-e053-3a05fe0adea1 100
A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis, file e268c4c7-b62b-a6b7-e053-3a05fe0adea1 100
The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells, file e268c4c7-91a9-a6b7-e053-3a05fe0adea1 97
Autophagy Activator Drugs: A New Opportunity in Neuroprotection from Misfolded Protein Toxicity, file e268c4c9-fad3-a6b7-e053-3a05fe0adea1 89
Sprouty2 enhances the tumorigenic potential of glioblastoma cells, file e268c4c8-f72a-a6b7-e053-3a05fe0adea1 88
PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs, file e268c4c7-475c-a6b7-e053-3a05fe0adea1 86
Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells, file e268c4cb-eda1-a6b7-e053-3a05fe0adea1 84
Biological and Biochemical Basis of the Differential Efficacy of First and Second Generation Somatostatin Receptor Ligands in Neuroendocrine Neoplasms, file e268c4ca-d085-a6b7-e053-3a05fe0adea1 83
Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells, file e268c4c7-5714-a6b7-e053-3a05fe0adea1 73
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current, file e268c4c6-c279-a6b7-e053-3a05fe0adea1 71
The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells, file e268c4c7-ddfe-a6b7-e053-3a05fe0adea1 69
Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells, file e268c4cb-6507-a6b7-e053-3a05fe0adea1 62
Large expert-curated database for benchmarking document similarity detection in biomedical literature search, file e268c4cc-4e00-a6b7-e053-3a05fe0adea1 52
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives, file e268c4ce-87bd-a6b7-e053-3a05fe0adea1 50
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death, file e268c4c8-572a-a6b7-e053-3a05fe0adea1 40
Compounds and methods for detecting early atherosclerotic lesions in blood vessels, file e268c4cb-1bed-a6b7-e053-3a05fe0adea1 17
Immune Checkpoint Blockade in Lung Carcinoids with Aggressive Behaviour: One More Arrow in Our Quiver?, file e268c4ce-853f-a6b7-e053-3a05fe0adea1 14
Composti e metodi per rilevare lesioni aterosclerotiche precoci in vasi sanguigni, file e268c4cb-4135-a6b7-e053-3a05fe0adea1 12
In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity, file e268c4c9-d3ba-a6b7-e053-3a05fe0adea1 11
Structure and properties of electrochemically synthesized silver nanoparticles in aqueous solution by high-resolution techniques, file e268c4ce-09c4-a6b7-e053-3a05fe0adea1 10
Efficacy of a three drug-based therapy for neuroblastoma in mice, file e268c4cd-dd3c-a6b7-e053-3a05fe0adea1 9
Patient's dermal fibroblasts as disease markers for visceral myopathy, file 13f51b40-46f0-4b98-bdde-57a01cf331da 8
Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors, file e268c4c9-d3c8-a6b7-e053-3a05fe0adea1 7
Proteases Upregulation in Sporadic Alzheimer's Disease Brain, file e268c4c9-d778-a6b7-e053-3a05fe0adea1 7
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors, file e268c4cb-1fb4-a6b7-e053-3a05fe0adea1 7
Emerging multitarget tyrosine kinase inhibitors in the treatment of neuroendocrine neoplasms, file e268c4c9-1160-a6b7-e053-3a05fe0adea1 6
Effects of Prion Protein on Aβ42 and Pyroglutamate-Modified AβpΕ3-42 Oligomerization and Toxicity, file e268c4c9-b9d5-a6b7-e053-3a05fe0adea1 6
A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates, file e268c4c9-c7da-a6b7-e053-3a05fe0adea1 6
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons, file e268c4c9-d59f-a6b7-e053-3a05fe0adea1 6
Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets., file e268c4c9-d774-a6b7-e053-3a05fe0adea1 6
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma, file e268c4c9-d776-a6b7-e053-3a05fe0adea1 6
