Copolymers containing aldehydic, 4-aminobutyl and 6-aminohexyl residues were prepared by radical copolymerization of N,N-dimethylacrylamide (DMAA) with methacrolein and hydrochlorides of 4-(4-aminobutyl)styrene and N-acryloyl-1,6-diaminohexane. Copolymers containing L-lysine, 2-aminoethyl and 4-aminobutyl residues were prepared by copolymerization of the methacryloxyethyl ester of L-Nα,Nε-diBoc lysine, N-acryloyl-N’-Boc-1,2-diaminoethane and N-acryloyl-N’-Boc-1,4-diaminobutane with DMAA followed by deprotection. Some of the prepared copolymers were employed in experiments of gelatin crosslinking also in the presence of copper amine oxidase enzymes.
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Titolo: | Synthesis of functionalized vinyl copolymers to use as polymeric crosslinkers in the preparation of gelatin-based scaffolds |
Autori: | |
Data di pubblicazione: | 2011 |
Abstract: | Copolymers containing aldehydic, 4-aminobutyl and 6-aminohexyl residues were prepared by radical copolymerization of N,N-dimethylacrylamide (DMAA) with methacrolein and hydrochlorides of 4-(4-aminobutyl)styrene and N-acryloyl-1,6-diaminohexane. Copolymers containing L-lysine, 2-aminoethyl and 4-aminobutyl residues were prepared by copolymerization of the methacryloxyethyl ester of L-Nα,Nε-diBoc lysine, N-acryloyl-N’-Boc-1,2-diaminoethane and N-acryloyl-N’-Boc-1,4-diaminobutane with DMAA followed by deprotection. Some of the prepared copolymers were employed in experiments of gelatin crosslinking also in the presence of copper amine oxidase enzymes. |
Handle: | http://hdl.handle.net/11567/276923 |
ISBN: | 9788895028835 |
Appare nelle tipologie: | 04.01 - Contributo in atti di convegno |