adenine is a machine learning framework designed for biological data exploration and visualization. Its goal is to help bioinformaticians achieving a first and quick overview of the main structures underlying their data. This software tool encompasses state-of-the-art techniques for missing values imputing, data preprocessing, dimensionality reduction and clustering. adenine has a scalable architecture which seamlessly work on single workstations as well as on high-performance computing facilities. adenine is capable of generating publication-ready plots along with quantitative descriptions of the results. In this paper we provide an example of exploratory analysis on a publicly available gene expression data set of colorectal cancer samples. The software and its documentation are available at https://github.com/slipguru/adenine under FreeBSD license.
Adenine: A HPC-oriented tool for biological data exploration
Fiorini, Samuele;Tomasi, Federico;Squillario, Margherita;Barla, Annalisa
2019
Abstract
adenine is a machine learning framework designed for biological data exploration and visualization. Its goal is to help bioinformaticians achieving a first and quick overview of the main structures underlying their data. This software tool encompasses state-of-the-art techniques for missing values imputing, data preprocessing, dimensionality reduction and clustering. adenine has a scalable architecture which seamlessly work on single workstations as well as on high-performance computing facilities. adenine is capable of generating publication-ready plots along with quantitative descriptions of the results. In this paper we provide an example of exploratory analysis on a publicly available gene expression data set of colorectal cancer samples. The software and its documentation are available at https://github.com/slipguru/adenine under FreeBSD license.
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