Two Novel PET Radiopharmaceuticals for Endothelial Vascular Cell Adhesion Molecule-1 (VCAM-1) Targeting, file e268c4cd-a951-a6b7-e053-3a05fe0adea1 6
Commentary: Case Report: Abdominal Lymph Node Metastases of Parathyroid Carcinoma: Diagnostic Workup, Molecular Diagnosis, and Clinical Management, file e268c4cd-c773-a6b7-e053-3a05fe0adea1 6
An overview of long non‐coding (Lnc)rnas in neuroblastoma, file e268c4cd-c828-a6b7-e053-3a05fe0adea1 6
In silico identification and experimental validation of novel anti-Alzheimer's multitargeted ligands from marine source featuring a "2-amino-imidazole plus aromatic group" scaffold, file e268c4c9-d3be-a6b7-e053-3a05fe0adea1 5
Novel celecoxib analogues inhibit glial production of prostaglandinE2, nitric oxide, and oxygen radicals reverting the neuroinflammatoryresponses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide, file e268c4c9-d5a2-a6b7-e053-3a05fe0adea1 5
Drug-repositioning opportunities for cancer therapy: Novel molecular targets for known compounds, file e268c4c9-d770-a6b7-e053-3a05fe0adea1 5
Molecular pharmacology of malignant pleural mesothelioma: Challenges and perspectives from preclinical and clinical studies, file e268c4c9-d772-a6b7-e053-3a05fe0adea1 5
Canine osteosarcoma cell lines contain stem-like cancer cells: Biological and pharmacological characterization, file e268c4c9-fcdf-a6b7-e053-3a05fe0adea1 5
Development and validation of a GC-MS method for determination of metformin in normal brain and in glioblastoma tissues, file 69a3d5e9-2837-4372-9465-d6a9319685d7 4
Biomimetic vesicles for glioblastoma treatment, file 962fac15-1e9a-4dff-8c52-a02828c25197 4
OXIDATIVE STRESS IN CANCER STEM-LIKE CELLS: BIOLOGY AND MODULATION STRATEGIES, file e268c4c7-0e60-a6b7-e053-3a05fe0adea1 4
Mutual influence of ROS, pH and CLIC1 membrane protein in the regulation of G1/S phase progression in human glioblastoma stem cells, file e268c4c9-d3b8-a6b7-e053-3a05fe0adea1 4
A liposomal formulation for inflammation targeting, file e268c4cb-5f21-a6b7-e053-3a05fe0adea1 4
Cross talk between mesenchymal and glioblastoma stem cells: Communication beyond controversies, file e268c4cc-a873-a6b7-e053-3a05fe0adea1 4
MCM2 and Carbonic Anhydrase 9 Are Novel Potential Targets for Neuroblastoma Pharmacological Treatment, file e268c4cc-f0a6-a6b7-e053-3a05fe0adea1 4
Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research, file e268c4cd-71e2-a6b7-e053-3a05fe0adea1 4
Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment, file 1bd89405-ac27-4c72-b331-86c4f0869e09 3
FGFR4 polymorphism as molecular determinant of the efficacy of mTOR inhibitors in GH-secreting pituitary adenomas, file e268c4c7-570f-a6b7-e053-3a05fe0adea1 3
Down-regulation of 21A Alu RNA as a tool to boost proliferation maintaining the tissue regeneration potential of progenitor cells, file e268c4c7-5ebc-a6b7-e053-3a05fe0adea1 3
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells, file e268c4c9-b3b5-a6b7-e053-3a05fe0adea1 3
Subventricular zone microenvironment protects glioblastoma cells from radiotherapy cytotoxicity: Role of the chemokine CXCL12, file e268c4c9-b3b7-a6b7-e053-3a05fe0adea1 3
Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer, file e268c4c9-d3c3-a6b7-e053-3a05fe0adea1 3
Does pasireotide directly modulate skeletal muscle metabolism?, file e268c4c9-d595-a6b7-e053-3a05fe0adea1 3
Drug design strategies focusing on the CXCR4/CXCR7/CXCL12 pathway in leukemia and lymphoma, file e268c4ca-0e16-a6b7-e053-3a05fe0adea1 3
Radiofarmaci per la diagnosi precoce delle lesioni aterosclerotiche, file e268c4cb-5f1b-a6b7-e053-3a05fe0adea1 3
Development of gel formulations for localized release of metformin, file e268c4cb-68dd-a6b7-e053-3a05fe0adea1 3
Octreotide and pasireotide combination treatment in somatotroph tumor cells: Predominant role of sst2 in mediating ligand effects, file e268c4cd-ac32-a6b7-e053-3a05fe0adea1 3
N6-isopentenyladenosine hinders the vasculogenic mimicry in human glioblastoma cells through Src-120 catenin pathway modulation and RhoA activity inhibition, file e268c4ce-1e6b-a6b7-e053-3a05fe0adea1 3
Development of Biotinylated Liposomes Encapsulating Metformin for Therapeutic Targeting of Inflammation-Based Diseases, file 7feffea1-8ce9-4fd8-9ac6-75604a9655c5 2
CXCR4 and SDF1 expression in human meningiomas: a proliferative role in tumor meningothelial cells in vitro, file e268c4c5-eefd-a6b7-e053-3a05fe0adea1 2
An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells., file e268c4c5-f4ec-a6b7-e053-3a05fe0adea1 2
Celecoxib, a COX-2 inhibitor, blocks microglial activation induced by a neurotoxic conformer of hPrP90-231, file e268c4c6-2de3-a6b7-e053-3a05fe0adea1 2
Composti e metodi per rilevare lesioni aterosclerotiche precoci in vasi sanguigni, file e268c4cc-1922-a6b7-e053-3a05fe0adea1 2
Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas, file e268c4cc-baf7-a6b7-e053-3a05fe0adea1 2
Immunotherapy of Neuroendocrine Neoplasms: Any Role for the Chimeric Antigen Receptor T Cells?, file 3f979797-3904-42fc-96b4-4a8b835224f8 1
Editorial: "Small molecules targeting transmembrane receptors and ion channels in drug discovery", file 47a4239e-46a2-4e66-9539-34119139409c 1
Cellular Mechanosensitivity: Validation of an Adaptable 3D-Printed Device for Microindentation, file deac2e07-4bd4-4853-8b2d-756b3beebda1 1
Differential efficacy of SSTR1, 2 and 5 agonists in the inhibition of C6 glioma growth in nude mice, file e268c4c5-eeaf-a6b7-e053-3a05fe0adea1 1
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction, file e268c4c6-0eb5-a6b7-e053-3a05fe0adea1 1
Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA, file e268c4c6-1ad9-a6b7-e053-3a05fe0adea1 1
Amyloid precursor protein and Presenilin 1 interaction studied by FRET in human H4 cells., file e268c4c8-b52e-a6b7-e053-3a05fe0adea1 1
ACTIVATION OF AUTOPHAGY PATHWAY AS NEUROPROTECTIVE MECHANISM AGAINST AMYLOIDOGENIC PRION PEPTIDE, file e268c4c9-667b-a6b7-e053-3a05fe0adea1 1
Injectable formulations for local administration of metformin hydrochloride, file e268c4cb-0220-a6b7-e053-3a05fe0adea1 1
Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization, file e268c4cc-d96d-a6b7-e053-3a05fe0adea1 1
Co-Administration of Fendiline Hydrochloride Enhances Chemotherapeutic Efficacy of Cisplatin in Neuroblastoma Treatment, file e268c4cc-dcbd-a6b7-e053-3a05fe0adea1 1
Extracellular Vesicles Loaded miRNAs as Potential Modulators Shared Between Glioblastoma, and Parkinson’s and Alzheimer’s Diseases, file e268c4cd-21da-a6b7-e053-3a05fe0adea1 1
Bioinspired nanoparticles for glioblastoma treatment, file e60c8a68-11f0-43bc-885e-cc81826d1948 1
Totale 3.388
Categoria #
all - tutte 8.142
article - articoli 8.087
book - libri 0
conference - conferenze 26
curatela - curatele 0
other - altro 0
patent - brevetti 29
selected - selezionate 0
volume - volumi 0
Totale 16.284


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019158 0 0 0 0 0 0 0 0 0 0 8 150
2019/2020778 7 5 20 34 68 87 99 96 126 101 90 45
2020/2021691 49 63 45 49 74 53 30 56 36 106 69 61
2021/2022735 67 20 53 35 68 27 27 39 52 42 240 65
2022/2023723 17 28 191 95 48 179 36 41 8 27 44 9
2023/2024279 11 11 41 5 28 24 70 36 14 28 11 0
Totale 3.388